C07C217/54

TREATMENT AND DIAGNOSIS OF MELANOMA
20210220306 · 2021-07-22 ·

The present invention discloses novel agents and methods for diagnosis and treatment of melanoma. Also disclosed are related arrays, kits, and screening methods.

Zuclomiphene Salts and Crystalline Forms Thereof

The present invention provides zuclomiphene salts, zuclomiphene binaphthyl hydrogen phosphate salt (1-A)⋅(BPA) and zuclomiphene oxalate salt (1-A)⋅(OXL), crystalline forms thereof and processes for the preparation thereof.

Treatment and diagnosis of melanoma

The present invention discloses novel agents and methods for diagnosis and treatment of melanoma. Also disclosed are related arrays, kits, and screening methods.

Treatment and diagnosis of melanoma

The present invention discloses novel agents and methods for diagnosis and treatment of melanoma. Also disclosed are related arrays, kits, and screening methods.

Substituted phenethylamine derivatives

Embodiments of the present disclosure describe substituted phenethylamine derivatives, compositions comprising the substituted phenethylamine derivatives, methods of making the substituted phenethylamine derivatives, and methods of using the phenethylamine derivatives, and the like. Exemplary compounds of the present disclosure include compounds of the formula (I) and (II): ##STR00001##
wherein X, R.sup.a, R.sup.b, R.sup.c, R.sup.1, R.sup.2, R.sup.3, and R.sup.4 are defined elsewhere.

Substituted phenethylamine derivatives

Embodiments of the present disclosure describe substituted phenethylamine derivatives, compositions comprising the substituted phenethylamine derivatives, methods of making the substituted phenethylamine derivatives, and methods of using the phenethylamine derivatives, and the like. Exemplary compounds of the present disclosure include compounds of the formula (I) and (II): ##STR00001##
wherein X, R.sup.a, R.sup.b, R.sup.c, R.sup.1, R.sup.2, R.sup.3, and R.sup.4 are defined elsewhere.

Carbon dioxide as a directing group for C—H functionalization reactions involving Lewis basic amines, alcohols, thiols, and phosphines for the synthesis of compounds

Methods of synthesizing compounds using CO.sub.2 as a directing group for CH functionalization, and compounds made thereby, are described.

Carbon dioxide as a directing group for C—H functionalization reactions involving Lewis basic amines, alcohols, thiols, and phosphines for the synthesis of compounds

Methods of synthesizing compounds using CO.sub.2 as a directing group for CH functionalization, and compounds made thereby, are described.

Treatment and diagnosis of melanoma

The present invention discloses novel agents and methods for diagnosis and treatment of melanoma. Also disclosed are related arrays, kits, and screening methods.

Treatment and diagnosis of melanoma

The present invention discloses novel agents and methods for diagnosis and treatment of melanoma. Also disclosed are related arrays, kits, and screening methods.