Patent classifications
C07C227/02
PROCESS FOR MANUFACTURING CARBOXYLIC ACIDS
The present invention is directed towards a process for the synthesis of compounds with the general formula (II) or their respective alkali metal salts by oxidation of compounds of general formula (I) with oxygen
##STR00001## in the presence of a heterogeneous catalyst containing a metal of group 10 of the periodic table of the elements, wherein R.sup.1 and R.sup.2 and R.sup.3 are same or different and selected from H and C.sub.1-C.sub.6-alkyl, non-substituted or substituted with one or more moieties selected from COOH and O-R.sup.4 with R.sup.4 being selected from H and C.sub.1-C.sub.4-alkyl.
Synthesis of an antiviral compound
- Amy Cagulada ,
- Johann Chan ,
- Lina Chan ,
- Denise A. Colby ,
- Kapil Kumar Karki ,
- Darryl Kato ,
- Katie Ann Keaton ,
- Sudha Kondappally ,
- Chris Levins ,
- Adam Littke ,
- Ruben Martinez ,
- Dominika Pcion ,
- Troy Reynolds ,
- Bruce Ross ,
- Michael Sangi ,
- Adam J. Schrier ,
- Pamela Seng ,
- Dustin Siegel ,
- Nathan Shapiro ,
- Donald Tang ,
- James G. Taylor ,
- Jonathan Tripp ,
- Andrew W. Waltman ,
- Lawrence Yu
The present disclosure provides processes for the preparation of a compound of formula I: ##STR00001##
which is useful as an antiviral agent. The disclosure also provides compounds and processes for the preparation of the compounds that are synthetic intermediates to the compound of formula I.
PROCESS FOR THE PREPARATION OF A SULFUR-AMINE
The present invention relates to a process for the synthesis of cysteamine or a salt thereof.
PROCESS FOR THE PREPARATION OF A SULFUR-AMINE
The present invention relates to a process for the synthesis of cysteamine or a salt thereof.
SYNTHESIS OF RAS INHIBITORS
The present invention relates to Ras inhibitors and to methods for preparing Ras inhibitors.
SYNTHESIS OF RAS INHIBITORS
The present invention relates to Ras inhibitors and to methods for preparing Ras inhibitors.
Methods of producing cancer targeting compounds
Provided herein are methods of making the compound of Formula I: ##STR00001##
and certain intermediates involved in such process.
Methods of producing cancer targeting compounds
Provided herein are methods of making the compound of Formula I: ##STR00001##
and certain intermediates involved in such process.
Process for the preparation of 4-dimethylaminocrotonic acid
The present invention provides a process for the preparation of 4-dimethylaminocrotonic acid of Formula (II) or its salts, which is used as an intermediate for the preparation of afatinib or its salts. ##STR00001##
Process for the preparation of 4-dimethylaminocrotonic acid
The present invention provides a process for the preparation of 4-dimethylaminocrotonic acid of Formula (II) or its salts, which is used as an intermediate for the preparation of afatinib or its salts. ##STR00001##