C07D309/32

Herbicidal propynyl-phenyl compounds

The present invention relates to a compound of formula (I) wherein: R.sup.1 is C.sub.1-C.sub.3alkoxy, C.sub.1-C.sub.2alkoxy-C.sub.1-C.sub.3alkoxy, C.sub.1-C.sub.2fluoroalkoxy, ethyl, n-propyl, n-butyl, cyclopropyl or ethynyl; R.sup.2 is hydrogen, ethyl, n-propyl, cyclopropyl, vinyl, ethynyl, C.sub.1-C.sub.3alkoxy, C.sub.1-C.sub.3fluoroalkyl, C.sub.1-C.sub.2fluoroalkoxy, C.sub.1-C.sub.2alkoxy-C.sub.1-C.sub.3alkoxy-, or C.sub.1fluoroalkoxy-C.sub.1-C.sub.3alkoxy-; provided that when R.sup.1 is ethyl, n-propyl, n-butyl, cyclopropyl or ethynyl, then R.sup.2 is hydrogen, ethyl, n-propyl, cyclopropyl, vinyl or ethynyl; and Y is O, S, S(O), S(O).sub.2, N(C.sub.1-C.sub.2alkyl), N(C.sub.1-C.sub.2alkoxy), C(O), CR.sup.8R.sup.9 or CR.sup.10R.sup.11CR.sup.12R.sup.13; and G, R.sup.3, R.sup.4, R.sup.5 and R.sup.6 are as defined herein; wherein the compound of formula (I) is optionally present as an agrochemically acceptable salt thereof. These compounds are suitable for use as herbicides. The invention therefore also relates to a method of controlling weeds, especially grassy monocotyledonous weeds, in crops of useful plants, comprising applying a compound of formula (I), or a herbicidal composition comprising such a compound, to the plants or to the locus thereof. ##STR00001##

Herbicidal propynyl-phenyl compounds

The present invention relates to a compound of formula (I) wherein: R.sup.1 is C.sub.1-C.sub.3alkoxy, C.sub.1-C.sub.2alkoxy-C.sub.1-C.sub.3alkoxy, C.sub.1-C.sub.2fluoroalkoxy, ethyl, n-propyl, n-butyl, cyclopropyl or ethynyl; R.sup.2 is hydrogen, ethyl, n-propyl, cyclopropyl, vinyl, ethynyl, C.sub.1-C.sub.3alkoxy, C.sub.1-C.sub.3fluoroalkyl, C.sub.1-C.sub.2fluoroalkoxy, C.sub.1-C.sub.2alkoxy-C.sub.1-C.sub.3alkoxy-, or C.sub.1fluoroalkoxy-C.sub.1-C.sub.3alkoxy-; provided that when R.sup.1 is ethyl, n-propyl, n-butyl, cyclopropyl or ethynyl, then R.sup.2 is hydrogen, ethyl, n-propyl, cyclopropyl, vinyl or ethynyl; and Y is O, S, S(O), S(O).sub.2, N(C.sub.1-C.sub.2alkyl), N(C.sub.1-C.sub.2alkoxy), C(O), CR.sup.8R.sup.9 or CR.sup.10R.sup.11CR.sup.12R.sup.13; and G, R.sup.3, R.sup.4, R.sup.5 and R.sup.6 are as defined herein; wherein the compound of formula (I) is optionally present as an agrochemically acceptable salt thereof. These compounds are suitable for use as herbicides. The invention therefore also relates to a method of controlling weeds, especially grassy monocotyledonous weeds, in crops of useful plants, comprising applying a compound of formula (I), or a herbicidal composition comprising such a compound, to the plants or to the locus thereof. ##STR00001##

COMPOUNDS AND METHODS OF TREATING BACTERIAL INFECTIONS

The invention relates to compounds of Formula I,

##STR00001##

wherein the variables are as defined in the claims, which are useful in the treatment and/or prevention of bacterial infections in a subject. The invention further relates to the use of a compound of Formula I in the manufacture of a medicament, and medical devices when used in a method of treating or preventing a bacterial infection in a subject, and related aspects.

COMPOUNDS AND METHODS OF TREATING BACTERIAL INFECTIONS

The invention relates to compounds of Formula I,

##STR00001##

wherein the variables are as defined in the claims, which are useful in the treatment and/or prevention of bacterial infections in a subject. The invention further relates to the use of a compound of Formula I in the manufacture of a medicament, and medical devices when used in a method of treating or preventing a bacterial infection in a subject, and related aspects.

