C07C215/46

(HETERO)ARYL CYCLOPROPYLAMINE COMPOUNDS AS LSD1 INHIBITORS

The invention relates to (hetero)aryl cyclopropylamine compounds, including particularly the compounds of formula (I) as described and defined herein, and their use in therapy, including, e.g., in the treatment or prevention of cancer, a neurological disease or condition, or a viral infection.

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(HETERO)ARYL CYCLOPROPYLAMINE COMPOUNDS AS LSD1 INHIBITORS

The invention relates to (hetero)aryl cyclopropylamine compounds, including particularly the compounds of formula (I) as described and defined herein, and their use in therapy, including, e.g., in the treatment or prevention of cancer, a neurological disease or condition, or a viral infection.

##STR00001##

(Hetero)aryl cyclopropylamine compounds as LSD1 inhibitors

The invention relates to (hetero)aryl cyclopropylamine compounds, including particularly the compounds of formula (I) as described and defined herein, and their use in therapy, including, e.g., in the treatment or prevention of cancer, a neurological disease or condition, or a viral infection. ##STR00001##

(Hetero)aryl cyclopropylamine compounds as LSD1 inhibitors

The invention relates to (hetero)aryl cyclopropylamine compounds, including particularly the compounds of formula (I) as described and defined herein, and their use in therapy, including, e.g., in the treatment or prevention of cancer, a neurological disease or condition, or a viral infection. ##STR00001##

2,5,6-TRICHLORODOPAMINE: SYNTHESIS AND APPLICATIONS

A compound having formula 1 or a salt thereof:

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A method for making the compound having formula 1 includes a step of reacting dopamine.Math.HCL with hypochlorous acid in a reaction solvent to form the compound having formula 1 or a salt thereof. The reaction can take place in a polar or nonpolar solvent.

2,5,6-TRICHLORODOPAMINE: SYNTHESIS AND APPLICATIONS

A compound having formula 1 or a salt thereof:

##STR00001##

A method for making the compound having formula 1 includes a step of reacting dopamine.Math.HCL with hypochlorous acid in a reaction solvent to form the compound having formula 1 or a salt thereof. The reaction can take place in a polar or nonpolar solvent.