Patent classifications
C07C227/36
Compound, optical resolution method, and derivative of an optical isomer of an amino acid
Disclosed is a compound represented by chemical formula (1): ##STR00001##
or chemical formula (2): ##STR00002##
Compound, optical resolution method, and derivative of an optical isomer of an amino acid
Disclosed is a compound represented by chemical formula (1): ##STR00001##
or chemical formula (2): ##STR00002##
Process for the racemization of α-amino acids
According to the present invention, a method is provided wherein a basic aqueous phase containing an optically active -amino acid is brought into contact with an organic phase containing a racemisation catalyst in the form of a copper metal complex of copper ions and an -amino acid and salicylaldehyde, in the presence of a phase transition catalyst, thereby subjecting the optically active -amino acid to racemisation. In the -amino acid racemisation method according to the present invention, the reaction conditions are mild and thus there is little -amino acid breakdown and the yield is high, the racemisation catalyst can be reused, the -amino acid resulting from the racemisation can easily be isolated and purified, and the racemisation method can be implemented in volume such that the invention is economic.
Process for the racemization of α-amino acids
According to the present invention, a method is provided wherein a basic aqueous phase containing an optically active -amino acid is brought into contact with an organic phase containing a racemisation catalyst in the form of a copper metal complex of copper ions and an -amino acid and salicylaldehyde, in the presence of a phase transition catalyst, thereby subjecting the optically active -amino acid to racemisation. In the -amino acid racemisation method according to the present invention, the reaction conditions are mild and thus there is little -amino acid breakdown and the yield is high, the racemisation catalyst can be reused, the -amino acid resulting from the racemisation can easily be isolated and purified, and the racemisation method can be implemented in volume such that the invention is economic.