The present invention relates to new cinnamic add amides which may be used for treatment of fibrosis and neoplasia and to cinnamic acid amides for use in the treatment of fibrosis, neoplasia, arthrolithiasis, familiar mediterranean fever and pericarditis. Further, the invention relates to a pharmaceutical composition comprising said cinnamic acid amides and to a screening essay for identifying compounds suitable for the treatment of fibrosis.

The present invention relates to new cinnamic add amides which may be used for treatment of fibrosis and neoplasia and to cinnamic acid amides for use in the treatment of fibrosis, neoplasia, arthrolithiasis, familiar mediterranean fever and pericarditis. Further, the invention relates to a pharmaceutical composition comprising said cinnamic acid amides and to a screening essay for identifying compounds suitable for the treatment of fibrosis.

A method for forming a film for the fabrication of a microelectronic or optoelectronic device comprising a series of diazirine compounds of formula (I) having utility as photocrosslinkers are disclosed.

##STR00001##

Where, A, L, z, Ar.sub.x and R.sub.y are as defined herein.

A method for forming a film for the fabrication of a microelectronic or optoelectronic device comprising a series of diazirine compounds of formula (I) having utility as photocrosslinkers are disclosed.

##STR00001##

Where, A, L, z, Ar.sub.x and R.sub.y are as defined herein.

Provided herein are photocrosslinking reagents, crosslinkable proteins displaying photocrosslinking groups, crosslinked protein-protein complexes, and methods of use thereof.

Provided herein are photocrosslinking reagents, crosslinkable proteins displaying photocrosslinking groups, crosslinked protein-protein complexes, and methods of use thereof.

A series of diazirine compounds of formula (I) having utility as photocrosslinkers are disclosed. ##STR00001##
Where, A, L, z, Ar.sub.x and R.sub.y are as defined herein. Also disclosed are the photodefinable compositions containing these compounds.

A series of diazirine compounds of formula (I) having utility as photocrosslinkers are disclosed. ##STR00001##
Where, A, L, z, Ar.sub.x and R.sub.y are as defined herein. Also disclosed are the photodefinable compositions containing these compounds.

The present invention refers to novel UV-light cleavable drug conjugates comprising a diazirine linker.

This disclosure relates to compounds, pharmaceutical compositions comprising them, and methods of using the compounds and compositions for treating diseases related to Heat Shock Transcription Factor 1 (HSF1) activity and/or function. More particularly, this disclosure relates to methods of inhibiting HSF1 activity with these compounds and pharmaceutical compositions thereof, and methods of treating diseases associated with HSF1 activity and/or function, such as cancer.