Patent classifications
C07D261/20
COMPOUNDS FOR THE TREATMENT OF PARAMYXOVIRUS VIRAL INFECTIONS
Disclosed herein are new antiviral compounds, together with pharmaceutical compositions that include one or more antiviral compounds, and methods of synthesizing the same. Also disclosed herein are methods of ameliorating and/or treating a paramyxovirus viral infection with one or more small molecule compounds. Examples of paramyxovirus infection include an infection caused by human respiratory syncytial virus (RSV).
NOVEL HYDRAZONE DERIVATIVE IN WHICH TERMINAL AMINE GROUP IS SUBSTITUTED WITH ARYL GROUP OR HETEROARYL GROUP, AND USE THEREOF
- Ae Nim Pae ,
- Yun Kyung Kim ,
- Sang Min LIM ,
- Sungsu LIM ,
- Jihye SEONG ,
- Jae Wook Lee ,
- Ji Yeon Song ,
- Seulgi SHIN ,
- Hyean Jeong JEONG ,
- Woo Seung SON ,
- Haeun LEE ,
- Da Mi LIM ,
- Seok Kyu KIM ,
- Jee Yun AHN ,
- Chae Won KIM ,
- Ashwini Machhindra LONDHE ,
- Lizaveta GOTINA ,
- Hyojin KIM ,
- Hye Yeon LEE ,
- Nam Gyung KIM ,
- Eunji CHA ,
- Kunhee KIM ,
- Ji Woong LIM
The present invention relates to novel hydrazone derivatives in which a terminal amine group is substituted with an aryl group or a heteroaryl group, and uses thereof.
SSAO inhibitor
The present invention provides an SSAO inhibitor and an application thereof in preparing a drug for treating a disease related to SSAO. In particular, the present invention provides a compound shown in formula (IV) and a pharmaceutically acceptable salt thereof. ##STR00001##
SSAO inhibitor
The present invention provides an SSAO inhibitor and an application thereof in preparing a drug for treating a disease related to SSAO. In particular, the present invention provides a compound shown in formula (IV) and a pharmaceutically acceptable salt thereof. ##STR00001##
MODULATORS OF THE INTEGRATED STRESS PATHWAY
Provided herein are compounds, compositions, and methods useful for modulating the integrated stress response (ISR) and for treating related diseases; disorders and conditions.
MODULATORS OF THE INTEGRATED STRESS PATHWAY
Provided herein are compounds, compositions, and methods useful for modulating the integrated stress response (ISR) and for treating related diseases; disorders and conditions.
METHOD FOR PRODUCING AROMATIC ASTATINE COMPOUND
This method for producing an aromatic astatine compound comprises reacting an aromatic iodonium ylide with astatine to produce an aromatic astatine compound.
METHOD FOR PRODUCING AROMATIC ASTATINE COMPOUND
This method for producing an aromatic astatine compound comprises reacting an aromatic iodonium ylide with astatine to produce an aromatic astatine compound.
Amide prodrugs of small molecule nuclear receptor modulators
Provided herein are novel amide prodrug forms of pharmaceutically active agents useful for central nervous system disorders.
Amide prodrugs of small molecule nuclear receptor modulators
Provided herein are novel amide prodrug forms of pharmaceutically active agents useful for central nervous system disorders.