C07C227/12

POSITRON IMAGING TOMOGRAPHY IMAGING AGENT COMPOSITION AND METHOD FOR BACTERIAL INFECTION

The present invention provides a composition comprising the compound having the structure:

##STR00001##

or a salt of the compound; 4-amino-2-[.sup.19F]-fluorobenzoic acid or a salt of 4-amino-2-[.sup.19F]-fluorobenzoic acid; and at least one acceptable carrier.

POSITRON IMAGING TOMOGRAPHY IMAGING AGENT COMPOSITION AND METHOD FOR BACTERIAL INFECTION

The present invention provides a composition comprising the compound having the structure:

##STR00001##

or a salt of the compound; 4-amino-2-[.sup.19F]-fluorobenzoic acid or a salt of 4-amino-2-[.sup.19F]-fluorobenzoic acid; and at least one acceptable carrier.

Pharmaceutically active compounds

The invention is directed to compounds of general formula (I), and pharmaceutical compositions containing such compounds. The compounds and compositions have valuable pharmaceutical properties. In particular, they may be used for the treatment of cancer. Novel intermediates and novel methods of preparation are also disclosed. ##STR00001##

Pharmaceutically active compounds

The invention is directed to compounds of general formula (I), and pharmaceutical compositions containing such compounds. The compounds and compositions have valuable pharmaceutical properties. In particular, they may be used for the treatment of cancer. Novel intermediates and novel methods of preparation are also disclosed. ##STR00001##

Pharmaceutically active compounds

The invention is directed to compounds of general formula (I), and pharmaceutical compositions containing such compounds. The compounds and compositions have valuable pharmaceutical properties. In particular, they may be used for the treatment of cancer. Novel intermediates and novel methods of preparation are also disclosed. ##STR00001##

CATALYST FOR PIR/PUR FOAM PRODUCTION

The present disclosure is related to a catalyst for PIR/PUR foam production comprising a compound having the general formula (I) wherein R.sub.1 and R.sub.2 are independently selected from a C.sub.1-C.sub.18 straight-chain or branched alkyl group, unsubstituted or substituted with one or more hydroxyl, amino or aminoalkyl groups, or R.sub.1 and R.sub.2, taken together, form a 5- or 6-membered ring or 7-membered bicyclic structure, one of the members of the ring or bicyclic structure being X, wherein X is selected from CH.sub.2, O, S, NCH.sub.3 or NCH.sub.2COOM, wherein R.sub.3 and R.sub.4 are independently selected from hydrogen or a C.sub.1-C.sub.4 straight-chain or branched alkyl group and wherein M is an alkali metal ion or a quaternary ammonium ion, as well as to a process for production of said compound and uses thereof and to a process for the production of PIR/PUR foam or flexible foam in the presence of the catalyst of the present disclosure.

##STR00001##

CATALYST FOR PIR/PUR FOAM PRODUCTION

The present disclosure is related to a catalyst for PIR/PUR foam production comprising a compound having the general formula (I) wherein R.sub.1 and R.sub.2 are independently selected from a C.sub.1-C.sub.18 straight-chain or branched alkyl group, unsubstituted or substituted with one or more hydroxyl, amino or aminoalkyl groups, or R.sub.1 and R.sub.2, taken together, form a 5- or 6-membered ring or 7-membered bicyclic structure, one of the members of the ring or bicyclic structure being X, wherein X is selected from CH.sub.2, O, S, NCH.sub.3 or NCH.sub.2COOM, wherein R.sub.3 and R.sub.4 are independently selected from hydrogen or a C.sub.1-C.sub.4 straight-chain or branched alkyl group and wherein M is an alkali metal ion or a quaternary ammonium ion, as well as to a process for production of said compound and uses thereof and to a process for the production of PIR/PUR foam or flexible foam in the presence of the catalyst of the present disclosure.

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MICRO/NANO MATERIALS, PRODUCTS OBTAINED BY COVALENTLY MODIFYING SURFACE OF MICRO/NANO MATERIALS WITH HYDROPHILIC MATERIALS, AND METHOD FOR MAKING SAME
20190077746 · 2019-03-14 ·

Micro-nano materials, products obtained by covalently modifying the surfaces of micro/nano materials with hydrophilic materials, and methods for making the same. The micro/nano materials on the surfaces have carboxyl groups or/and pro-carboxyl groups which are converted into their active esters. The products are covalently modified by forming amide bonds between the active esters on the surfaces and the modification agents; where the modification agents are hydrophilic compounds and/or hydrophilic polymers bearing primary and/or secondary aliphatic amines. Monomers bearing carboxyl groups and/or pro-carboxyl groups are used to produce an adequate number of carboxyl groups and/or pro-carboxyl groups on the surface of a polymer material to be modified. The carboxyl groups and/or pro-carboxyl groups are converted into active esters. A reasonably-sized modification agent bearing primary and/or secondary amines, zwitterions and hydrophilic linear spacer arms is used to form amide bonds and obtain a covalently modified surface layer.

MICRO/NANO MATERIALS, PRODUCTS OBTAINED BY COVALENTLY MODIFYING SURFACE OF MICRO/NANO MATERIALS WITH HYDROPHILIC MATERIALS, AND METHOD FOR MAKING SAME
20190077746 · 2019-03-14 ·

Micro-nano materials, products obtained by covalently modifying the surfaces of micro/nano materials with hydrophilic materials, and methods for making the same. The micro/nano materials on the surfaces have carboxyl groups or/and pro-carboxyl groups which are converted into their active esters. The products are covalently modified by forming amide bonds between the active esters on the surfaces and the modification agents; where the modification agents are hydrophilic compounds and/or hydrophilic polymers bearing primary and/or secondary aliphatic amines. Monomers bearing carboxyl groups and/or pro-carboxyl groups are used to produce an adequate number of carboxyl groups and/or pro-carboxyl groups on the surface of a polymer material to be modified. The carboxyl groups and/or pro-carboxyl groups are converted into active esters. A reasonably-sized modification agent bearing primary and/or secondary amines, zwitterions and hydrophilic linear spacer arms is used to form amide bonds and obtain a covalently modified surface layer.

PROCESS FOR THE PREPARATION OF A QUELATING AGENT
20190002395 · 2019-01-03 ·

It is provided a compound of formula (I); wherein R.sup.5 is selected from the group consisting of H, OM, COOM, NH.sub.2, SO.sub.3M, (C.sub.1-C.sub.4)alkyl, and halogen; and A is a radical having at least 3 C atoms selected from the group consisting of: i) a radical of formula (i) wherein R.sup.7 is selected from the group consisting of OM, and COOM, and n is 0, 1 or 2; and ii) a radical of formula (ii) or of formula (iii) wherein R.sup.8 is selected from the group consisting of H, (C.sub.1-C.sub.4)alkyl; and wherein M is independently selected from the group consisting of H, an alkaly metal, and NH.sub.4.sup.+. It is also provided a process for the preparation thereof, a composition comprising it, and its use for correcting deficiencies of metals in plants.

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