The present invention relates to compounds of formula (I). The compounds may be used to modulate the Stimulator of Interferon Genes (STING) protein and thereby treat diseases such as cancer and microbial infections.

##STR00001##

The present disclosure relates to compounds, which are useful for regulating the expression of apolipoprotein A-I (ApoA-I), and their use for treatment and prevention of cardiovascular disease and related disease states, including cholesterol- or lipid-related disorders, such as, for example, atherosclerosis.

The present disclosure relates to compounds, which are useful for regulating the expression of apolipoprotein A-I (ApoA-I), and their use for treatment and prevention of cardiovascular disease and related disease states, including cholesterol- or lipid-related disorders, such as, for example, atherosclerosis.

Disclosed are compounds, compositions, and methods useful for treating neuronal and mitochondrial diseases.

Disclosed are compounds, compositions, and methods useful for treating neuronal and mitochondrial diseases.

Disclosed are compounds, compositions, and methods useful for treating neuronal and mitochondrial diseases.

Disclosed are compounds, compositions, and methods useful for treating neuronal and mitochondrial diseases.

Disclosed are compounds, compositions, and methods useful for treating neuronal and mitochondrial diseases.

Disclosed are compounds, compositions, and methods useful for treating neuronal and mitochondrial diseases.

The invention relates to an organic molecule having precisely two units of formula I linked to one another via a single bond or a bridge Y ##STR00001## where Y=a divalent group; X=at each occurrence identically or differently CN and CF.sub.3; D=chemical unit having a structure of the formula I-1: ##STR00002## where #=attachment point of the unit of formula I-1 to the structure of formula I; A and B=independently of one another are selected from the group consisting of CRR.sup.1, CR, NR, N, there being a single or double bond between A and B and a single or double bond between B and Z; Z=a direct bond or a divalent organic bridge which is a substituted or unsubstituted C1-C9-alkylene, C2-C8-alkenylene, C2-C8-alkynylene or arylene group or a combination thereof, CRR.sup.1, CCRR.sup.1, CNR, NR, O, SiRR.sup.1, S, S(O), S(O).sub.2, O-interrupted substituted or unsubstituted C1-C9-alkylene, C2-C8-alkenylene, C2-C8-alkynylene or arylene group, phenyl units or substituted phenyl units.