The present disclosure relates to a method and a system for manufacturing an ester-based composition which are characterized in sequentially operating a plurality of batch reactors, and since an ester-based composition is semi-continuously manufactured, the productivity is high and the stability of a batch reactor is secured.

The present disclosure relates to a system and a method for continuously purifying a reaction product of esterification, where the system includes a neutralizer, a distiller, and a product purifier. Through the present system and the method, it is possible to perform a continuous purification process efficiently, and to reduce lower alcohol wastewater generated during purification.

The present disclosure relates to a system and a method for continuously purifying a reaction product of esterification, where the system includes a neutralizer, a distiller, and a product purifier. Through the present system and the method, it is possible to perform a continuous purification process efficiently, and to reduce lower alcohol wastewater generated during purification.

The present disclosure provides methods for conducting chemical reactions and for conducting a multi-step chemical reactions using swellable organically modified silica (SOMS) as nanoreactors.

The present disclosure provides methods for conducting chemical reactions and for conducting a multi-step chemical reactions using swellable organically modified silica (SOMS) as nanoreactors.

The present invention relates to hyperpolarized [3-.sup.13C]acetoacetate. Provided are [3-.sup.13C]acetoacetate and compositions comprising said [3-.sup.13C]acetoacetate. Further provided are methods of preparing and using hyperpolarized [3-.sup.13C]acetoacetate in the determination of the spatial and temporal distribution and metabolism of [3-.sup.13C]acetoacetate and/or its metabolites in a cell or subject, preferably by magnetic resonance imaging (MRI), magnetic resonance spectroscopy (MRS), and/or magnetic resonance spectroscopic imaging (MRSI), whereby conditions, diseases, or disorders associated with the metabolism of acetoacetate and/or other ketone bodies can be diagnosed. The conditions, diseases, or disorders to be diagnosed preferably are cancer, diabetes, cardiovascular diseases, or neurodegenerative diseases.

The present invention relates to hyperpolarized [3-.sup.13C]acetoacetate. Provided are [3-.sup.13C]acetoacetate and compositions comprising said [3-.sup.13C]acetoacetate. Further provided are methods of preparing and using hyperpolarized [3-.sup.13C]acetoacetate in the determination of the spatial and temporal distribution and metabolism of [3-.sup.13C]acetoacetate and/or its metabolites in a cell or subject, preferably by magnetic resonance imaging (MRI), magnetic resonance spectroscopy (MRS), and/or magnetic resonance spectroscopic imaging (MRSI), whereby conditions, diseases, or disorders associated with the metabolism of acetoacetate and/or other ketone bodies can be diagnosed. The conditions, diseases, or disorders to be diagnosed preferably are cancer, diabetes, cardiovascular diseases, or neurodegenerative diseases.

A process for chemically recycling polyethylene terephthalate (PET) which utilizes a microwave absorber to optimize glycolytic depolymerization of PET via microwave irradiation. The method of chemically degrading PET to its reactive intermediate, bis(2-hydroxyethyl) terephthalate (BHET), is carried out by: (a) combining PET with ethylene glycol and a catalytic system comprising a catalyst and a microwave absorber to produce a heterogeneous reaction mixture; and then (b) heating by microwave irradiating the reaction mixture to a temperature sufficient to produce a reaction product comprising BHET. The BHET monomer then can be purified and re-polymerized to form new, virgin PET.

A process for chemically recycling polyethylene terephthalate (PET) which utilizes a microwave absorber to optimize glycolytic depolymerization of PET via microwave irradiation. The method of chemically degrading PET to its reactive intermediate, bis(2-hydroxyethyl) terephthalate (BHET), is carried out by: (a) combining PET with ethylene glycol and a catalytic system comprising a catalyst and a microwave absorber to produce a heterogeneous reaction mixture; and then (b) heating by microwave irradiating the reaction mixture to a temperature sufficient to produce a reaction product comprising BHET. The BHET monomer then can be purified and re-polymerized to form new, virgin PET.

The invention relates to a process for the chromatographic purification of a starting stream containing ammonium sulfate and 2-hydroxy-2-methylpropionic acid, comprising: passage of the starting stream through a bed of stationary phase; elution of a raffinate enriched in ammonium sulfate and depleted in 2-hydroxy-2-methylpropionic acid; and elution of an extract enriched in 2-hydroxy-2-methylpropionic acid and depleted in ammonium sulfate.