Methods for preparing isotopically modified 1,4-diene systems from non-isotopically modified 1,4-dienes involve selective oxidation of one or more bis-allylic position(s), or the preparation of isotopically modified 1,4-diene systems via trapping pi-allylic complexes with a source of deuterium or tritium. Such methods are useful for preparing isotopically modified polyunsaturated lipid including polyunsaturated fatty acids and polyunsaturated fatty acid derivatives.

Methods for preparing isotopically modified 1,4-diene systems from non-isotopically modified 1,4-dienes involve selective oxidation of one or more bis-allylic position(s), or the preparation of isotopically modified 1,4-diene systems via trapping pi-allylic complexes with a source of deuterium or tritium. Such methods are useful for preparing isotopically modified polyunsaturated lipid including polyunsaturated fatty acids and polyunsaturated fatty acid derivatives.

Methods for preparing isotopically modified 1,4-diene systems from non-isotopically modified 1,4-dienes involve selective oxidation of one or more bis-allylic position(s), or the preparation of isotopically modified 1,4-diene systems via trapping pi-allylic complexes with a source of deuterium or tritium. Such methods are useful for preparing isotopically modified polyunsaturated lipid including polyunsaturated fatty acids and polyunsaturated fatty acid derivatives.

The invention relates to a composition obtained by the adsorption of a liquid peroxide onto granules comprising an antioxidant and an acid scavenger, for example wherein the adsorption of the liquid peroxide onto the granules is performed by a process which can be performed at room temperature (23° C.) and the process does not require heating.

The invention relates to a composition obtained by the adsorption of a liquid peroxide onto granules comprising an antioxidant and an acid scavenger, for example wherein the adsorption of the liquid peroxide onto the granules is performed by a process which can be performed at room temperature (23° C.) and the process does not require heating.

The invention relates to a composition obtained by the adsorption of a liquid peroxide onto granules comprising an antioxidant and an acid scavenger, for example wherein the adsorption of the liquid peroxide onto the granules is performed by a process which can be performed at room temperature (23° C.) and the process does not require heating.

The invention relates to a composition obtained by the adsorption of a liquid peroxide onto granules comprising an antioxidant and an acid scavenger, for example wherein the adsorption of the liquid peroxide onto the granules is performed by a process which can be performed at room temperature (23° C.) and the process does not require heating.

Methods for preparing isotopically modified 1,4-diene systems from non-isotopically modified 1,4-dienes involve selective oxidation of one or more bis-allylic position(s), or the preparation of isotopically modified 1,4-diene systems via trapping pi-allylic complexes with a source of deuterium or tritium. Such methods are useful for preparing isotopically modified polyunsaturated lipid including polyunsaturated fatty acids and polyunsaturated fatty acid derivatives.

Methods for preparing isotopically modified 1,4-diene systems from non-isotopically modified 1,4-dienes involve selective oxidation of one or more bis-allylic position(s), or the preparation of isotopically modified 1,4-diene systems via trapping pi-allylic complexes with a source of deuterium or tritium. Such methods are useful for preparing isotopically modified polyunsaturated lipid including polyunsaturated fatty acids and polyunsaturated fatty acid derivatives.

The present invention relates to the preparation of perfluorinated or partially fluorinated peroxides which avoids the use of carbonyl fluoride (COF.sub.2).