C07D419/14

ETHER LINKED TRIAZOLES AS NRF2 ACTIVATORS

The present invention relates to ether-linked triazole compounds, methods of making them, pharmaceutical compositions containing them and their use as NRF2 activators. In particular, the invention relates to compounds of Formula (I), and pharmaceutically acceptable salts thereof:

##STR00001##

ETHER LINKED TRIAZOLES AS NRF2 ACTIVATORS

The present invention relates to ether-linked triazole compounds, methods of making them, pharmaceutical compositions containing them and their use as NRF2 activators. In particular, the invention relates to compounds of Formula (I), and pharmaceutically acceptable salts thereof:

##STR00001##

INHIBITORS OF KEAP1-Nrf2 PROTEIN-PROTEIN INTERACTION

Sultam compounds, pharmaceutical compositions containing them, methods of making them, and methods of using them including methods for treating disease states, disorders, and conditions associated with the KEAP1-Nrf2 interaction, such as inflammatory bowel disease, including Crohn's disease and ulcerative colitis.

Compositions and methods for inhibition of the JAK pathway

Disclosed are compounds of formula I, compositions containing them, and methods of use for the compounds and compositions in the treatment of conditions in which modulation of the JAK pathway or inhibition of JAK kinases, particularly JAK 2 and JAK3, are therapeutically useful.

Compositions and methods for inhibition of the JAK pathway

Disclosed are compounds of formula I, compositions containing them, and methods of use for the compounds and compositions in the treatment of conditions in which modulation of the JAK pathway or inhibition of JAK kinases, particularly JAK 2 and JAK3, are therapeutically useful.

MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES

The present invention relates to compounds which are suitable for use in electronic devices, and to electronic devices, in particular organic electroluminescent devices, containing these compounds.

MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES

The present invention relates to compounds which are suitable for use in electronic devices, and to electronic devices, in particular organic electroluminescent devices, containing these compounds.

Compound for organic electric element, organic electric element using the same, and electronic device thereof

Provided is a novel compound capable of improving the luminous efficiency, stability and life span of a device, an organic electric element using the same, and an electronic device thereof.

NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME
20240109884 · 2024-04-04 ·

Provided is a compound of Chemical Formula 1:

##STR00001## wherein: A.sub.1 represents Chemical Formula 1-a:

##STR00002## where X is O or S; and Ar.sub.1 is a substituted or unsubstituted C.sub.6-60 aryl or C.sub.2-60 heteroaryl containing at least one of N, O and S; and A.sub.2 is Chemical Formula 1-b or Chemical Formula 1-c:

##STR00003##

wherein: L.sub.1 to L.sub.4 are each independently a single bond, a substituted or unsubstituted C.sub.6-60 arylene, or a substituted or unsubstituted C.sub.2-60 heteroarylene containing at least one of N, O and S; Ar.sub.2 to Ar.sub.5 are each independently a substituted or unsubstituted C.sub.6-60 aryl or C.sub.2-60 heteroaryl containing at least one of N, O and S; D is deuterium; and n is an integer of 0 to 5, and an organic light emitting device including the same. An organic light-emitting device containing the compound exhibits improved efficiency, driving voltage and/or lifespan characteristics.

NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME
20240109884 · 2024-04-04 ·

Provided is a compound of Chemical Formula 1:

##STR00001## wherein: A.sub.1 represents Chemical Formula 1-a:

##STR00002## where X is O or S; and Ar.sub.1 is a substituted or unsubstituted C.sub.6-60 aryl or C.sub.2-60 heteroaryl containing at least one of N, O and S; and A.sub.2 is Chemical Formula 1-b or Chemical Formula 1-c:

##STR00003##

wherein: L.sub.1 to L.sub.4 are each independently a single bond, a substituted or unsubstituted C.sub.6-60 arylene, or a substituted or unsubstituted C.sub.2-60 heteroarylene containing at least one of N, O and S; Ar.sub.2 to Ar.sub.5 are each independently a substituted or unsubstituted C.sub.6-60 aryl or C.sub.2-60 heteroaryl containing at least one of N, O and S; D is deuterium; and n is an integer of 0 to 5, and an organic light emitting device including the same. An organic light-emitting device containing the compound exhibits improved efficiency, driving voltage and/or lifespan characteristics.