The present invention relates to a manufacturing method of a polyalkylene carbonate resin capable of suppressing agglomeration among catalyst particles during polymerization to maintain an excellent catalytic activity in a polymerization process, wherein the manufacturing method of a polyalkylene carbonate resin may include polymerizing epoxide and a monomer including carbon dioxide in the presence of a zinc dicarboxylate-based organic zinc catalyst and a dispersant, and the dispersant may include at least one selected from the group consisting of C1-C10 alkyl acrylate, C1-C10 alkyl methacrylate, C1-C20 monocarboxylic acid having an oxo group in a molecular structure, and a polyether-based polymer having C2-C6 alkylene oxide repeating units.

The present invention relates to a polymer comprising repeating units consisting of a substituted pyrrole ring. In particular, the repeating units consist of substituted pyrrole containing polar groups capable of interacting with carbon allotropes such as carbon nanotubes, graphene or nanographites, in order to improve the chemical-physical characteristics of the allotropes mainly by increasing their dispersibility and stability in liquid media and in polymer matrices. The invention also relates to products of addition of these polymers with carbon allotropes in order to obtain easily dispersible macromolecules.

Provided are an aliphatic polycarbonate-polyurethane composition and an aliphatic polycarbonate-polyurethane polymer using the same.

Nanoparticles comprise a drug, a first block polymer and a second block polymer. The first block polymer has a poly(ethylene oxide) (PEO) block and a polycarbonate block bearing a side chain aromatic nitrogen-containing heterocycle (N-heterocycle). The N-heterocycle can be in the form of a base, a hydrosalt of the base, a sulfobetaine adduct of the base, or a combination thereof. The second block polymer has a PEO block and a polycarbonate block bearing a side chain catechol group, which can be present as a catechol, oxidized form of a catechol, and/or a polymerized form of a catechol. The nanoparticles can be dispersed in water and are capable of controlled release of the drug.

The present invention provides novel metal complexes, methods of making, and methods of using the same.

The invention relates to a method for producing polyether carbonate polyols, (i) one or more alkylene oxide(s) and carbon dioxide being added to one or more H-functional starter substance(s) in the presence of a double metal cyanide catalyst or in the presence of a metal complex catalyst based on the metals zinc and/or cobalt, a reaction mixture containing the polyether carbonate polyol being obtained, characterized in that (ii) at least one component K is added to the obtained reaction mixture containing the polyether carbonate polyol, wherein component K is selected from at least one compound that contains a phosphorus-oxygen bond or a compound of phosphorus that can form one or more P—O bonds by reaction with OH-functional compounds.

Disclosed are a thermoplastic resin composition which, through combination of certain compatibilizers, satisfies high-gloss and high-impact properties, does not generate weld lines and flow marks, and furthermore, has appropriate impact strength and can sufficiently satisfy scratch resistance required for adoption in actual products, and a product using the same. The present invention provides a polycarbonate-based thermoplastic resin composition including 5-28 wt % of a polycarbonate thermoplastic resin; 55-80 wt % of a polymethylmethacrylate copolymer; 1-20 wt % of a styrene-acrylonitrile copolymer; and 1-20 wt % of a styrene-methylmethacrylate-butyl-acrylate copolymer, and a product using the same.

Disclosed are a thermoplastic resin composition which, through combination of certain compatibilizers, satisfies high-gloss and high-impact properties, does not generate weld lines and flow marks, and furthermore, has appropriate impact strength and can sufficiently satisfy scratch resistance required for adoption in actual products, and a product using the same. The present invention provides a polycarbonate-based thermoplastic resin composition including 5-28 wt % of a polycarbonate thermoplastic resin; 55-80 wt % of a polymethylmethacrylate copolymer; 1-20 wt % of a styrene-acrylonitrile copolymer; and 1-20 wt % of a styrene-methylmethacrylate-butyl-acrylate copolymer, and a product using the same.

Amphiphilic block copolymers (BCPs) were prepared comprising a poly(ethylene oxide) block and a biodegradable polycarbonate block functionalized with disulfide groups and carboxylic acid groups. The BCPs form self-assembled micellar particles in aqueous solution that can be loaded with hydrophobic drugs for therapeutic drug delivery. The loaded particles have small particle sizes (<100 nm), narrow particle size distributions, and high drug loading capacity (up to about 50 wt %) based on total dry weight of the loaded particles. Particles loaded with DOX released the DOX in response to changes in pH and glutathione (GSH) redox chemistry. The loaded particles efficiently delivered and released DOX within tumor cells, effectively suppressing growth of the tumor cells at a similar or even lower drug concentration than free DOX. Blank particles containing no DOX did not induce cytotoxicity to cells.

Amphiphilic block copolymers (BCPs) were prepared comprising a poly(ethylene oxide) block and a biodegradable polycarbonate block functionalized with disulfide groups and carboxylic acid groups. The BCPs form self-assembled micellar particles in aqueous solution that can be loaded with hydrophobic drugs for therapeutic drug delivery. The loaded particles have small particle sizes (<100 nm), narrow particle size distributions, and high drug loading capacity (up to about 50 wt %) based on total dry weight of the loaded particles. Particles loaded with DOX released the DOX in response to changes in pH and glutathione (GSH) redox chemistry. The loaded particles efficiently delivered and released DOX within tumor cells, effectively suppressing growth of the tumor cells at a similar or even lower drug concentration than free DOX. Blank particles containing no DOX did not induce cytotoxicity to cells.