A shock-absorbing, waterproof, and breathable shoe sole is provided, including a midsole. The top of the midsole is provided with a concavity, and the bottom of the concavity is provided with multiple breathable grooves. The left and right side walls of the breathable grooves are provided with through holes connected to the outside. A gasket is adapted to be placed in the concavity, and the gasket is integrally formed from a support plate and a breathable waterproof cloth. The support plate is provided with multiple breathable holes aligned with the breathable grooves. The shoe sole of this application is provided with multiple breathable grooves, and the inner wall of the breathable grooves is provided with through holes that connect to the outside.