The present disclosure relates to novel compounds and pharmaceutical compositions thereof, and methods for inhibiting the activity of FGFR enzymes with the compounds and compositions of the disclosure. The present disclosure further relates to, but is not limited to, methods for treating disorders associated with FGFR signaling with the compounds and compositions of the disclosure.

The present disclosure relates to novel compounds and pharmaceutical compositions thereof, and methods for inhibiting the activity of FGFR enzymes with the compounds and compositions of the disclosure. The present disclosure further relates to, but is not limited to, methods for treating disorders associated with FGFR signaling with the compounds and compositions of the disclosure.

An object of the present invention is to provide an electrode material for an organic semiconductor device which maintains excellent conductivity and of which contact properties with an organic semiconductor becomes favorable. The electrode material for an organic semiconductor device of the present invention contains inorganic nanoparticles and an organic π-conjugated ligand, in which the organic π-conjugated ligand is a ligand having at least one electron-withdrawing substituent.

A low-molecular-weight fused polycyclic heteroaromatic compound has a compact planar structure in which seven or more aromatic rings and heteroaromatic rings are fused together, and thereby exhibits relatively high charge mobility, and improved processibility due to improved dissolubility for a solvent. An organic thin film and an electronic device include the fused polycyclic heteroaromatic compound expressed in Chemical Formula 1.

A low-molecular-weight fused polycyclic heteroaromatic compound has a compact planar structure in which seven or more aromatic rings and heteroaromatic rings are fused together, and thereby exhibits relatively high charge mobility, and improved processibility due to improved dissolubility for a solvent. An organic thin film and an electronic device include the fused polycyclic heteroaromatic compound expressed in Chemical Formula 1.

Provided are macrocyclic compounds comprising at least one eight-membered ring and at least four further 5-membered or 6-membered carbocyclic and heterocyclic rings which may be further substituted. Also provided are formulations comprising these macrocyclic compounds. Further provided are organic light emitting devices (OLEDs) and related consumer products that utilize these macrocyclic compounds.

Provided are macrocyclic compounds comprising at least one eight-membered ring and at least four further 5-membered or 6-membered carbocyclic and heterocyclic rings which may be further substituted. Also provided are formulations comprising these macrocyclic compounds. Further provided are organic light emitting devices (OLEDs) and related consumer products that utilize these macrocyclic compounds.

Compounds, systems, and methods are provided for the design and assembly of a non-invasive, analyte sensing dressing. The dressing can be therapeutic. The dressing includes a sensor and a matrix. The sensor is capable of detecting analytes such as molecular oxygen, carbon dioxide, nitric oxides, dissolved analytes in plasma, and hydrogen ions. The matrix is at least partially permeable to the analyte. The device emits a detectable signal when the sensor is excited in the presence of the analyte. In one version of the dressing, the sensor includes a meso-unsubstituted metallated porphyrin that is sensitive towards oxygen. The metallated porphyrin can be excited when illuminated at a first wavelength, followed by emission of phosphorescence at a second wavelength whose intensity can be used as an indicator for oxygen concentration.

Compounds, systems, and methods are provided for the design and assembly of a non-invasive, analyte sensing dressing. The dressing can be therapeutic. The dressing includes a sensor and a matrix. The sensor is capable of detecting analytes such as molecular oxygen, carbon dioxide, nitric oxides, dissolved analytes in plasma, and hydrogen ions. The matrix is at least partially permeable to the analyte. The device emits a detectable signal when the sensor is excited in the presence of the analyte. In one version of the dressing, the sensor includes a meso-unsubstituted metallated porphyrin that is sensitive towards oxygen. The metallated porphyrin can be excited when illuminated at a first wavelength, followed by emission of phosphorescence at a second wavelength whose intensity can be used as an indicator for oxygen concentration.

The purpose of the present invention is to provide: composite phthalocyanine microparticles of a nano-order level, preferably on the order of 100 nm, that are optimal as a coloring material; and a method for producing the same. Provided is a method for producing composite phthalocyanine microparticles, the method being characterized by including a step (1) for preparing a dissolved solution by dissolving at least copper phthalocyanine and titanyl phthalocyanine and/or cobalt phthalocyanine as raw materials in a first solvent, a step (2) for precipitating composite phthalocyanine by mixing the dissolved solution obtained in step (1) with a second solvent that serves as a poor solvent of the abovementioned raw materials, and a step (3) for causing an organic solvent to act on the composite phthalocyanine obtained in step (2). Also provided are composite phthalocyanine microparticles containing at least copper phthalocyanine and titanyl phthalocyanine and/or cobalt phthalocyanine, the composite phthalocyanine microparticles having an aspect ratio of 1.1-2.5 and a particle size of 5-100 nm.