Patent classifications
C07C403/04
Process for preparing chiral 2,3-dihydrothiazolo[3,2-A] pyrimidin-4-ium compounds
The present invention relates to a process for preparing optically active compounds of formula X and intermediates thereof, ##STR00001##
wherein the variables of compound of formula X are as defined in the claims and the description.
Process for preparing chiral 2,3-dihydrothiazolo[3,2-A] pyrimidin-4-ium compounds
The present invention relates to a process for preparing optically active compounds of formula X and intermediates thereof, ##STR00001##
wherein the variables of compound of formula X are as defined in the claims and the description.
Triazole n-linked carbamoyl cyclohexyl acids as LPA antagonists
The present invention provides compounds of Formula (I): ##STR00001##
or a stereoisomer, tautomer, or pharmaceutically acceptable salt or solvate thereof, wherein all the variables are as defined herein. These compounds are selective LPA receptor inhibitors.
Triazole n-linked carbamoyl cyclohexyl acids as LPA antagonists
The present invention provides compounds of Formula (I): ##STR00001##
or a stereoisomer, tautomer, or pharmaceutically acceptable salt or solvate thereof, wherein all the variables are as defined herein. These compounds are selective LPA receptor inhibitors.
PROCESS FOR PREPARING CHIRAL 2,3-DIHYDROTHIAZOLO[3,2-A]PYRIMIDIN-4-IUM COMPOUNDS
The present invention relates to a process for preparing optically active compounds of formula X and intermediates thereof,
##STR00001##
wherein the variables of compound of formula X are as defined in the claims and the description.
Triazole N-linked carbamoyl cyclohexyl acids as LPA antagonists
The present invention provides compounds of Formula (I): ##STR00001##
or a stereoisomer, tautomer, or pharmaceutically acceptable salt or solvate thereof, wherein all the variables are as defined herein. These compounds are selective LPA receptor inhibitors.
Triazole N-linked carbamoyl cyclohexyl acids as LPA antagonists
The present invention provides compounds of Formula (I): ##STR00001##
or a stereoisomer, tautomer, or pharmaceutically acceptable salt or solvate thereof, wherein all the variables are as defined herein. These compounds are selective LPA receptor inhibitors.
TRIAZOLE N-LINKED CARBAMOYL CYCLOHEXYL ACIDS AS LPA ANTAGONISTS
The present invention provides compounds of Formula (I):
##STR00001##
or a stereoisomer, tautomer, or pharmaceutically acceptable salt or solvate thereof, wherein all the variables are as defined herein. These compounds are selective LPA receptor inhibitors.
METHODS AND COMPOSITIONS FOR TREATING ATOPIC DERMATITIS
The present invention provides methods and compositions for treating atopic dermatitis by cyclohexenone compounds.
TRIAZOLE N-LINKED CARBAMOYL CYCLOHEXYL ACIDS AS LPA ANTAGONISTS
The present invention provides compounds of Formula (I):
##STR00001##
or a stereoisomer, tautomer, or pharmaceutically acceptable salt or solvate thereof, wherein all the variables are as defined herein. These compounds are selective LPA receptor inhibitors.