Provided is a method of preparing an N-acetyl dipeptide and an N-acetyl amino acid, the method including producing the N-acetyl dipeptide and the N-acetyl amino acid by reaction of an amino acid with acetic anhydride or acetyl chloride.

Provided is a method of preparing an N-acetyl dipeptide and an N-acetyl amino acid, the method including producing the N-acetyl dipeptide and the N-acetyl amino acid by reaction of an amino acid with acetic anhydride or acetyl chloride.

Methods for using sulfur-containing compounds comprising short chain aliphatic ester or amide moieties as solvents and compositions comprising these compounds are provided.

Methods for using sulfur-containing compounds comprising short chain aliphatic ester or amide moieties as solvents and compositions comprising these compounds are provided.

Methods for using sulfur-containing compounds comprising short chain aliphatic ester or amide moieties as solvents and compositions comprising these compounds are provided.

The invention relates to the manufacture of certain polyunsaturated compounds employing a particular application of the Mitsonobu reaction in the presence of at least one anti-oxidant. We have found a method of making a pharmaceutically-acceptable polyunsaturated ester or thioester compound directly, which can ultimately be converted to the advantageous ketone compounds, in which unwanted oxidation and cis/trans isomerization are substantially reduced or eliminated using particular Mitsonobu chemistry.

The invention relates to the manufacture of certain polyunsaturated compounds employing a particular application of the Mitsonobu reaction in the presence of at least one anti-oxidant. We have found a method of making a pharmaceutically-acceptable polyunsaturated ester or thioester compound directly, which can ultimately be converted to the advantageous ketone compounds, in which unwanted oxidation and cis/trans isomerization are substantially reduced or eliminated using particular Mitsonobu chemistry.

Disclosed is to prevent generation of byproducts or a deterioration in the physical properties of a polythiol composition that may be caused by active oxygen during storage thereof by way of controlling the content of active oxygen in the polythiol composition after the synthesis of the polythiol. As a result, it is possible to enhance the long-term storage stability of a polythiol composition after it has been synthesized until it is used in the polymerization reaction.

Disclosed is to prevent generation of byproducts or a deterioration in the physical properties of a polythiol composition that may be caused by active oxygen during storage thereof by way of controlling the content of active oxygen in the polythiol composition after the synthesis of the polythiol. As a result, it is possible to enhance the long-term storage stability of a polythiol composition after it has been synthesized until it is used in the polymerization reaction.

Disclosed is to prevent generation of byproducts or a deterioration in the physical properties of a polythiol composition that may be caused by active oxygen during storage thereof by way of controlling the content of active oxygen in the polythiol composition after the synthesis of the polythiol. As a result, it is possible to enhance the long-term storage stability of a polythiol composition after it has been synthesized until it is used in the polymerization reaction.