Methods for manufacturing, re-activating and using compositions including fibrillated parenchymal cellulose and activator are provided. The activator has a low molecular weight and is used to facilitate reactivation.

The invention relates to a foam material (FP) comprising a polymer composition (C) comprising at least a polyphenylene sulfide polymer (PPS) and at least one functionalized elastomer (E). The present invention also relates to a process for the manufacture of said foam material and to an article (A) including said foam material (FP), for example a composite material.

Disclosed herein are manufacturing/casting processes for the preparation of a foam.

The present invention concerns methods of treating systemic, regional, or local inflammation from a patient suffering or at risk of inflammation comprising administration of a therapeutically effective dose of a sorbent that sorbs an inflammatory mediator in said patient. In some preferred embodiments, the sorbent is a biocompatible organic polymer.

Embodiments herein described provide devices for identifying and collecting rare cells or cells which occur at low frequency in the body of a subject, such as, antigen-specific cells or disease-specific cells. More specifically, the devices are useful for trapping immune cells and the devices contain a physiologically-compatible porous polymer scaffold, a plurality of antigens, and an immune cell-recruiting agent, wherein the plurality of antigens and the immune cell recruiting agent attract and trap the immune cell in the device. Also provided are pharmaceutical compositions, kits, and packages containing such devices. Additional embodiments relate to methods for making the devices, compositions, and kits/packages. Further embodiments relate to methods for using the devices, compositions, and/or kits in the diagnosis or therapy of diseases such as autoimmune diseases or cancers.

Methods and materials used for production of constructs having a porous open or semi-open celled structure. Constructs may include a porous matrix as a base and a biocompatible conformal coating thereon.

Disclosed are a chitin/graphene composite sponge and a preparation method and a use thereof. The method comprises mixing and ball-milling a certain amount of flake graphite and chitin, dissolving a mixture of the flake graphite and the chitin in a NaOH/urea solvent, performing centrifugal separation, dispersing evenly, cross-linking with an epichlorohydrin cross-linking agent, standing, dialyzing, and freeze-drying, thus obtaining the chitin/graphene composite sponge.

The invention relates to a drug delivery device adapted for carrying and delivering both hydrophilic and lipophilic drug molecules. The drug delivery device includes a porous body for adsorption of drug molecules, the body including a plurality of microspheres, and a hydrogel forming cross-links connecting the plurality of microspheres.

The present invention includes a hydrogel and a method of making a porous hydrogel by preparing an aqueous mixture of an uncrosslinked polymer and a crystallizable molecule; casting the mixture into a vessel; allowing the cast mixture to dry to form an amorphous hydrogel film; seeding the cast mixture with a seed crystal of the crystallizable molecule; growing the crystallizable molecule into a crystal structure within the uncrosslinked polymer; crosslinking the polymer around the crystal structure under conditions in which the crystal structure within the crosslinked polymer is maintained; and dissolving the crystals within the crosslinked polymer to form the porous hydrogel.

The present invention concerns methods of treating systemic, regional, or local inflammation from a patient suffering or at risk of inflammation comprising administration of a therapeutically effective dose of a sorbent that sorbs an inflammatory mediator in said patient. In some preferred embodiments, the sorbent is a biocompatible organic polymer.