Soluble chelator-compounds, methods for their production and their use for the modification and/or immobilization of target molecules.

Soluble chelator-compounds, methods for their production and their use for the modification and/or immobilization of target molecules.

The invention relates to a method for producing a composition containing at least one metal amino acid compound, in which methoda basic compound of a divalent metal is first reacted together with an alpha amino acid in a molar relationship of one to at least two in water during heating of up to 60? C. to 100? C.,a reaction equilibrium is awaited,the reaction solution is then mixed with a water-soluble salt of the same divalent metal at a quantity such that the molar total quantity of the divalent metal from the basic compound of the metal and the metal salt does not exceed the molar quantity of the alpha amino acid,the metal salt is allowed to completely dissolve,the reaction solution is then dried thereby obtaining a solid composition.

The invention relates to a method for producing a composition containing at least one metal amino acid compound, in which methoda basic compound of a divalent metal is first reacted together with an alpha amino acid in a molar relationship of one to at least two in water during heating of up to 60? C. to 100? C.,a reaction equilibrium is awaited,the reaction solution is then mixed with a water-soluble salt of the same divalent metal at a quantity such that the molar total quantity of the divalent metal from the basic compound of the metal and the metal salt does not exceed the molar quantity of the alpha amino acid,the metal salt is allowed to completely dissolve,the reaction solution is then dried thereby obtaining a solid composition.

The invention comprises a process and composition relating to the use of an artificial blood that is a pharmaceutically acceptable solution of an iron amino acid chelate. In a preferred embodiment of the invention, the amino acid chelate is formed from a glycinate from pyridine or a bis pyridine. In use, the amino acid chelate is dissolved in a suitable carrier fluid such as an isotonic saline solution and transfused into an individual suffering trauma from loss of blood.

The invention comprises a process and composition relating to the use of an artificial blood that is a pharmaceutically acceptable solution of an iron amino acid chelate. In a preferred embodiment of the invention, the amino acid chelate is formed from a glycinate from pyridine or a bis pyridine. In use, the amino acid chelate is dissolved in a suitable carrier fluid such as an isotonic saline solution and transfused into an individual suffering trauma from loss of blood.

The disclosure provides metal complexes which have improved stability in the presence of humidity. The disclosure also provides a method of making metal complexes and uses thereof.

The disclosure provides metal complexes which have improved stability in the presence of humidity. The disclosure also provides a method of making metal complexes and uses thereof.

The disclosure provides metal complexes which have improved stability in the presence of humidity. The disclosure also provides a method of making metal complexes and uses thereof.

Described herein are multi-dimensional networks that can include a recurring unit of Formula (I) and a recurring unit of Formula (II), and methods of synthesizing and using the same.