This application discloses prodrug-based thermosensitive gel (“ProGel”) comprised of conjugates of dmg molecules with water-soluble polymeric carriers, which are capable of controlled release of the dmg molecules into the tissue of a subject. Use of the ProGel-Drug conjugates for treatment of various diseases or disorders and methods of preparing them are also disclosed.

Provided are a curable composition including, a block copolymer including a block A which has a constitutional unit having an ethylenically unsaturated group in a side chain of a polymer compound, a pigment, and, a photopolymerization initiator, in which a content of a polymerizable compound is 15 mass % or less with respect to a total solid content of the curable composition; a cured product of the curable composition; a color filter including the cured product; and a solid-state imaging element or an image display device including the color filter.

The present application relates to a block copolymer and a use thereof. The present application can provide a laminate which is capable of forming a highly aligned block copolymer on a substrate and thus can be effectively applied to production of various patterned substrates, and a method for producing a patterned substrate using the same.

The present disclosure provides compounds and nanostructures having one or more quaternary ammonium salts, compositions including the compounds and nanostructures, and methods useful for treating conditions using the compounds, nanostructures, and compositions. In at least one aspect, a compound is represented by formula (I): ##STR00001##
or a pharmaceutically acceptable salt thereof, wherein: Q is fluoro, chloro, bromo, or iodo; each of s, b, and n is independently an integer from about 10 to about 100; and each of v, j, p, z, q, x and m is independently an integer from 1 to about 20.

Disclosed are chelating co-polymer compositions that are soluble in aqueous media and chelate essential metals, methods of preparation and uses thereof. The chelating compositions are comprised of two or more different monomers, at least one of which possesses metal binding or metal chelating activity. The chelating compositions are synthesized by reversible addition-fragmentation transfer (RAFT) polymerization with the aid of a suitable RAFT-mediating agent. Also described are chelating compositions that comprise hydroxypyridinone chelating groups. The ability of the chelating compositions to bind metals affects the activity of a living cells and organisms, which require the metals for cellular functions.

A block copolymer comprising at least three polymer blocks, block A, block B and block C, wherein block A comprises polymerised monomer A′ or polymerised monomers A′ and C′; block B comprises polymerised monomer B′; and block C comprises polymerised monomer C′ or polymerised monomers A′ and C′; wherein monomers A′, B′ and C′ are defined herein.

A block copolymer having the general formula as formula (1): mediator-P.sub.2-P.sub.1-X, formula (1), and the chemical structural formula is

##STR00001##

formula (2), in which the mediator in formula (1) and formula (2) is a regulator, which is a conjugated seven-membered ring structure, P.sub.1 is a first polymer which may be a conjugated or non-conjugated olefin monomer, R.sub.1 is the functional group of P.sub.1, n is the number of the monomer of P.sub.1, which is a positive integer and the range is 10˜1,500. P.sub.2 is a second polymer, m is the number of the monomer of P.sub.2, which is a positive integer and the range is 10˜1,500, and X is the end-functional group of the block copolymer.

The present invention relates to a method for preparing an aqueous dispersion of water-soluble polymers, which comprises a step (E) of radical polymerization, wherein the following are brought into contact in an aqueous medium (M) in which the synthesised polymer is not soluble: at least one ethylenically unsaturated monomer which is soluble in the aqueous medium (M); at least one source of free radicals; and a reactive stabiliser which comprises: a polymer chain (CP) which is soluble in the medium (M), a group (G) providing the radical polymerization of step (E) with a living and controlled nature, such as, for example, a group carrying a thiocarbonylthio —S(C═S)— group.

The present invention relates to the use of a block polymer as fluid loss control agent in a fluid injected under pressure into an oil-bearing rock, where: the fluid comprises solid particles and/or is brought into contact with solid particles within the oil-bearing rock subsequent to its injection, the polymer comprises: a first block which is adsorbed on at least a portion of the particles; and a second block with a composition distinct from that of the first and with a weight-average molecular weight of greater than 10 000 g/mol, for example of greater than 100 000 g/mol, and which is soluble in the fluid.

A composition for treating a formation includes a surfactant including an amphiphilic block copolymer having a first block and a second block and an acid. The amphiphilic block copolymer is a reaction product of a first monomer and a second monomer via a reversible addition-fragmentation chain transfer polymerization (RAFT) in a two-step reaction using a chain transfer agent (CTA) and a radical initiator. The surfactant favors adsorption onto a surface of the formation such that a temporary barrier is formed, thereby attenuating a reaction rate between the acid and the formation.