C07C403/14

Process of production of 7,8-dihydro-C15-aldehyde

The present invention relates to a new method to produce 7,8-dihydro-C.sub.15-aldehyde.

Process of production of 7,8-dihydro-C15-aldehyde

The present invention relates to a new method to produce 7,8-dihydro-C.sub.15-aldehyde.

Compounds for the treatment of HIV

The invention provides compounds of formula (I): or a salt thereof as described herein. The invention also provides pharmaceutical compositions comprising a compound of formula (I), processes for preparing compounds of formula (I), intermediates useful for preparing compounds of formula I and therapeutic methods for treating a Retroviridae viral infection including an infection caused by the HIV virus. ##STR00001##

Process for the production of retinal

The present invention relates to a new process for the production of retinal or hydrogenated form of retinal.

Process for the production of retinal

The present invention relates to a new process for the production of retinal or hydrogenated form of retinal.

Method for producing specific α,β-unsaturated aldehydes by rearrangement process

The present invention relates to an improved method for producing specific ,-unsaturated aldehydes.

Method for producing specific α,β-unsaturated aldehydes by rearrangement process

The present invention relates to an improved method for producing specific ,-unsaturated aldehydes.

N-pyrrolidinyl,N′-pyrazolyl-urea, thiourea, guanidine and cyanoguanidine compounds as TrkA kinase inhibitors

Compounds of Formula (I) or stereoisomers, tautomers, or pharmaceutically acceptable salts, or solvates or prodrugs thereof, where R.sup.1, R.sup.2, R.sup.a, R.sup.b, R.sup.c, R.sup.d, X, Ring B, and Ring C are as defined herein, and wherein Ring B and the NHC(?X)NH moiety are in the trans configuration, are inhibitors of TrkA kinase and are useful in the treatment of diseases which can be treated with a TrkA kinase inhibitor such as pain, cancer, inflammation/inflammatory diseases, neurodegenerative diseases, certain infectious diseases, Sjogren's syndrome, endometriosis, diabetic peripheral neuropathy, prostatitis or pelvic pain syndrome. ##STR00001##

Triazolone derivatives or salts thereof and pharmaceutical composition comprising the same

Provided is a triazolone derivative or its pharmaceutically acceptable salt, a process for the preparation thereof, and a pharmaceutical composition comprising the same. The triazolone derivative or its pharmaceutically acceptable salt can effectively activate GPR119; and therefore be usefully applied for preventing or treating diabetes mellitus.

COMPOUNDS FOR THE TREATMENT OF HIV

The invention provides compounds of formula (I): or a salt thereof as described herein. The invention also provides pharmaceutical compositions comprising a compound of formula (I), processes for preparing compounds of formula (I), intermediates useful for preparing compounds of formula I and therapeutic methods for treating a Retroviridae viral infection including an infection caused by the HIV virus.

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