The present invention addresses the problem of providing, for example, a novel metal surface treatment agent which can form a film capable of maintaining antimicrobial performance on or over a surface of a metal material. The problem can be solved by a metal surface treatment agent containing: a prescribed copolymer (A) obtained by polymerizing a compound (a) represented by the following Formula (1) [in Formula (1), R.sup.1 and R.sup.2 each independently represent a hydrogen atom or an alkyl group having 1 to 4 carbon atoms, R.sup.3 and R.sup.4 each independently represent an alkyl group having 1 to 5 carbon atoms, and X— represents an ion of a halogen atom, or an acid anion] with a compound (b) represented by the following Formula (2) or (3) [in Formula (2), R.sup.5 represents a hydrogen atom or a methyl group, R.sup.6 and R.sup.7 each independently represent a hydrogen atom, an alkyl group having 1 to 4 carbon atoms, a benzyl group, or a hydroxyalkyl group having 2 or 3 carbon atoms; and, in Formula (3), R.sup.8 represents a hydrogen atom or a methyl group]; and a water-soluble or water-dispersible resin (B).

##STR00001##

The present invention addresses the problem of providing, for example, a novel metal surface treatment agent which can form a film capable of maintaining antimicrobial performance on or over a surface of a metal material. The problem can be solved by a metal surface treatment agent containing: a prescribed copolymer (A) obtained by polymerizing a compound (a) represented by the following Formula (1) [in Formula (1), R.sup.1 and R.sup.2 each independently represent a hydrogen atom or an alkyl group having 1 to 4 carbon atoms, R.sup.3 and R.sup.4 each independently represent an alkyl group having 1 to 5 carbon atoms, and X— represents an ion of a halogen atom, or an acid anion] with a compound (b) represented by the following Formula (2) or (3) [in Formula (2), R.sup.5 represents a hydrogen atom or a methyl group, R.sup.6 and R.sup.7 each independently represent a hydrogen atom, an alkyl group having 1 to 4 carbon atoms, a benzyl group, or a hydroxyalkyl group having 2 or 3 carbon atoms; and, in Formula (3), R.sup.8 represents a hydrogen atom or a methyl group]; and a water-soluble or water-dispersible resin (B).

##STR00001##

Polyamines are water-soluble polyelectrolytes with the amino groups that can be used to attach the polymers onto functional surfaces of fibrous materials. In addition, polyamines can be readily modified by (super)nucleophilic groups such as (alkyl)aminopyridines that enhance the polymer's ability to promote hydrolysis of organophosphorous chemical warfare agents. Furthermore, attachment of hydantoin moieties augments the number of the imide, amide, or amine groups on the polyamine's chain, which provides oxidizing properties to the resulting modified polyamine after halogenation. In one aspect, disclosed herein are polyamines with side chains modified to contain both (4-aminopyridine, APy) and 5-(4-hydroxybenzylidene)hydantoin (HBH) functionalities with enhanced content of the active bromine. Viricidal activity of the APy- and HBH-modified polyallylamine against human coronavirus (type 229E) was tested both in solution and on nylon-cotton fabric. The polymers are effective at inactivating the coronavirus, at both low concentrations and short exposure times.

Polyamines are water-soluble polyelectrolytes with the amino groups that can be used to attach the polymers onto functional surfaces of fibrous materials. In addition, polyamines can be readily modified by (super)nucleophilic groups such as (alkyl)aminopyridines that enhance the polymer's ability to promote hydrolysis of organophosphorous chemical warfare agents. Furthermore, attachment of hydantoin moieties augments the number of the imide, amide, or amine groups on the polyamine's chain, which provides oxidizing properties to the resulting modified polyamine after halogenation. In one aspect, disclosed herein are polyamines with side chains modified to contain both (4-aminopyridine, APy) and 5-(4-hydroxybenzylidene)hydantoin (HBH) functionalities with enhanced content of the active bromine. Viricidal activity of the APy- and HBH-modified polyallylamine against human coronavirus (type 229E) was tested both in solution and on nylon-cotton fabric. The polymers are effective at inactivating the coronavirus, at both low concentrations and short exposure times.

The disclosure relates to cationic polymers functionalized with substituted phenylboronic acid groups and to methods of using the same to treat metabolic and gastrointestinal disorders.

The disclosure relates to cationic polymers functionalized with substituted phenylboronic acid groups and to methods of using the same to treat metabolic and gastrointestinal disorders.

The disclosure relates to cationic polymers functionalized with substituted phenylboronic acid groups and to methods of using the same to treat metabolic and gastrointestinal disorders.

The disclosure relates to cationic polymers functionalized with substituted phenylboronic acid groups and to methods of using the same to treat metabolic and gastrointestinal disorders.

Antimicrobial/antiviral coatings are applied to substrates such as fabrics by applying and then curing a coating composition. The coating composition includes at least one free radical-curable monomer, at least one free radical initiator, and either or both of certain phenolic and/or menthol compounds and certain non-free radical-curable ammonium compounds.

Antimicrobial/antiviral coatings are applied to substrates such as fabrics by applying and then curing a coating composition. The coating composition includes at least one free radical-curable monomer, at least one free radical initiator, and either or both of certain phenolic and/or menthol compounds and certain non-free radical-curable ammonium compounds.