A mutant strain of a filamentous fungus of the genus Trichoderma having a reduced function of a polypeptide consisting of the amino acid sequence represented by SEQ ID NO: 2; and a method of producing a sugar from a cellulose-containing biomass, the method including: step a of producing a cellulase by cultivating a Trichoderma reesei mutant strain having a reduced function of a polypeptide consisting of the amino acid sequence represented by SEQ ID NO: 2, and step b of saccharifying the biomass by using the cellulase obtained in the step a.

A method of expressing hydrophobin in a soluble form and a method of purifying hydrophobin, and more particularly, to a method of expressing a recombinant fusion protein including hydrophobin in a soluble form in a host cell and then purifying the expressed recombinant fusion protein are provided.

A method of expressing hydrophobin in a soluble form and a method of purifying hydrophobin, and more particularly, to a method of expressing a recombinant fusion protein including hydrophobin in a soluble form in a host cell and then purifying the expressed recombinant fusion protein are provided.

Disclosed are carbohydrate binding module variants, as well as variants of a glycoside hydrolase comprising the carbohydrate binding module variants. The variants having glycoside hydrolase activity comprising the carbohydrate binding module variants have improved stability in the presence of a protease, and are useful in detergent applications, such as laundry or dish wash.

Disclosed are carbohydrate binding module variants, as well as variants of a glycoside hydrolase comprising the carbohydrate binding module variants. The variants having glycoside hydrolase activity comprising the carbohydrate binding module variants have improved stability in the presence of a protease, and are useful in detergent applications, such as laundry or dish wash.

The present invention generally relates to methods of producing one or more indole diterpene compounds in the epoxy janthitrem biosynthetic pathway and polynucleotides, polypeptides, expression constructs and host cells useful in the production of one or more indole diterpene compounds, and methods of using same to confer a benefit to an organism, such as increased insect pest resistance.

The present invention generally relates to methods of producing one or more indole diterpene compounds in the epoxy janthitrem biosynthetic pathway and polynucleotides, polypeptides, expression constructs and host cells useful in the production of one or more indole diterpene compounds, and methods of using same to confer a benefit to an organism, such as increased insect pest resistance.

An edible mass comprising fungal particles of a filamentous fungus which can more readily be used in production of sweet products and/or has reduced mushroom taste whilst maintaining desired nutritional attributes is described. The mass may include relatively low levels of acetyl-glutamic acid, uridine, inosine, guanosine, UMP, GMP, AMP, sodium, potassium and/or ammonium.

Polypeptides which may be used for preventing or treating allergy to moulds of the Cladosporium and/or Alternaria genus, have up to 30 amino acids in length and comprise: (I) the amino acid sequence: (a) GGYKAAVRPTMLE (SEQ ID NO: 35; Cla35), (b) AE V YQKLK SLTKK (SEQ ID NO: 31; Cla16), (c) VAITYASRAQGAE (SEQ ID NO: 32; Cla25), (d) GHHFKERGT-GSLVIT (SEQ ID NO: 33; Cla26), or (e) ANYTQTKTVSIRL (SEQ ID NO: 34; Cla29); or (II) a T cell epitope-containing variant sequence which is a said amino acid sequence (I) having up to six amino acid modifications, each of which is independently a deletion, substitution or insertion.

Polypeptides which may be used for preventing or treating allergy to moulds of the Cladosporium and/or Alternaria genus, have up to 30 amino acids in length and comprise: (I) the amino acid sequence: (a) GGYKAAVRPTMLE (SEQ ID NO: 35; Cla35), (b) AE V YQKLK SLTKK (SEQ ID NO: 31; Cla16), (c) VAITYASRAQGAE (SEQ ID NO: 32; Cla25), (d) GHHFKERGT-GSLVIT (SEQ ID NO: 33; Cla26), or (e) ANYTQTKTVSIRL (SEQ ID NO: 34; Cla29); or (II) a T cell epitope-containing variant sequence which is a said amino acid sequence (I) having up to six amino acid modifications, each of which is independently a deletion, substitution or insertion.