Patent classifications
C07C227/22
SEPARATION OF IMPURITIES IN A PROCESS FOR HYDROLYTICALLY DEPOLYMERIZING A POLYAMIDE
The present invention relates to a process for separating at least one -caprolactam oligomeric compound CPO from a stream S.sub.R comprising said at least one CPO and -caprolactam monomeric compound CPM.
Process for acid hydrolysis of pure polylaurolactam
An improved process can be used for the acid hydrolysis of polylaurolactam with sulfuric acid. An especially suitable starting material is polylaurolactam which is intended for recycling and which is characterized by a low laurolactam content.
Process for acid hydrolysis of pure polylaurolactam
An improved process can be used for the acid hydrolysis of polylaurolactam with sulfuric acid. An especially suitable starting material is polylaurolactam which is intended for recycling and which is characterized by a low laurolactam content.
Process for acid hydrolysis of pure polylaurolactam
An improved process can be used for the acid hydrolysis of polylaurolactam with sulfuric acid. An especially suitable starting material is polylaurolactam which is intended for recycling and which is characterized by a low laurolactam content.
AMINO ACID SURFACTANTS
The present disclosure provides derivatives of amino acids that have surface-active properties. The amino acid can be naturally-occurring or synthetic, or they may be obtained via a ring-opening reaction of a lactam, such as caprolactam. The amino acid may be functionalized to form a compound that is surface-active and have advantageous surfactant characteristics. The compounds of the present disclosure have low critical micelle concentrations (CMC) as well as superior ability to lower the surface tension of a liquid.
AMINO ACID SURFACTANTS
The present disclosure provides derivatives of amino acids that have surface-active properties. The amino acid can be naturally-occurring or synthetic, or they may be obtained via a ring-opening reaction of a lactam, such as caprolactam. The amino acid may be functionalized to form a compound that is surface-active and have advantageous surfactant characteristics. The compounds of the present disclosure have low critical micelle concentrations (CMC) as well as superior ability to lower the surface tension of a liquid.
c-Abl tyrosine kinase inhibitory compound embodiments and methods of making and using the same
Disclosed herein are embodiments of a compound that inhibits c-Abl tyrosine kinase (also referred to herein as c-Abl). The compound embodiments described herein are novel c-Abl inhibitors that can bind to c-Abl at an allosteric site and inhibit its activity in various pathways. The compound embodiments also are capable of crossing the blood brain barrier and therefore are useful in inhibiting c-Abl activity as it affects pathways and/or proteins in the brain. The compound embodiments described herein are effective therapeutic agents for treating diseases involving c-Abl, such as cancers, motor neuron diseases, and neurodegenerative diseases. Also disclosed herein are embodiments of methods for making and using the c-Abl inhibitory compound embodiments.
c-Abl tyrosine kinase inhibitory compound embodiments and methods of making and using the same
Disclosed herein are embodiments of a compound that inhibits c-Abl tyrosine kinase (also referred to herein as c-Abl). The compound embodiments described herein are novel c-Abl inhibitors that can bind to c-Abl at an allosteric site and inhibit its activity in various pathways. The compound embodiments also are capable of crossing the blood brain barrier and therefore are useful in inhibiting c-Abl activity as it affects pathways and/or proteins in the brain. The compound embodiments described herein are effective therapeutic agents for treating diseases involving c-Abl, such as cancers, motor neuron diseases, and neurodegenerative diseases. Also disclosed herein are embodiments of methods for making and using the c-Abl inhibitory compound embodiments.
C-ABL TYROSINE KINASE INHIBITORY COMPOUND EMBODIMENTS AND METHODS OF MAKING AND USING THE SAME
Disclosed herein are embodiments of a compound that inhibits c-Abl tyrosine kinase (also referred to herein as c-Abl). The compound embodiments described herein are novel c-Abl inhibitors that can bind to c-Abl at an allosteric site and inhibit its activity in various pathways. The compound embodiments also are capable of crossing the blood brain barrier and therefore are useful in inhibiting c-Abl activity as it affects pathways and/or proteins in the brain. The compound embodiments described herein are effective therapeutic agents for treating diseases involving c-Abl, such as cancers, motor neuron diseases, and neurodegenerative diseases. Also disclosed herein are embodiments of methods for making and using the c-Abl inhibitory compound embodiments.
C-ABL TYROSINE KINASE INHIBITORY COMPOUND EMBODIMENTS AND METHODS OF MAKING AND USING THE SAME
Disclosed herein are embodiments of a compound that inhibits c-Abl tyrosine kinase (also referred to herein as c-Abl). The compound embodiments described herein are novel c-Abl inhibitors that can bind to c-Abl at an allosteric site and inhibit its activity in various pathways. The compound embodiments also are capable of crossing the blood brain barrier and therefore are useful in inhibiting c-Abl activity as it affects pathways and/or proteins in the brain. The compound embodiments described herein are effective therapeutic agents for treating diseases involving c-Abl, such as cancers, motor neuron diseases, and neurodegenerative diseases. Also disclosed herein are embodiments of methods for making and using the c-Abl inhibitory compound embodiments.