Provided are a hydroxyalkylalkyl cellulose excellent in formability and not causing marked delay in disintegration when added even in a small amount; a solid preparation including the hydroxyalkylalkyl cellulose; and a method for producing the solid preparation. More specifically, provided are a hydroxyalkylalkyl cellulose for tableting having a specific surface area of from 0.5 to 5.0 m.sup.2/g as measured by BET and a solid preparation including the hydroxyalkylalkyl cellulose. Also provided is a method for producing the hydroxyalkylalkyl cellulose for tableting, including the steps of: bringing pulp into contact with an alkali metal hydroxide solution to obtain an alkali cellulose, reacting the alkali cellulose with an etherifying agent to obtain a first hydroxyalkylalkyl cellulose, grinding the first hydroxyalkylalkyl cellulose, and subjecting the ground first hydroxyalkylalkyl cellulose to hydrolysis in the presence of an acid catalyst or oxidative degradation in the presence of an oxidant to obtain a second hydroxyalkylalkyl cellulose.

In various aspects, the invention provides compositions of variable-length hydrophobically-modified polymers. These variable-length hydrophobes decorated along the hydrophilic polymer backbone provide advanced properties and allow for precise control over the behavior of the resulting amphiphilic polymer, including in aqueous solution. Such control allows for enhanced functionality of the amphiphilic polymer relative to standard single-length hydrophobe grafting designs, including for hemostasis.

There is provided a method for producing a hydroxyalkyl alkyl cellulose having a high storage modulus (thermal gel strength) and a small number of undissolved fibers. More specifically, there is provided a method for producing a hydroxyalkyl alkyl cellulose including steps of: bringing sheet-shaped pulp having a pore volume of 0.55 ml/g or more and less than 1.00 ml/g or chip-shaped pulp obtained by cutting the sheet-shaped pulp into contact with a first alkali metal hydroxide solution to obtain an alkali cellulose mixture, removing a liquid from the alkali cellulose mixture to obtain alkali cellulose, reacting the alkali cellulose with an alkylating agent and a hydroxyalkylating agent to obtain a first reaction mixture, mixing the first reaction mixture with a second alkali metal hydroxide solution to obtain a second reaction mixture, and purifying the second reaction mixture to obtain a hydroxyalkyl alkyl cellulose.

Cellulose derivative particles including an alkoxy group having 2 or more carbons or an acyl group having 3 or more carbons, wherein the cellulose derivative particles have an average particle size of 80 nm or greater and 100 μm or less, a sphericity of 70% or greater and 100% or less, and a surface smoothness of 80% or greater and 100% or less; and a total substitution degree of the cellulose derivative is 0.7 or greater and 3 or less.

In various aspects, the invention provides compositions of variable-length hydrophobically-modified polymers. These variable-length hydrophobes decorated along the hydrophilic polymer backbone provide advanced properties and allow for precise control over the behavior of the resulting amphiphilic polymer, including in aqueous solution. Such control allows for enhanced functionality of the amphiphilic polymer relative to standard single-length hydrophobe grafting designs, including for hemostasis.

Disclosed herein is a polymer composition comprising an effective amount of a hydrophobically-modified polymer having functional groups along the backbone occupied by a fatty anhydride moiety. The polymer composition has a potent hemostatic action by gelling blood upon contact, and is suitable for treating internal and external bleeds. As disclosed herein, the modified polymer can be generated without the use of toxic reagents that would require removal from the product. Further, compositions are shelf stable even in a flowable form. That is, the hydrophobic grafts are not lost under product storage conditions (e.g., room temperature storage).

The present invention relates to a polysaccharide derivative which is able to not only enhance cleaning properties of clothing, etc. but also suppress resoiling due to powder soil during washing. The polysaccharide derivative is a polysaccharide derivative having a cationic group and a hydrocarbon group (R) having 2 or more carbon atoms, wherein the hydrocarbon group (R) is bound to a group resulting from eliminating a hydrogen atom from a hydroxy group of a hydroxyalkylated polysaccharide, directly or via a hydrocarbon group having an oxygen atom; the hydroxyalkylated polysaccharide is a hydroxyethylated polysaccharide or a hydroxypropylated polysaccharide; and the hydroxyalkylated polysaccharide has a weight average molecular weight of 10,000 or more and 740,000 or less.

The present invention relates to a polysaccharide derivative which is able to not only enhance cleaning properties of clothing, etc. but also suppress resoiling due to powder soil during washing. The polysaccharide derivative is a polysaccharide derivative having a cationic group and a hydrocarbon group (R) having 2 or more carbon atoms, wherein the hydrocarbon group (R) is bound to a group resulting from eliminating a hydrogen atom from a hydroxy group of a hydroxyalkylated polysaccharide, directly or via a hydrocarbon group having an oxygen atom; the hydroxyalkylated polysaccharide is a hydroxyethylated polysaccharide or a hydroxypropylated polysaccharide; and the hydroxyalkylated polysaccharide has a weight average molecular weight of 10,000 or more and 740,000 or less.

The present invention is a method for producing a modified cellulose including the following step A: step A: introducing a cellulose raw material with a substituent having 6 or more carbon atoms to a group in which a hydrogen atom is removed from a hydroxyl group of a cellulose backbone, in the presence of water and a surfactant. The present invention relates to a method for producing a modified cellulose having a high affinity of an organic solvent, a resin or the like, and a hydrophobic medium, using a reaction system with low environmental loads and with prospects of reduction in production costs.

The present invention is a method for producing a modified cellulose including the following step A: step A: introducing a cellulose raw material with a substituent having 6 or more carbon atoms to a group in which a hydrogen atom is removed from a hydroxyl group of a cellulose backbone, in the presence of water and a surfactant. The present invention relates to a method for producing a modified cellulose having a high affinity of an organic solvent, a resin or the like, and a hydrophobic medium, using a reaction system with low environmental loads and with prospects of reduction in production costs.