The invention provides an ultra-small nano metal organic framework material and a preparation method thereof. The MOFs material is prepared from a low-cost metal source and organic ligands through solvothermal reaction, wherein metal ions in the metal source are at least two of ferric ions, bivalent copper ions or bivalent zinc ions; the ligands are at least two of terephthalic acid, 2-aminoterephthalic acid, meso-tetra (4-carboxyphenyl) porphin, 2-nitroterephthalic acid, 2-hydroxyterephthalic acid and trimesic acid; the solvent is formed by mixing ethanol and o-dichlorobenzene according to the volume ratio of (1-3):1. The particle size of the prepared MOFs material is 2-10 nm, and the prepared MOFs material is high in dispersity, specific surface area and activity. The MOFs material aqueous solution can generate a large amount of active oxygen in an ultrasonic environment, and has extremely high medical value.

A method for enhancing the conductivity of MOF-5 by the development of an MOF-5 polymer composite material. The composite material incorporates a conductive polymer, preferably polyaniline, in the solvo-thermal synthesis pathway of MOF-5. The electrically conductive MOF-5 composite exhibits electric conductivity three orders of magnitude higher than that of MOF-5 while maintaining the crystallinity, robustness, and thermal stability of MOF-5.

A block copolymer of the formula R.sub.f-PEG-PAA is disclosed, where R.sub.f comprises a perfluoroalkyl group having at least 3 carbon atoms, bound to an ether oxygen atom directly or through a substituted or unsubstituted alkylene group, PEG is a poly(alkylene glycol) unit having a weight average molecular weight or number average molecular weight of from 1 to 20 kDa, and PAA is one or more poly([meth]acrylic acid) units having a total weight average molecular weight or number average molecular weight of from 0.3 to 10 kDa. A polymer mixture including the block copolymer, a co-hydrogel and a drug delivery vehicle including the polymer mixture, and methods of synthesizing the block copolymer, forming a sol-gel two-phase co-hydrogel, forming a drug delivery vehicle, and delivering a drug to a patient in need thereof are also disclosed.

Provided are supramolecular polypseudorotaxane hydrogel compositions and 3-D structures capable of reversible 3-D structural deformation which include (a) a solvent; (b) an at least partially linear polymer, where the polymer further comprises groups capable of covalent crosslinking between the polymers; (ii) at least one first macrocyclic ring which forms a pseudorotaxane with a polymer in the polymer network; and (iii) at least one second macrocyclic ring that does not form the pseudorotaxane. The hydrogel composition has a viscosity which allows for 3-D printing of the hydrogel to form a 3-D structure, and a storage (elastic) modulus after crosslinking that allows for the 3-D structure to undergo reversible 3-D structural deformation upon change of solvent conditions. Also provided are methods of manufacturing the compositions and 3-D structures.

The present invention relates to novel amphiphilic dendrimers, hereafter denoted Dendri-TAC. The present invention also relates to perfluorocarbon nanoemulsions stabilized by these amphiphilic dendrimers and their uses for in vivo diagnostic and/or for therapy, notably as theranostic tools, for detection and/or treatment of cancer.

Described herein are associative polymers capable of controlling one or more physical and/or chemical properties of non--polar compositions and related compositions, methods and systems.

The present invention relates to a ligand-containing conjugated microporous polymer, which is obtained by covalent coupling of a conjugated microporous polymer and a uranium complexing ligand. The conjugated microporous polymer comprises an aromatic ring and/or a heterocyclic ring. The uranium complexing ligand is selected from the group consisting of a compound with a group containing phosphorus, a compound with a group containing nitrogen, and a compound with a group containing sulfur. The invention further provides use of the ligand-containing conjugated microporous polymer as a uranium adsorbent. The ligand-containing conjugated microporous polymer the invention is capable of adsorbing the radioactive element uranium in strongly acidic and strong-radiation environments.

A nested capsule having a first capsule held within a second capsule. Each of the first and second capsules has a shell that is a supramolecular cross-linked network, such as a cucurbituril supramolecular cross-linked network. Each capsule shell is obtained or is obtainable from the complexation of a composition including a host, such as cucurbituril, and one or more building blocks having suitable guest functionality for the host, thereby to form a supramolecular cross-linked network. The nested capsules are suitable for delivering and selectively releasing an encapsulant at a location.

Described herein are associative polymers capable of controlling a physical and/or chemical property of non-polar compositions and related compositions, methods and systems. Associative polymers herein described have a non-polar backbone and functional groups presented at ends of the non-polar backbone, with a number of the functional groups presented at the ends of the non-polar backbone formed by associative functional groups capable of undergoing an associative interaction with another associative functional group with an association constant (k) such that the strength of each associative interaction is less than the strength of a covalent bond between atoms and in particular less than the strength of a covalent bond between backbone atoms.

Described herein are associative polymers capable of controlling a physical and/or chemical property of non-polar compositions and related compositions, methods and systems. Associative polymers herein described have a non-polar backbone and functional groups presented at ends of the non-polar backbone, with a number of the functional groups presented at the ends of the non-polar backbone formed by associative functional groups capable of undergoing an associative interaction with another associative functional group with an association constant (k) such that the strength of each associative interaction is less than the strength of a covalent bond between atoms and in particular less than the strength of a covalent bond between backbone atoms.