The present invention relates to a styrene-based resin having a weight average molecular weight Mw′ as determined by the GPC-MALS method of 1,000,000 or more and 5,000,000 or less, a degree of long-chain branching of 0.2 or more per 1,000 styrene units, and a tetrahydrofuran-insoluble matter of 0.1% by weight or less (including 0), the styrene-based resin being free from a component derived from a polyfunctional monomer in a molecular chain thereof. In a method for producing this styrene-based resin, in an impregnation step of adding a polymerization initiator and a styrene monomer in an aqueous medium, thereby impregnating the polymerization initiator and the styrene monomer in the seed particle at a temperature at which polymerization of the styrene monomer does not substantially proceed, the amount of the styrene monomer is 20 to 200 parts by weight based on 100 parts by weight of the seed particle; and in an additional impregnation polymerization step of graft polymerizing the styrene monomer on the styrene-based resin, the addition amount of the styrene monomer is 50 to 700 parts by weight based on 100 parts by weight of the seed particle, and the content of the styrene monomer in the seed particle is held at 10% by weight or less.

The present invention relates to a styrene-based resin having a weight average molecular weight Mw′ as determined by the GPC-MALS method of 1,000,000 or more and 5,000,000 or less, a degree of long-chain branching of 0.2 or more per 1,000 styrene units, and a tetrahydrofuran-insoluble matter of 0.1% by weight or less (including 0), the styrene-based resin being free from a component derived from a polyfunctional monomer in a molecular chain thereof. In a method for producing this styrene-based resin, in an impregnation step of adding a polymerization initiator and a styrene monomer in an aqueous medium, thereby impregnating the polymerization initiator and the styrene monomer in the seed particle at a temperature at which polymerization of the styrene monomer does not substantially proceed, the amount of the styrene monomer is 20 to 200 parts by weight based on 100 parts by weight of the seed particle; and in an additional impregnation polymerization step of graft polymerizing the styrene monomer on the styrene-based resin, the addition amount of the styrene monomer is 50 to 700 parts by weight based on 100 parts by weight of the seed particle, and the content of the styrene monomer in the seed particle is held at 10% by weight or less.

Provided is a solid phase carrier which has high water dispersibility, allows facilitated binding of a ligand to a reactive functional group, and exhibits suppressed non-specific adsorption, and with which, in the case of using the solid phase carrier by having a ligand bound thereto, for example, detection of a target substance can be carried out with high sensitivity and low noise. Disclosed is a solid phase carrier having bound thereto a polymer including a structural unit represented by the following Formula (1) and a structural unit represented by the following Formula (2):

##STR00001##

wherein in Formula (1), R.sup.1 represents a hydrogen atom or a methyl group; and R.sup.2 represents an organic group having a zwitterionic structure,

##STR00002## in Formula (2), R.sup.3 represents a hydrogen atom or a methyl group R.sup.4 represents —(C═O)—O—*, —(C═O)—NR.sup.6—* (wherein R.sup.6 represents a hydrogen atom or a methyl group; and the symbol * represents a position of bonding to R.sup.5 in Formula (2)), or a phenylene group; in a case in which R.sup.4 represents —(C═O)—O—*, R.sup.5 represents a hydrogen atom, or an organic group having a reactive functional group, and in a case in which R.sup.4 represents —(C═O)—NR.sup.6—* or a phenylene group, R.sup.5 represents an organic group having a reactive functional group, provided that R.sup.5 is not an organic group having a zwitterionic structure.

Provided is a solid phase carrier which has high water dispersibility, allows facilitated binding of a ligand to a reactive functional group, and exhibits suppressed non-specific adsorption, and with which, in the case of using the solid phase carrier by having a ligand bound thereto, for example, detection of a target substance can be carried out with high sensitivity and low noise. Disclosed is a solid phase carrier having bound thereto a polymer including a structural unit represented by the following Formula (1) and a structural unit represented by the following Formula (2):

##STR00001##

wherein in Formula (1), R.sup.1 represents a hydrogen atom or a methyl group; and R.sup.2 represents an organic group having a zwitterionic structure,

##STR00002## in Formula (2), R.sup.3 represents a hydrogen atom or a methyl group R.sup.4 represents —(C═O)—O—*, —(C═O)—NR.sup.6—* (wherein R.sup.6 represents a hydrogen atom or a methyl group; and the symbol * represents a position of bonding to R.sup.5 in Formula (2)), or a phenylene group; in a case in which R.sup.4 represents —(C═O)—O—*, R.sup.5 represents a hydrogen atom, or an organic group having a reactive functional group, and in a case in which R.sup.4 represents —(C═O)—NR.sup.6—* or a phenylene group, R.sup.5 represents an organic group having a reactive functional group, provided that R.sup.5 is not an organic group having a zwitterionic structure.

Provided is a solid phase carrier which has high water dispersibility, allows facilitated binding of a ligand to a reactive functional group, and exhibits suppressed non-specific adsorption, and with which, in the case of using the solid phase carrier by having a ligand bound thereto, for example, detection of a target substance can be carried out with high sensitivity and low noise. Disclosed is a solid phase carrier having bound thereto a polymer including a structural unit represented by the following Formula (1) and a structural unit represented by the following Formula (2):

##STR00001##

wherein in Formula (1), R.sup.1 represents a hydrogen atom or a methyl group; and R.sup.2 represents an organic group having a zwitterionic structure,

##STR00002## in Formula (2), R.sup.3 represents a hydrogen atom or a methyl group R.sup.4 represents —(C═O)—O—*, —(C═O)—NR.sup.6—* (wherein R.sup.6 represents a hydrogen atom or a methyl group; and the symbol * represents a position of bonding to R.sup.5 in Formula (2)), or a phenylene group; in a case in which R.sup.4 represents —(C═O)—O—*, R.sup.5 represents a hydrogen atom, or an organic group having a reactive functional group, and in a case in which R.sup.4 represents —(C═O)—NR.sup.6—* or a phenylene group, R.sup.5 represents an organic group having a reactive functional group, provided that R.sup.5 is not an organic group having a zwitterionic structure.

A resin composition is provided. The resin composition comprises: (A) a compound having a structure of formula (I), ##STR00001## wherein R.sub.1 is an organic group; and (B) a vinyl-containing elastomer, wherein the weight ratio of the compound having the structure of formula (I) to the vinyl-containing elastomer is 20:1 to 1:1.

A resin composition is provided. The resin composition comprises: (A) a compound having a structure of formula (I), ##STR00001## wherein R.sub.1 is an organic group; and (B) a vinyl-containing elastomer, wherein the weight ratio of the compound having the structure of formula (I) to the vinyl-containing elastomer is 20:1 to 1:1.

This invention relates to compositions and medical devices comprising anti-microbial active particles, for inhibiting microbial growth. This invention further provides methods of making such compositions and medical devices.

This invention relates to compositions and medical devices comprising anti-microbial active particles, for inhibiting microbial growth. This invention further provides methods of making such compositions and medical devices.

Described herein are a water-borne core-shell polymer, a method for preparing the same, and the applications thereof. Also described herein is a water-borne styrene/vinyl acetate (St/Vae) core-shell polymer which is suitable for corrugated board ink applications. The water-borne emulsion containing the core-shell polymer shows superior covering property and color strength.