Polycyclic glyoxylates as photoinitiators

The present invention relates to photoinitiator compounds of the formula (1) wherein X is O, S or a direct bond; Y is O, S or CR.sub.9R.sub.10; R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6, R.sub.7 and R.sub.8 independently of each other are hydrogen, halogen, C.sub.1-C.sub.18alkyl, C.sub.5-C.sub.10cycloalkyl, C.sub.2-C.sub.18alkenyl, phenyl, C.sub.1-C.sub.4alkoxy, C.sub.5-C.sub.7cycloalkoxy, phenoxy, C.sub.1-C.sub.4-alkylthio, C.sub.5-C.sub.7cycloalkylthio, phenylthio, di(C.sub.1-C.sub.4alkyl)amino, di(C.sub.5-C.sub.7cycloalkyl)amino, N-morpholinyl, N-piperidinyl or a group of formula (2) provided that one or more than one of R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6, R.sub.7 or R.sub.8 is a group of formula (2); R.sub.9, R.sub.10 independently of each other are hydrogen, C.sub.1-C.sub.18alkyl, C.sub.2-C.sub.12alkenyl, C.sub.5-C.sub.10cycloalkyl, phenyl-C.sub.1-C.sub.4alkyl, phenyl or together with the C atom to which they are attached form a 5-membered, 6-membered or 7-membered ring; and R.sub.11 is hydrogen, C.sub.1-C.sub.18alkyl, C.sub.5-C.sub.10cycloalkyl, C.sub.2-C.sub.12alkenyl, phenyl-C.sub.1-C.sub.4alkyl or phenyl. ##STR00001##

Polycyclic glyoxylates as photoinitiators

The present invention relates to photoinitiator compounds of the formula (1) wherein X is O, S or a direct bond; Y is O, S or CR.sub.9R.sub.10; R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6, R.sub.7 and R.sub.8 independently of each other are hydrogen, halogen, C.sub.1-C.sub.18alkyl, C.sub.5-C.sub.10cycloalkyl, C.sub.2-C.sub.18alkenyl, phenyl, C.sub.1-C.sub.4alkoxy, C.sub.5-C.sub.7cycloalkoxy, phenoxy, C.sub.1-C.sub.4-alkylthio, C.sub.5-C.sub.7cycloalkylthio, phenylthio, di(C.sub.1-C.sub.4alkyl)amino, di(C.sub.5-C.sub.7cycloalkyl)amino, N-morpholinyl, N-piperidinyl or a group of formula (2) provided that one or more than one of R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6, R.sub.7 or R.sub.8 is a group of formula (2); R.sub.9, R.sub.10 independently of each other are hydrogen, C.sub.1-C.sub.18alkyl, C.sub.2-C.sub.12alkenyl, C.sub.5-C.sub.10cycloalkyl, phenyl-C.sub.1-C.sub.4alkyl, phenyl or together with the C atom to which they are attached form a 5-membered, 6-membered or 7-membered ring; and R.sub.11 is hydrogen, C.sub.1-C.sub.18alkyl, C.sub.5-C.sub.10cycloalkyl, C.sub.2-C.sub.12alkenyl, phenyl-C.sub.1-C.sub.4alkyl or phenyl. ##STR00001##

Therapeutic compounds and methods of use thereof
10584108 · 2020-03-10 · ·

The invention provides compounds that are useful for treating or preventing cancer.

Therapeutic compounds and methods of use thereof
10584108 · 2020-03-10 · ·

The invention provides compounds that are useful for treating or preventing cancer.

CYCLIZATION PROCESSES OF HYDROXYALKENOIC AICDS AND PRODUCTS THEREOF

The invention provides efficient cyclization processes of hydroxyalkenoic acids and products produced therefrom. The following reactions are claimed: Formula (I), (II), (V) and (VI).

##STR00001##

CYCLIZATION PROCESSES OF HYDROXYALKENOIC AICDS AND PRODUCTS THEREOF

The invention provides efficient cyclization processes of hydroxyalkenoic acids and products produced therefrom. The following reactions are claimed: Formula (I), (II), (V) and (VI).

##STR00001##