C07C61/04

INCENSE ODORANT
20240199524 · 2024-06-20 ·

The present invention relates to the field of perfumery. More particularly, it concerns a composition of matter comprising a compound of formula (I) as defined below wherein the weight ratio of the cis-diastereoisomers to the trans-diastereoisomers is comprised in the range between 90:10 and 99.5:0.5 and comprising at least 10% w/w of cis-(1S,2R) diastereoisomer. Said composition of matter is a useful perfumery ingredient, and therefore the present invention comprises the invention composition of matter as part of a perfuming composition or of a perfuming consumer product.

INCENSE ODORANT
20240199524 · 2024-06-20 ·

The present invention relates to the field of perfumery. More particularly, it concerns a composition of matter comprising a compound of formula (I) as defined below wherein the weight ratio of the cis-diastereoisomers to the trans-diastereoisomers is comprised in the range between 90:10 and 99.5:0.5 and comprising at least 10% w/w of cis-(1S,2R) diastereoisomer. Said composition of matter is a useful perfumery ingredient, and therefore the present invention comprises the invention composition of matter as part of a perfuming composition or of a perfuming consumer product.

ALPHA-TRUXILLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS THEREOF

The present invention provides a compound, and method of inhibiting the activity of a Fatty Acid Binding Protein (FABP) comprising contacting the FABP with a compound, said compound having the structure: Formula (I)

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RADIATION-SENSITIVE RESIN COMPOSITION, PATTERN FORMATION METHOD, METHOD FOR MANUFACTURING SUBSTRATE, AND COMPOUND
20240319597 · 2024-09-26 · ·

A radiation-sensitive resin composition includes: a compound A represented by formula (I); a resin B including a structural unit having an acid-dissociable group; a radiation-sensitive acid generator other than the compound A; and a solvent. R.sup.1 is an (m+m)-valent organic group and comprises a cyclopropane ring skeleton, a cyclobutane ring skeleton, or both; X.sup.1 is a group represented by formula (1-1) or a group represented by formula (1-2); X.sup.2 is a group represented by formula (2-1) or a group represented by formula (2-2); Y.sup.+ is a monovalent onium cation; m is an integer of 1 to 2, and m is an integer of 0 to 1. * represents a bond to another group.

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PHARMACEUTICAL CO-CRYSTAL COMPOSITION AND USE THEREOF
20180186822 · 2018-07-05 ·

The current invention relates to series of co-crystals of platinum analogues and their pharmaceutical use. The co-crystals of the subject invention may be used in the treatment or prevention of cancers and virus infections.

PHARMACEUTICAL CO-CRYSTAL COMPOSITION AND USE THEREOF
20180186822 · 2018-07-05 ·

The current invention relates to series of co-crystals of platinum analogues and their pharmaceutical use. The co-crystals of the subject invention may be used in the treatment or prevention of cancers and virus infections.

2-OCTYLCYCLOPROPYL-1-CARBOXYLIC ACID AND THE ISOMERS THEREOF, AND USES OF SAME
20180163157 · 2018-06-14 ·

The invention relates to 2-octylcyclopropyl-1-carboxylic acid, in particular in the form of one of the isomers thereof in isolated form or in the form of a mixture of at least two of said isomers. The invention further relates to a method for synthesizing 2-octylcyclopropyl-1-carboxylic acid or at least one of the isomers thereof. Finally, the invention relates to the use of 2-octylcyclopropyl-1-carboxylic acid or of one of said isomers in isolated form or of one of the mixtures of at least two of the isomers thereof, as a perfuming agent. The invention further relates to the compositions including 2-octylcyclopropyl-1-carboxylic acid or one of said isomers in isolated form or one of the mixtures of at least two of the isomers thereof, as a perfuming agent.

2-OCTYLCYCLOPROPYL-1-CARBOXYLIC ACID AND THE ISOMERS THEREOF, AND USES OF SAME
20180163157 · 2018-06-14 ·

The invention relates to 2-octylcyclopropyl-1-carboxylic acid, in particular in the form of one of the isomers thereof in isolated form or in the form of a mixture of at least two of said isomers. The invention further relates to a method for synthesizing 2-octylcyclopropyl-1-carboxylic acid or at least one of the isomers thereof. Finally, the invention relates to the use of 2-octylcyclopropyl-1-carboxylic acid or of one of said isomers in isolated form or of one of the mixtures of at least two of the isomers thereof, as a perfuming agent. The invention further relates to the compositions including 2-octylcyclopropyl-1-carboxylic acid or one of said isomers in isolated form or one of the mixtures of at least two of the isomers thereof, as a perfuming agent.

Elastin synthesis/regeneration promoting agent

8-[2-(2-Pentyl-cyclopropylmethyl)-cyclopropyl]-octanoic acid (DCP-LA) has an action to promote synthesis and regeneration of elastin, and is useful as an agent for the prophylaxis or improvement of wrinkles, and an anti-aging drug.

SYNTHESIS OF RAS INHIBITORS

The present invention relates to Ras inhibitors and to methods for preparing Ras inhibitors.