C07D273/01

Pharmaceutical composition for preventing or treating cancer

Exemplary embodiments relate to a novel anticancer composition including a compound represented by chemical formula 1 or pharmaceutically acceptable salt thereof as an active ingredient: ##STR00001##

Pharmaceutical composition for preventing or treating cancer

Exemplary embodiments relate to a novel anticancer composition including a compound represented by chemical formula 1 or pharmaceutically acceptable salt thereof as an active ingredient: ##STR00001##

AN OXAZIRIDINE PLATFORM FOR TARGETING FUNCTIONAL ALLOSTERIC METHIONINE SITES

The present disclosure features compounds (e.g., oxaziridine-based compounds), as well as related compositions and methods of use thereof, e.g., for selectively labeling a methionine residue in a target peptide or protein.

AN OXAZIRIDINE PLATFORM FOR TARGETING FUNCTIONAL ALLOSTERIC METHIONINE SITES

The present disclosure features compounds (e.g., oxaziridine-based compounds), as well as related compositions and methods of use thereof, e.g., for selectively labeling a methionine residue in a target peptide or protein.

Synthesis of heterocyclic compounds from carboxamide and carboxamide derivatives with haloalkanols

The invention provides for methods for the synthesis of various compounds through reaction of carboxamide, or carboxamide derivatives, with various substituted or unsubstituted haloalkanols in a one-step, single vessel, reaction mechanism. Preferably, but not exclusively, the reaction proceeds in the absence of any solvents, catalyst, base, or any further reagents.

Synthesis of heterocyclic compounds from carboxamide and carboxamide derivatives with haloalkanols

The invention provides for methods for the synthesis of various compounds through reaction of carboxamide, or carboxamide derivatives, with various substituted or unsubstituted haloalkanols in a one-step, single vessel, reaction mechanism. Preferably, but not exclusively, the reaction proceeds in the absence of any solvents, catalyst, base, or any further reagents.

Heterocyclic GLP-1 agonists

This disclosure relates to GLP-1 agonists of Formula I: ##STR00001##
including pharmaceutically acceptable salts and solvates thereof, and pharmaceutical compositions including the same.

Heterocyclic GLP-1 agonists

This disclosure relates to GLP-1 agonists of Formula I: ##STR00001##
including pharmaceutically acceptable salts and solvates thereof, and pharmaceutical compositions including the same.

HETEROCYCLIC GLP-1 AGONISTS
20260055069 · 2026-02-26 ·

This disclosure relates to GLP-1 agonists of Formula I.

##STR00001##

including pharmaceutically acceptable salts and solvates thereof, and pharmaceutical compositions including the same.

HETEROCYCLIC GLP-1 AGONISTS
20260055069 · 2026-02-26 ·

This disclosure relates to GLP-1 agonists of Formula I.

##STR00001##

including pharmaceutically acceptable salts and solvates thereof, and pharmaceutical compositions including the same.