C07D263/52

Aminocyclobutanes as monoacylglycerol lipase modulators

Aminocyclobutane compounds of Formula (I), and pharmaceutically acceptable salts, isotopes, N-oxides, solvates, and stereoisomers thereof, pharmaceutical compositions containing them, and methods of using them including methods for treating disease states, disorders, and conditions associated with MGL modulation, such as those associated with pain, psychiatric disorders, neurological disorders (including, but not limited to major depressive disorder, treatment resistant depression, anxious depression, autism spectrum disorders, Asperger syndrome, bipolar disorder), cancers and eye conditions: ##STR00001##
wherein X, R.sup.1, R.sup.2a, R.sup.2b, R.sup.3 and R.sup.4 are defined herein.

Aminocyclobutanes as monoacylglycerol lipase modulators

Aminocyclobutane compounds of Formula (I), and pharmaceutically acceptable salts, isotopes, N-oxides, solvates, and stereoisomers thereof, pharmaceutical compositions containing them, and methods of using them including methods for treating disease states, disorders, and conditions associated with MGL modulation, such as those associated with pain, psychiatric disorders, neurological disorders (including, but not limited to major depressive disorder, treatment resistant depression, anxious depression, autism spectrum disorders, Asperger syndrome, bipolar disorder), cancers and eye conditions: ##STR00001##
wherein X, R.sup.1, R.sup.2a, R.sup.2b, R.sup.3 and R.sup.4 are defined herein.

Organic electroluminescent compound and organic electroluminescent device comprising the same

The present disclosure relates to an organic electroluminescent compound and an organic electroluminescent device comprising the same. The organic electroluminescent compound according to the present disclosure is contained in an electron transport layer and/or an electron buffer layer, so that an organic electroluminescent device having improved light-emitting efficiency can be manufactured.

Method of fixating carbon dioxide to substituted oxazolidinones

A method of fixating carbon dioxide (CO.sub.2) to a substituted oxazolidinone. The method includes mixing a metal-organic framework (MOF), a co-catalyst, at least one para-substituted aromatic amine, and at least one epoxide to form a mixture. The method further includes contacting the mixture with a gas stream containing CO.sub.2 to react the CO.sub.2 in the gas stream with the epoxide and para-substituted aromatic amine to form a substituted oxazolidinone mixture. The MOF is a UiO-66-X MOF, where X is of formula (I) wherein at least one of R.sup.1 to R.sup.4 is an allyloxy group, and R.sup.1 to R.sup.4 are independently an allyloxy group or a hydrogen. ##STR00001##

Method of fixating carbon dioxide to substituted oxazolidinones

A method of fixating carbon dioxide (CO.sub.2) to a substituted oxazolidinone. The method includes mixing a metal-organic framework (MOF), a co-catalyst, at least one para-substituted aromatic amine, and at least one epoxide to form a mixture. The method further includes contacting the mixture with a gas stream containing CO.sub.2 to react the CO.sub.2 in the gas stream with the epoxide and para-substituted aromatic amine to form a substituted oxazolidinone mixture. The MOF is a UiO-66-X MOF, where X is of formula (I) wherein at least one of R.sup.1 to R.sup.4 is an allyloxy group, and R.sup.1 to R.sup.4 are independently an allyloxy group or a hydrogen. ##STR00001##

TRIPHENYLENE DERIVATIVES FOR USE IN IMAGING BIOLOGICAL TISSUE OR FLUID

A composition for imaging a biological tissue or fluid comprising a compound of formula (A) and a biologically acceptable diluent or carrier, (A) wherein X represents one of a nitrogen atom, an oxygen atom, a sulphur atom, a phosphorus atom, or a selenium atom; R represents an aromatic group and/or an aliphatic group; p is an integer of 1 to 2; q and s are independently integers of 1, 2, 3, or 4; Y.sup.1, Y.sup.2, and Y.sup.3 independently represent a hydrogen atom, a deuterium atom, a fluorine atom, a chlorine atom, a bromine atom, a substituted or unsubstituted alkyl group, a substituted or unsubstituted aryl group, a polyglycol group, an oxygen atom, a nitrogen atom, a cyano group, a nitro group; and/or wherein two or more of Y.sup.1, Y.sup.2, and Y.sup.3 may combine together to form a condensed ring.

##STR00001##

COMPOUNDS FOR PROVIDING A LONG-LASTING ODOR
20230091481 · 2023-03-23 ·

The present invention relates to the field of perfumery. More particularly, it relates to compounds of formula (I) that are able to provide a long-lasting or substantive odor to the environment. Moreover, the present invention relates to a method of imparting a long-lasting odor to environment or to surfaces, such as hard surfaces, fabric, skin or hair. Furthermore, the present invention relates to the use of said compounds in perfumery, as well as the perfuming compositions or perfumed articles comprising the invention’s compounds.

COMPOUNDS FOR PROVIDING A LONG-LASTING ODOR
20230091481 · 2023-03-23 ·

The present invention relates to the field of perfumery. More particularly, it relates to compounds of formula (I) that are able to provide a long-lasting or substantive odor to the environment. Moreover, the present invention relates to a method of imparting a long-lasting odor to environment or to surfaces, such as hard surfaces, fabric, skin or hair. Furthermore, the present invention relates to the use of said compounds in perfumery, as well as the perfuming compositions or perfumed articles comprising the invention’s compounds.

ORGANIC MATERIAL COMPOSITION AND APPLICATIONS THEREOF
20230157161 · 2023-05-18 ·

The present invention provides an organic material composition and applications thereof. By the combination of the compounds comprised in the organic material composition, the organic material composition makes the element have a lower driving voltage, a higher current efficiency and a longer service life.

ORGANIC MATERIAL COMPOSITION AND APPLICATIONS THEREOF
20230157161 · 2023-05-18 ·

The present invention provides an organic material composition and applications thereof. By the combination of the compounds comprised in the organic material composition, the organic material composition makes the element have a lower driving voltage, a higher current efficiency and a longer service life.