Compositions and methods are provided for reducing, inhibiting, or preventing corrosion of a surface, the method comprising contacting an anticorrosion compound of Formula 1 with the surface, the anticorrosion compound of Formula 1 having a structure corresponding to:

##STR00001##

wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, and R.sup.5 are independently selected from hydrogen, hydroxyl, alkyl, alkoxyl, aryl, alkaryl, aralkyl, and NR.sup.8R.sup.9; R.sup.6 and R.sup.7 are independently hydrogen, a substituted alkyl, substituted alkenyl, substituted aryl, substituted alkaryl, or substituted aralkyl, wherein at least one substituent is a hydroxyl or an ether; provided that at least one of R.sup.6 and R.sup.7 is other than hydrogen; R.sup.8 and R.sup.9 are independently hydrogen, unsubstituted alkyl, unsubstituted alkenyl, unsubstituted aryl, unsubstituted alkaryl, unsubstituted aralkyl, substituted alkyl, substituted alkenyl, or substituted alkaryl, wherein at least one substituent is a hydroxyl or an ether; or any two adjacent groups of R.sup.1, R.sup.2, R.sup.3, R.sup.4, and R.sup.5 form one or more ring structures.

Compositions and methods are provided for reducing, inhibiting, or preventing corrosion of a surface, the method comprising contacting an anticorrosion compound of Formula 1 with the surface, the anticorrosion compound of Formula 1 having a structure corresponding to:

##STR00001##

wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, and R.sup.5 are independently selected from hydrogen, hydroxyl, alkyl, alkoxyl, aryl, alkaryl, aralkyl, and NR.sup.8R.sup.9; R.sup.6 and R.sup.7 are independently hydrogen, a substituted alkyl, substituted alkenyl, substituted aryl, substituted alkaryl, or substituted aralkyl, wherein at least one substituent is a hydroxyl or an ether; provided that at least one of R.sup.6 and R.sup.7 is other than hydrogen; R.sup.8 and R.sup.9 are independently hydrogen, unsubstituted alkyl, unsubstituted alkenyl, unsubstituted aryl, unsubstituted alkaryl, unsubstituted aralkyl, substituted alkyl, substituted alkenyl, or substituted alkaryl, wherein at least one substituent is a hydroxyl or an ether; or any two adjacent groups of R.sup.1, R.sup.2, R.sup.3, R.sup.4, and R.sup.5 form one or more ring structures.

Disclosed herein are addition-polymerizable monomer composition including an amine-derivatized alpha-methyl styrene (ADAMS) monomer according to structure (I) and/or an aminated conjugated aliphatic methylated polyene (ACAMP) monomer according to structure (II):

##STR00001##

with k, R.sub.1, R.sub.2, R.sub.3, and R.sub.4 defined herein. Difunctional monomers of these types with two polymerizable loci and/or two amine loci are also disclosed herein. Further disclosed herein are methods for making such compositions.

Disclosed herein are addition-polymerizable monomer composition including an amine-derivatized alpha-methyl styrene (ADAMS) monomer according to structure (I) and/or an aminated conjugated aliphatic methylated polyene (ACAMP) monomer according to structure (II):

##STR00001##

with k, R.sub.1, R.sub.2, R.sub.3, and R.sub.4 defined herein. Difunctional monomers of these types with two polymerizable loci and/or two amine loci are also disclosed herein. Further disclosed herein are methods for making such compositions.

The present invention relates to a process for the preparation of 4-aminobenzoamidine (4-AMBA) salts of general formula (I)

##STR00001##

preferably the salts thereof with hydrochloric or hydrobromic acid, particularly preferred the dichloride salt.

The present invention relates to a process for the preparation of 4-aminobenzoamidine (4-AMBA) salts of general formula (I)

##STR00001##

preferably the salts thereof with hydrochloric or hydrobromic acid, particularly preferred the dichloride salt.

Methods are provided for modulating MRGPR X4 generally, or for treating a MRGPR X4 dependent condition more specifically, by contacting the MRGPR X4 or administering to a subject in need thereof, respectively, an effective amount of a compound having the structure of Formula (I):

##STR00001##

or a pharmaceutically acceptable isomer, racemate, hydrate, solvate, isotope, or salt thereof, wherein n, x, A, Q.sub.1, Q.sub.2, Z, R, R.sup.1, R.sup.2, R.sup.3, R.sup.4 and R.sup.5 are as defined herein. Pharmaceutical compositions containing such compounds, as well as to compounds themselves, are also provided.

The present invention relates to a process for the preparation of 4-aminobenzoamidine (4-AMBA) salts of general formula (I) ##STR00001##
preferably the salts thereof with hydrochloric or hydrobromic acid, particularly preferred the dichloride salt.

The present invention relates to a process for the preparation of 4-aminobenzoamidine (4-AMBA) salts of general formula (I) ##STR00001##
preferably the salts thereof with hydrochloric or hydrobromic acid, particularly preferred the dichloride salt.

The present invention relates to a compound of formula I, or an isotopic form, stereoisomer, a tautomer, a pharmaceutically acceptable salt, a solvate, a polymorph, a prodrug, N-oxide or S-oxide thereof; and processes for their preparation. The invention further relates to pharmaceutical compositions containing the compounds and their use in the treatment of diseases or disorders mediated by ROR.