The disclosure provides compounds having formula (I): ##STR00001##
and the pharmaceutically acceptable salts thereof, wherein R.sub.1, R.sub.2, R.sub.2, and X are as defined as set forth in the specification. Compounds having formula (I) are prodrugs that release glutamine analogs, e.g., 6-diazo-5-oxo-L-norleucine (DON). The disclosure also provides compounds having formula (I) for use in treating cancer.

The disclosure provides compounds having formula (I): ##STR00001##
and the pharmaceutically acceptable salts thereof, wherein R.sub.1, R.sub.2, R.sub.2, and X are as defined as set forth in the specification. Compounds having formula (I) are prodrugs that release glutamine analogs, e.g., 6-diazo-5-oxo-L-norleucine (DON). The disclosure also provides compounds having formula (I) for use in treating cancer.

Disclosed is a non-destructive universal method of functionalization of graphitic carbonaceous materials that enables their alignment, cross-linking, and effective integration into composite materials.

Disclosed is a non-destructive universal method of functionalization of graphitic carbonaceous materials that enables their alignment, cross-linking, and effective integration into composite materials.

Disclosed herein are antimicrobial N-Alkyl-N,N-bis(2-carboxyethyl)-N-benzyl ammonium chlorides of Formula I for preservation of home and personal care products. The invention further discloses a process for preparation of the antimicrobial compounds and home & personal care compositions comprising the N-Alkyl-N,N-bis(2-carboxyethyl)-N-benzyl ammonium chlorides of Formula I ##STR00001## R=C.sub.8-18 saturated or unsaturated alkyl group.

Disclosed herein are antimicrobial N-Alkyl-N,N-bis(2-carboxyethyl)-N-benzyl ammonium chlorides of Formula I for preservation of home and personal care products. The invention further discloses a process for preparation of the antimicrobial compounds and home & personal care compositions comprising the N-Alkyl-N,N-bis(2-carboxyethyl)-N-benzyl ammonium chlorides of Formula I ##STR00001## R=C.sub.8-18 saturated or unsaturated alkyl group.

Disclosed herein are antimicrobial N-Alkyl-N,N-bis(2-carboxyethyl)-N-benzyl ammonium chlorides of Formula I for preservation of home and personal care products. The invention further discloses a process for preparation of the antimicrobial compounds and home & personal care compositions comprising the N-Alkyl-N,N-bis(2-carboxyethyl)-N-benzyl ammonium chlorides of Formula I

##STR00001## R=C.sub.8-18 saturated or unsaturated alkyl group

Disclosed herein are antimicrobial N-Alkyl-N,N-bis(2-carboxyethyl)-N-benzyl ammonium chlorides of Formula I for preservation of home and personal care products. The invention further discloses a process for preparation of the antimicrobial compounds and home & personal care compositions comprising the N-Alkyl-N,N-bis(2-carboxyethyl)-N-benzyl ammonium chlorides of Formula I

##STR00001## R=C.sub.8-18 saturated or unsaturated alkyl group

It is provided a compound of formula (I); wherein R.sup.5 is selected from the group consisting of H, OM, COOM, NH.sub.2, SO.sub.3M, (C.sub.1-C.sub.4)alkyl, and halogen; and A is a radical having at least 3 C atoms selected from the group consisting of: i) a radical of formula (i) wherein R.sup.7 is selected from the group consisting of OM, and COOM, and n is 0, 1 or 2; and ii) a radical of formula (ii) or of formula (iii) wherein R.sup.8 is selected from the group consisting of H, (C.sub.1-C.sub.4)alkyl; and wherein M is independently selected from the group consisting of H, an alkaly metal, and NH.sub.4.sup.+. It is also provided a process for the preparation thereof, a composition comprising it, and its use for correcting deficiencies of metals in plants.

##STR00001##

It is provided a compound of formula (I); wherein R.sup.5 is selected from the group consisting of H, OM, COOM, NH.sub.2, SO.sub.3M, (C.sub.1-C.sub.4)alkyl, and halogen; and A is a radical having at least 3 C atoms selected from the group consisting of: i) a radical of formula (i) wherein R.sup.7 is selected from the group consisting of OM, and COOM, and n is 0, 1 or 2; and ii) a radical of formula (ii) or of formula (iii) wherein R.sup.8 is selected from the group consisting of H, (C.sub.1-C.sub.4)alkyl; and wherein M is independently selected from the group consisting of H, an alkaly metal, and NH.sub.4.sup.+. It is also provided a process for the preparation thereof, a composition comprising it, and its use for correcting deficiencies of metals in plants.

##STR00001##