Patent classifications
C07D333/50
COMPOUNDS FOR THE TREATMENT OF PARAMYXOVIRUS VIRAL INFECTIONS
Disclosed herein are new antiviral compounds, together with pharmaceutical compositions that include one or more antiviral compounds, and methods of synthesizing the same. Also disclosed herein are methods of ameliorating and/or treating a paramyxovirus viral infection with one or more small molecule compounds. Examples of paramyxovirus infection include an infection caused by human respiratory syncytial virus (RSV).
COMPOUNDS FOR THE TREATMENT OF PARAMYXOVIRUS VIRAL INFECTIONS
Disclosed herein are new antiviral compounds, together with pharmaceutical compositions that include one or more antiviral compounds, and methods of synthesizing the same. Also disclosed herein are methods of ameliorating and/or treating a paramyxovirus viral infection with one or more small molecule compounds. Examples of paramyxovirus infection include an infection caused by human respiratory syncytial virus (RSV).
Monoamine compound and organic electroluminescence device including the same
Provided are a monoamine compound and an organic electroluminescence device including the same. The monoamine compound according to an example embodiment is represented by the following Formula 1 ##STR00001##
Monoamine compound and organic electroluminescence device including the same
Provided are a monoamine compound and an organic electroluminescence device including the same. The monoamine compound according to an example embodiment is represented by the following Formula 1 ##STR00001##
COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE
A compound for an organic optoelectronic device, a composition for an organic optoelectronic device, an organic optoelectronic device, and a display device, the compound being represented by Chemical Formula 1:
##STR00001##
COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE
A compound for an organic optoelectronic device, a composition for an organic optoelectronic device, an organic optoelectronic device, and a display device, the compound being represented by Chemical Formula 1:
##STR00001##
Thiophene derivatives for the treatment of disorders caused by IgE
- Pfrafulkumar Tulshibhai Chovatia ,
- Rickki Lee Connelly ,
- Richard Jeremy Franklin ,
- Gregory William Haslett ,
- Alistair James Henry ,
- James Madden ,
- Judi Charlotte Neuss ,
- Timothy John Norman ,
- Oliver Philps ,
- William Ross Pitt ,
- Konstantinos Rampalakos ,
- Matthew Duncan Selby ,
- Suganthan Selvaratnam ,
- Giancarlo Trani ,
- Zhaoning Zhu
Thiophene derivatives of formula (I) and a pharmaceutically acceptable salt thereof are provided. These compounds have utility for the treatment or prevention of disorders caused by IgE, such as allergy, type 1 hypersensitivity or familiar sinus inflammation.
##STR00001##
Thiophene derivatives for the treatment of disorders caused by IgE
- Pfrafulkumar Tulshibhai Chovatia ,
- Rickki Lee Connelly ,
- Richard Jeremy Franklin ,
- Gregory William Haslett ,
- Alistair James Henry ,
- James Madden ,
- Judi Charlotte Neuss ,
- Timothy John Norman ,
- Oliver Philps ,
- William Ross Pitt ,
- Konstantinos Rampalakos ,
- Matthew Duncan Selby ,
- Suganthan Selvaratnam ,
- Giancarlo Trani ,
- Zhaoning Zhu
Thiophene derivatives of formula (I) and a pharmaceutically acceptable salt thereof are provided. These compounds have utility for the treatment or prevention of disorders caused by IgE, such as allergy, type 1 hypersensitivity or familiar sinus inflammation.
##STR00001##
NIR TO SWIR FLUORESCENT COMPOUNDS FOR IMAGING AND DETECTION
This disclosure provides a family of compounds that absorb and fluoresce in the short wave infrared region (SWIR, optionally 1000 nm to 1300 nm), including hydrophilic compounds that exhibit absorption and emission spectral profiles in aqueous solutions substantially similar to those observed in organic solvents such as methanol or DMSO. The compounds can be chemically linked to biomolecules including proteins, nucleic acids, and therapeutic small molecules. The compounds are useful for imaging in a variety of medical, biological and diagnostic applications, including SWIR in vivo imaging of regions of interest within a mammal.
NIR TO SWIR FLUORESCENT COMPOUNDS FOR IMAGING AND DETECTION
This disclosure provides a family of compounds that absorb and fluoresce in the short wave infrared region (SWIR, optionally 1000 nm to 1300 nm), including hydrophilic compounds that exhibit absorption and emission spectral profiles in aqueous solutions substantially similar to those observed in organic solvents such as methanol or DMSO. The compounds can be chemically linked to biomolecules including proteins, nucleic acids, and therapeutic small molecules. The compounds are useful for imaging in a variety of medical, biological and diagnostic applications, including SWIR in vivo imaging of regions of interest within a mammal.