Disclosed are methods, compositions, reagents, systems, and kits to prepare and utilize branched multi-functional macromonomers, which contain a ring-opening metathesis polymerizable norbornene group, one or more reactive sites capable of undergoing click chemistry, and a terminal acyl group capable of undergoing a coupling reaction; branched multi-cargo macromonomers; and the corresponding polymers are disclosed herein. Various embodiments show that the macromonomers and polymers disclosed herein display unprecedented control of cargo loading of agents. These materials have the potential to be utilized for the treatment of diseases and conditions such as cancer and hypertension.

Disclosed are methods, compositions, reagents, systems, and kits to prepare and utilize branched multi-functional macromonomers, which contain a ring-opening metathesis polymerizable norbornene group, one or more reactive sites capable of undergoing click chemistry, and a terminal acyl group capable of undergoing a coupling reaction; branched multi-cargo macromonomers; and the corresponding polymers are disclosed herein. Various embodiments show that the macromonomers and polymers disclosed herein display unprecedented control of cargo loading of agents. These materials have the potential to be utilized for the treatment of diseases and conditions such as cancer and hypertension.

The present invention relates to cross polymers composed at least of polysaccharides and polyamino acids, and more particularly to hydrogels composed of said cross polymers. The invention also relates to a process for preparing them, as well as their use in the delivery of active agents for pharmaceutical, diagnostic and/or dermo-cosmetic applications.

Methodology was developed for transformation of methionine residues into homocysteine derivatives. Methionine residues can undergo alkylation reactions at low pH to yield sulfonium ions, which can then be selectively demethylated to give alkyl homocysteine residues. This process tolerates many functional groups.

Methodology was developed for transformation of methionine residues into homocysteine derivatives. Methionine residues can undergo alkylation reactions at low pH to yield sulfonium ions, which can then be selectively demethylated to give alkyl homocysteine residues. This process tolerates many functional groups.

Techniques regarding guanidinium functionalized polylysine polymers that can have antimicrobial and/or anticancer activity are provided. For example, one or more embodiments described herein can comprise a chemical composition, which can comprise a polymer comprising a molecular backbone covalently bonded to a pendent guanidinium functional group, wherein the molecular backbone can comprise a polylysine structure.

The present invention discloses novel calibrants containing between 1 and 5 iodine atoms and methods of making them using linear polymers, hyperbranched polymers, and biological polymers (including but not limited to proteins and peptides.) Methods of using the calibrants are also disclosed, such as mass spectrometry. The novel calibrants disclosed herein have a more cost- and time-efficient synthesis than other calibrants.

The present invention discloses novel calibrants containing between 1 and 5 iodine atoms and methods of making them using linear polymers, hyperbranched polymers, and biological polymers (including but not limited to proteins and peptides.) Methods of using the calibrants are also disclosed, such as mass spectrometry. The novel calibrants disclosed herein have a more cost- and time-efficient synthesis than other calibrants.

A recycling process for a polyamide waste material includes the following steps: adding a polyamide waste material into a mixed solvent to obtain a solution, heating the solution to 50° C. to a reflux temperature of the solution, conducting stirring for dissolution, and then conducting decolorization treatment and filtration to obtain a polyamide solution; and adding the polyamide solution into water, precipitating polyamide as a solid in deionized water, and conducting separation to obtain recycled polyamide. The mixed solvent includes, in parts by weight, 10-30 parts of phenol and 15-40 parts of toluene.

A recycling process for a polyamide waste material includes the following steps: adding a polyamide waste material into a mixed solvent to obtain a solution, heating the solution to 50° C. to a reflux temperature of the solution, conducting stirring for dissolution, and then conducting decolorization treatment and filtration to obtain a polyamide solution; and adding the polyamide solution into water, precipitating polyamide as a solid in deionized water, and conducting separation to obtain recycled polyamide. The mixed solvent includes, in parts by weight, 10-30 parts of phenol and 15-40 parts of toluene.