C08G69/44

Drug delivery system for delivery of acid sensitivity drugs

The present invention relates to a drug delivery system comprising a core and a shell in which the core comprises a hydrolytically degradable polymer X which polymer backbone comprises pendant ester and acid functionalities and in which the shell comprises a hydrolytic degradable polymer Y. The hydrolytic degradable polymers X and Y are different polymers. Polymer X further comprises amino-acids in the polymer backbone and degrades via zero order degradation kinetics for a period of at least 3 months. Polymer Y degrades via auto-acceleration degradation kinetics.

THERMALLY CROSSLINKABLE COMPOSITION FOR USE AS A BINDER IN A BINDER JETTING PROCESS
20210387409 · 2021-12-16 ·

The present invention relates to the use of a liquid composition comprising one or more monomers for the production of a polyester, of a polyamide or of a polyesteramide, where at least one monomer is at least trifunctional, as binder in the binder-jetting process. The invention further relates to a process for the production of a shaped body by binder jetting.

THERMALLY CROSSLINKABLE COMPOSITION FOR USE AS A BINDER IN A BINDER JETTING PROCESS
20210387409 · 2021-12-16 ·

The present invention relates to the use of a liquid composition comprising one or more monomers for the production of a polyester, of a polyamide or of a polyesteramide, where at least one monomer is at least trifunctional, as binder in the binder-jetting process. The invention further relates to a process for the production of a shaped body by binder jetting.

Biodegradable polyionenes

Synthesis of polyionenes with built-in degradable linkers through addition polymerization of a novel class of degradable A.sub.2-type monomers (d-A.sub.2), and their use as antimicrobial agents are disclosed. A library of biodegradable polyionenes and Gemini-surfactants made from d-A.sub.2 monomers are also disclosed. These materials have potent and broad spectrum of antimicrobial activity with high selectivity over mammalian cells.

Biodegradable polyionenes

Synthesis of polyionenes with built-in degradable linkers through addition polymerization of a novel class of degradable A.sub.2-type monomers (d-A.sub.2), and their use as antimicrobial agents are disclosed. A library of biodegradable polyionenes and Gemini-surfactants made from d-A.sub.2 monomers are also disclosed. These materials have potent and broad spectrum of antimicrobial activity with high selectivity over mammalian cells.

METHOD OF PREPARING POLYESTER ELASTOMER MELTBLOWN NONWOVEN FABRIC MEMBRANE WITH POROUS AND HIGH BONDING STRENGTH

A method of preparing polyester elastomer meltblown nonwoven fabric membrane with porous and high bonding strength includes the following steps of: (a) Adding a reaction solvent to a reaction solvent to thermoplastic polyester elastomer (TPEE) powder or granules to prepare a solvent mixture. (b) Adding a modifier to the solvent mixture, and mixing uniformly to prepare a first mixture, the modifier includes at least one of o-xylylenediamine, m-xylylenediamine, alpha, alpha′-diamino-p-xylene, 2,3,5,6-Tetrachloro-p-xylene-alpha,alpha′-diamine, and 1,3,5,7-Tetraazatricyclodecane. (c) Adding an initiator to the first mixture, and mixing uniformly to prepare a second mixture. (d) Drying the second mixture to form a masterbatch, and (e) preparing the polyester elastomer meltblown nonwoven fabric membrane by passing the masterbatch through a meltblown process.

BIODEGRADABLE POLYESTERAMIDE USED FOR THE TREATMENT OF ARTHRITIC DISORDERS

The present invention relates to a formulation sized for injection comprising a biodegradable polyesteramide co-polymer comprising at least a diol of bicyclic-1,4:3,6-dianhydrohexitol and analgesics for use in the treatment of arthritic disorders. More specific the invention relates to a formulation comprising injectable microparticle according to claim 1 wherein the polyesteramide co-polymer further comprises a diacid, a diol different from bicyclic-1,4:3,6-dianhydrohexitol and at least two different amino-acids. The formulation is used to treat pain or inflammation in a patient comprising administering to said patient a therapeutically effective amount of the formulation once or twice a year.

BIODEGRADABLE POLYESTERAMIDE USED FOR THE TREATMENT OF ARTHRITIC DISORDERS

The present invention relates to a formulation sized for injection comprising a biodegradable polyesteramide co-polymer comprising at least a diol of bicyclic-1,4:3,6-dianhydrohexitol and analgesics for use in the treatment of arthritic disorders. More specific the invention relates to a formulation comprising injectable microparticle according to claim 1 wherein the polyesteramide co-polymer further comprises a diacid, a diol different from bicyclic-1,4:3,6-dianhydrohexitol and at least two different amino-acids. The formulation is used to treat pain or inflammation in a patient comprising administering to said patient a therapeutically effective amount of the formulation once or twice a year.

POLYMER, FIBER AND TEXTILE

A polymer includes a repeating unit M and a repeating unit D, the repeating unit M is —COC.sub.6H.sub.6CONHCH.sub.2CH.sub.2O—, the repeating unit D is —COC.sub.6H.sub.6COOCH.sub.2CH.sub.2O—, and a molar ratio of the repeating unit M to the repeating unit D is 1:6 to 1:999.

Composite textile product

A composite textile product includes a polyamide textile layer and a polyamide film. The polyamide film is bonded to the polyamide textile layer. A thickness of the polyamide textile layer is between 0.1 mm and 0.3 mm. The polyamide film has an average pore size ranging from 10 μm to 150 μm. A thickness of the polyamide film is between 0.01 mm and 0.1 mm. Wherein the polyamide film comprises a copolymer material, and the copolymer material includes a polyamide section and a polyether section.