The present disclosure relates to a new type of vortioxetine analogue of Formula I or its polymorph or a solvate, a composition, and a kit comprising the analogue, the polymorph or the solvate, and the use of the compound or the polymorph or the solvate, or the composition in the preparation of a medicament for the treatment of depression. The methods of preparation of the analogues and intermediate compounds are also described.

##STR00001##

A polythiol composition according to exemplary embodiments includes a main polythiol compound and a sub-compound having a molecular weight higher than that of the main polythiol compound. A peak area (%) at retention times ranging from 34 to 40 minutes in the high performance liquid chromatography (HPLC) analysis graph obtained at a wavelength of 230 nm, which corresponds to the sub-compound, is 2.5% or less. An optical product having improved transmittance and optical properties may be manufactured through fine adjustment of the sub-compound.

A polythiol composition according to exemplary embodiments includes a main polythiol compound and a sub-compound having a molecular weight higher than that of the main polythiol compound. A peak area (%) at retention times ranging from 34 to 40 minutes in the high performance liquid chromatography (HPLC) analysis graph obtained at a wavelength of 230 nm, which corresponds to the sub-compound, is 2.5% or less. An optical product having improved transmittance and optical properties may be manufactured through fine adjustment of the sub-compound.

The purpose of the present invention is to provide: novel thiol compounds; a method for synthesizing said thiol compounds; curing agents containing said thiol compounds; resin compositions containing said thiol compounds and an epoxy compound; and resin compositions containing said thiol compounds and an ene compound having a carbon-carbon double bond in a molecule. Furthermore, the purpose of the present invention is to provide adhesives and sealants having these resin compositions as ingredients. The thiol compounds of the present invention are represented by chemical formula (I) to chemical formula (VII).

The purpose of the present invention is to provide: novel thiol compounds; a method for synthesizing said thiol compounds; curing agents containing said thiol compounds; resin compositions containing said thiol compounds and an epoxy compound; and resin compositions containing said thiol compounds and an ene compound having a carbon-carbon double bond in a molecule. Furthermore, the purpose of the present invention is to provide adhesives and sealants having these resin compositions as ingredients. The thiol compounds of the present invention are represented by chemical formula (I) to chemical formula (VII).

The invention relates to a process for preparing methyl mercaptan from a mixture of carbon oxide, hydrogen sulfide and hydrogen, in the presence of a catalyst based on molybdenum and potassium supported on zirconia, said catalyst not comprising any promoter.

The invention relates to a process for preparing methyl mercaptan from a mixture of carbon oxide, hydrogen sulfide and hydrogen, in the presence of a catalyst based on molybdenum and potassium supported on zirconia, said catalyst not comprising any promoter.

The present invention relates to a method for preparing methyl mercaptan, in batches or continuously, preferably continuously, said method including at least the following steps: a) reacting at least one hydrocarbon feedstock in the presence of hydrogen sulphide (H.sub.2S) and optionally sulphur (S) such as to form carbon disulphide (CS.sub.2) and hydrogen (H.sub.2); b) reacting said carbon disulphide (CS.sub.2) by hydrogenation in the presence of said hydrogen (H.sub.2) obtained in step a) such as to form methyl mercaptan (CH.sub.3SH), hydrogen sulphide (H.sub.2S) and possibly hydrogen (H.sub.2); c) optionally recirculating said hydrogen sulphide (H.sub.2S) formed during step b) to step a); and d) recovering the methyl mercaptan.

The present invention relates to a method for preparing methyl mercaptan, in batches or continuously, preferably continuously, said method including at least the following steps: a) reacting at least one hydrocarbon feedstock in the presence of hydrogen sulphide (H.sub.2S) and optionally sulphur (S) such as to form carbon disulphide (CS.sub.2) and hydrogen (H.sub.2); b) reacting said carbon disulphide (CS.sub.2) by hydrogenation in the presence of said hydrogen (H.sub.2) obtained in step a) such as to form methyl mercaptan (CH.sub.3SH), hydrogen sulphide (H.sub.2S) and possibly hydrogen (H.sub.2); c) optionally recirculating said hydrogen sulphide (H.sub.2S) formed during step b) to step a); and d) recovering the methyl mercaptan.

The present invention relates to a method for preparing methyl mercaptan, in batches or continuously, preferably continuously, said method including at least the following steps: a) reacting at least one hydrocarbon feedstock in the presence of hydrogen sulphide (H.sub.2S) and optionally sulphur (S) such as to form carbon disulphide (CS.sub.2) and hydrogen (H.sub.2); b) reacting said carbon disulphide (CS.sub.2) by hydrogenation in the presence of said hydrogen (H.sub.2) obtained in step a) such as to form methyl mercaptan (CH.sub.3SH), hydrogen sulphide (H.sub.2S) and possibly hydrogen (H.sub.2); c) optionally recirculating said hydrogen sulphide (H.sub.2S) formed during step b) to step a); and d) recovering the methyl mercaptan.