The present invention relates to compounds of formula (I): wherein Q is selected from O or S; R.sup.1 and R.sup.3 are each independently hydrogen or an optionally substituted hydrocarbyl group, or R.sup.1 and R.sup.3 together with the nitrogen atom to which they are attached may form a 3- to 12-membered optionally substituted cyclic group; and R.sup.2 is a cyclic group substituted at the position, wherein R.sup.2 may optionally be further substituted. The present invention further relates to salts, solvates and prodrugs of such compounds, to pharmaceutical compositions comprising such compounds, and to the use of such compounds in the treatment and prevention of medical disorders and diseases, most especially by the inhibition of NLRP3.

##STR00001##

Provided herein are, inter alia, methods of treating cancer using compounds of the invention.

Provided herein are, inter alia, methods of treating cancer using compounds of the invention.

Reversibly cross-linkable foam is provided. The reversibly cross-linked foam includes a first polymeric material, at least one reversibly cross-linkable monomer polymerized with the first polymeric material, and at least one blowing agent. The reversibly cross-linkable co-polymeric foam is thermally stable at temperatures of at least 10 degrees higher than otherwise identical polymeric foam that does not include the reversibly cross-linkable agent polymerized with the first polymeric material.

Compounds of formula I
A-B  (I), wherein A is a radical selected from the group consisting of formulae A.sub.1 to A.sub.8: ##STR00001## wherein the arrow denotes the point of attachment to the radical B; and B is a radical selected from the group consisting of formulae B.sub.1 to B.sub.11: ##STR00002## wherein the arrow denotes the point of attachment to the radical A; and wherein the substituents are as defined in claim 1, and the agrochemically acceptable salts and all stereoisomers and tautomeric forms of the compounds of formula I can be used as insecticides and can be prepared in a manner known per se.

Compounds of formula I
A-B  (I), wherein A is a radical selected from the group consisting of formulae A.sub.1 to A.sub.8: ##STR00001## wherein the arrow denotes the point of attachment to the radical B; and B is a radical selected from the group consisting of formulae B.sub.1 to B.sub.11: ##STR00002## wherein the arrow denotes the point of attachment to the radical A; and wherein the substituents are as defined in claim 1, and the agrochemically acceptable salts and all stereoisomers and tautomeric forms of the compounds of formula I can be used as insecticides and can be prepared in a manner known per se.

This disclosure relates to methods of treatment using compound (1) or analogs thereof, and pharmaceutically acceptable salts thereof. Also disclosed are compounds of formula (10):

##STR00001##

as defined in the specification, and pharmaceutically acceptable salts thereof, as well as pharmaceutical compositions comprising the same. Methods of treatment, such as for cancer, are provided that comprise administering the compounds and their salts to a subject in need of such treatment.

This disclosure relates to methods of treatment using compound (1) or analogs thereof, and pharmaceutically acceptable salts thereof. Also disclosed are compounds of formula (10):

##STR00001##

as defined in the specification, and pharmaceutically acceptable salts thereof, as well as pharmaceutical compositions comprising the same. Methods of treatment, such as for cancer, are provided that comprise administering the compounds and their salts to a subject in need of such treatment.

Compounds of formula I

A-B  (I),

wherein A is a radical selected from the group consisting of formulae A.sub.1 to A.sub.8:

##STR00001##

wherein the arrow denotes the point of attachment to the radical B; and
B is a radical selected from the group consisting of formulae B.sub.1 to B.sub.11:

##STR00002## ##STR00003##

wherein the arrow denotes the point of attachment to the radical A; and wherein the substituents are as defined in claim 1, and the agrochemically acceptable salts and all stereoisomers and tautomeric forms of the compounds of formula I can be used as insecticides and can be prepared in a manner known per se.

Compounds of formula I

A-B  (I),

wherein A is a radical selected from the group consisting of formulae A.sub.1 to A.sub.8:

##STR00001##

wherein the arrow denotes the point of attachment to the radical B; and
B is a radical selected from the group consisting of formulae B.sub.1 to B.sub.11:

##STR00002## ##STR00003##

wherein the arrow denotes the point of attachment to the radical A; and wherein the substituents are as defined in claim 1, and the agrochemically acceptable salts and all stereoisomers and tautomeric forms of the compounds of formula I can be used as insecticides and can be prepared in a manner known per se.