The present invention provides a composition comprising 1) an aqueous dispersion of polymer particles having a core-shell morphology wherein the core protuberates from the shell; wherein the core comprises from 5 to 90 weight percent structural units of a fluoroalkylated monomer, and 2) less than 0.09 weight percent structural units of a phosphorus acid monomer; and wherein the shell comprises from 0.1 to 5 weight percent of itaconic acid or a phosphorus acid monomer, based on the weight of the shell. The present invention addresses a need in the art by providing a way of selectively concentrating fluoroalkyl functionality into polymer particles with acorn morphology, thereby providing an improvement in dirt pick-up resistance of the subsequent coating.

The present invention provides a sensitizer for nucleic acid amplification which is a polymer containing a constitutional unit derived from a monomer represented by the following formula (1):

##STR00001##

wherein symbols are as defined in the specification.

The present invention provides a sensitizer for nucleic acid amplification which is a polymer containing a constitutional unit derived from a monomer represented by the following formula (1):

##STR00001##

wherein symbols are as defined in the specification.

The invention is related to a cost-effective method for making a coated contact lens having a hydrogel coating thereon. A method of the invention involves heating a contact lens precursor having carboxylic acid groups on and/or near its surface in an aqueous solution in the presence of a hydrophilic copolymer that comprises monomeric units of (a) at least one epoxy-containing vinylic monomer, (b) at least one amino-containing vinylic monomer having a primary or secondary amino group, (c) at least one polyethyleneglycol-containing vinylic monomer, and (d) at least one phosphorylcholine-containing vinylic monomer, at a temperature from about 100? C. to about 140? C. for at least 30 minutes, thereby forming a hydrogel coating on the contact lens precursor. Such a method can be advantageously implemented directly in a sealed lens package during autoclave.

The invention is related to a cost-effective method for making a coated contact lens having a hydrogel coating thereon. A method of the invention involves heating a contact lens precursor having carboxylic acid groups on and/or near its surface in an aqueous solution in the presence of a hydrophilic copolymer that comprises monomeric units of (a) at least one epoxy-containing vinylic monomer, (b) at least one amino-containing vinylic monomer having a primary or secondary amino group, (c) at least one polyethyleneglycol-containing vinylic monomer, and (d) at least one phosphorylcholine-containing vinylic monomer, at a temperature from about 100? C. to about 140? C. for at least 30 minutes, thereby forming a hydrogel coating on the contact lens precursor. Such a method can be advantageously implemented directly in a sealed lens package during autoclave.

A method of producing a monomer composition including a polymerizable group-containing phosphoric acid compound is provided. The method includes a step of allowing a polymerizable group-containing alcohol compound, which is a compound not containing a urethane bond, to react with phosphorus pentoxide in the presence of a urethane compound, thereby obtaining a monomer composition including a polymerizable group-containing phosphoric acid compound.

A method of producing a monomer composition including a polymerizable group-containing phosphoric acid compound is provided. The method includes a step of allowing a polymerizable group-containing alcohol compound, which is a compound not containing a urethane bond, to react with phosphorus pentoxide in the presence of a urethane compound, thereby obtaining a monomer composition including a polymerizable group-containing phosphoric acid compound.

There is provided hollow resin particles used in a resin composition for semiconductor members, which can be used in a resin composition for semiconductor members to provide a semiconductor member capable of exerting excellent low dielectric properties. The hollow resin particles used in a resin composition for semiconductor members according to an embodiment of the present invention are hollow resin particles having a hole part inside the particle, wherein a decreasing rate of a relative dielectric constant Dk1 of a film (F1) formulated with 80 parts by weight of polyimide and 20 parts by weight of the hollow resin particles to a relative dielectric constant Dk0 of a film (F0) formed with only the polyimide is 3% or more.

There is provided hollow resin particles used in a resin composition for semiconductor members, which can be used in a resin composition for semiconductor members to provide a semiconductor member capable of exerting excellent low dielectric properties. The hollow resin particles used in a resin composition for semiconductor members according to an embodiment of the present invention are hollow resin particles having a hole part inside the particle, wherein a decreasing rate of a relative dielectric constant Dk1 of a film (F1) formulated with 80 parts by weight of polyimide and 20 parts by weight of the hollow resin particles to a relative dielectric constant Dk0 of a film (F0) formed with only the polyimide is 3% or more.

An object is to provide a method of manufacturing a vessel for embryoid body formation excellent in formability of an embryoid body and suitable for optical observation.