Patent classifications
C08J3/28
LIGHT-ACTIVATED COUPLING OF OLIGONUCLEOTIDES TO POLYMERS
Provided herein are various examples of a method of coupling oligonucleotides to a polymer. The method may include selectively irradiating first inactive moieties in a one or more first region of a polymer with light, while not irradiating second inactive moieties in a one or more second region of the polymer, to generate first active moieties in the one or more first region of the polymer. The method may also include coupling the first active moieties to first oligonucleotides. The method may further include irradiating the second inactive moieties in the one or more second region of the polymer with light to generate second active moieties in the one or more second region of the polymer. The method may also include coupling the second active moieties to second oligonucleotides.
LIGHT-ACTIVATED COUPLING OF OLIGONUCLEOTIDES TO POLYMERS
Provided herein are various examples of a method of coupling oligonucleotides to a polymer. The method may include selectively irradiating first inactive moieties in a one or more first region of a polymer with light, while not irradiating second inactive moieties in a one or more second region of the polymer, to generate first active moieties in the one or more first region of the polymer. The method may also include coupling the first active moieties to first oligonucleotides. The method may further include irradiating the second inactive moieties in the one or more second region of the polymer with light to generate second active moieties in the one or more second region of the polymer. The method may also include coupling the second active moieties to second oligonucleotides.
METHOD FOR MANUFACTURING LOW-MOLECULAR-WEIGHT POLYTETRAFLUOROETHYLENE
The invention relates to a method for manufacturing low-molecular-weight polytetrafluoroethylene, comprising: a) a first step of mixing high-molecular-weight polytetrafluoroethylene with at least one additive selected from the group consisting of ethers having formula R.sup.1—O—R.sup.2, wherein R.sup.1 and R.sup.2 are independently selected among C.sub.1-C.sub.10 straight or branched aliphatic group, C.sub.4-C.sub.10 alicyclic or heterocyclic groups, C.sub.5-C.sub.10 aromatic or heteroaromatic groups; (per)fluorinated vinyl ethers; (per)fluorinated olefins; and optionally substituted aromatic hydrocarbons, and b) a second step of irradiating the so obtained mixture with ionizing radiation, said second step b) being carried out substantially in the absence of oxygen.
METHOD FOR MANUFACTURING LOW-MOLECULAR-WEIGHT POLYTETRAFLUOROETHYLENE
The invention relates to a method for manufacturing low-molecular-weight polytetrafluoroethylene, comprising: a) a first step of mixing high-molecular-weight polytetrafluoroethylene with at least one additive selected from the group consisting of ethers having formula R.sup.1—O—R.sup.2, wherein R.sup.1 and R.sup.2 are independently selected among C.sub.1-C.sub.10 straight or branched aliphatic group, C.sub.4-C.sub.10 alicyclic or heterocyclic groups, C.sub.5-C.sub.10 aromatic or heteroaromatic groups; (per)fluorinated vinyl ethers; (per)fluorinated olefins; and optionally substituted aromatic hydrocarbons, and b) a second step of irradiating the so obtained mixture with ionizing radiation, said second step b) being carried out substantially in the absence of oxygen.
High-voltage Components
The present invention relates to high-voltage components, especially for electromobility, containing polymer compositions based on at least one polyester and at least one sulfide containing cerium, and to the use thereof for production of polyester-based high-voltage components or for marking of polyester-based products as high-voltage components by laser.
High-voltage Components
The present invention relates to high-voltage components, especially for electromobility, containing polymer compositions based on at least one polyester and at least one sulfide containing cerium, and to the use thereof for production of polyester-based high-voltage components or for marking of polyester-based products as high-voltage components by laser.
Radiation cured composite materials
Radiation cured composite materials are greatly improved by enhancing the fiber to matrix bond by prewetting the fibers with an interface resin that has a curing agent mixed in with the interface resin. Furthermore, radiation curing the composite material at or near an expected operating temperature of the composite material improves the mechanical properties of the material by reducing thermally induced strains and stresses caused by thermally curing a material and subsequently cooling the material. Adding an interface resin with a curing agent to the fibers allows relatively thick parts, a must faster curing process, a wide variety of inexpensive and easily workable molding materials, the ability to maintain tight tolerances and reduce or eliminate springback, and a radiation cured material that approaches or exceeds the material characteristics of thermally cured composite materials.
Radiation cured composite materials
Radiation cured composite materials are greatly improved by enhancing the fiber to matrix bond by prewetting the fibers with an interface resin that has a curing agent mixed in with the interface resin. Furthermore, radiation curing the composite material at or near an expected operating temperature of the composite material improves the mechanical properties of the material by reducing thermally induced strains and stresses caused by thermally curing a material and subsequently cooling the material. Adding an interface resin with a curing agent to the fibers allows relatively thick parts, a must faster curing process, a wide variety of inexpensive and easily workable molding materials, the ability to maintain tight tolerances and reduce or eliminate springback, and a radiation cured material that approaches or exceeds the material characteristics of thermally cured composite materials.
METHOD FOR PRODUCING POLYALKYLENE OXIDE AND POLYALKYLENE OXIDE
The invention provides a production method that is capable of obtaining a polyalkylene oxide having high whiteness by a simple method, and a polyalkylene oxide.
The method for producing a polyalkylene oxide of the present invention comprises a step of irradiating a high-molecular-weight polyalkylene oxide with radiation in the presence or absence of an antioxidant to obtain a polyalkylene oxide,
wherein the high-molecular-weight polyalkylene oxide has a viscosity in a 1% aqueous solution of 1500 to 16000 mPa.Math.s, when the antioxidant is present, the antioxidant is present in an amount of less than 2000 mass ppm relative to the total mass of the high-molecular-weight polyalkylene oxide, and the following formula (1):
0≤C.sup.3×I×10.sup.−8<30 (1),
wherein C is the concentration of the antioxidant used in the step, and represents the proportion (mass ppm) of the antioxidant relative to the total mass of the polyalkylene oxide, and I represents the irradiation dose (kGy) of the radiation emitted in the above step, is satisfied.
METHOD FOR PRODUCING POLYALKYLENE OXIDE AND POLYALKYLENE OXIDE
The invention provides a production method that is capable of obtaining a polyalkylene oxide having high whiteness by a simple method, and a polyalkylene oxide.
The method for producing a polyalkylene oxide of the present invention comprises a step of irradiating a high-molecular-weight polyalkylene oxide with radiation in the presence or absence of an antioxidant to obtain a polyalkylene oxide,
wherein the high-molecular-weight polyalkylene oxide has a viscosity in a 1% aqueous solution of 1500 to 16000 mPa.Math.s, when the antioxidant is present, the antioxidant is present in an amount of less than 2000 mass ppm relative to the total mass of the high-molecular-weight polyalkylene oxide, and the following formula (1):
0≤C.sup.3×I×10.sup.−8<30 (1),
wherein C is the concentration of the antioxidant used in the step, and represents the proportion (mass ppm) of the antioxidant relative to the total mass of the polyalkylene oxide, and I represents the irradiation dose (kGy) of the radiation emitted in the above step, is satisfied.