Patent classifications
C08J2207/10
Biocompatible smart responsive scaffold having interconnected pores
A polymeric scaffold contains pendant liquid crystal side chains and has fully interconnected pores. Such a polymeric scaffold will preferably be 3D in nature and elastomeric, biocompatible and biodegradable. Such 3D liquid crystal elastomer (LCE) scaffolds can be used for various biomedical applications, including cell culture applications. A method for the production of such a polymeric scaffold containing liquid crystals and having interconnected pores is also disclosed that uses a metal foam sacrificial template as a scaffold to produce the polymeric smart response scaffold of the present invention. Consistent and controlled pore sizes result from etching the sacrificial metal foam template away from the polymeric scaffold, permitting the incorporation of growth factors, when needed, for enhancing cell viability and proliferation.
CHEMICALLY MODIFIED SHAPE MEMORY POLYMER EMBOLIC FOAMS WITH INCREASED X-RAY VISUALIZATION
An embodiment includes a system comprising: an iodine containing thermoset open-cell shape memory polymer (SMP) foam that is x-ray visible; wherein (a) the SMP foam is configured to expand from a compressed secondary state to an expanded primary state in response to thermal stimulus, (b) the SMP foam is a poly(urethane-urea-amide). Other embodiments are described herein.
Method for Preparing Porous Scaffold for Tissue Engineering, Cell Culture and Cell Delivery
The present invention relates to a method for preparing a porous scaffold for tissue engineering. It is another object of the present invention to provide a porous scaffold obtainable by the method as above described, and its use for tissue engineering, cell culture and cell delivery. The method of the invention comprises the steps consisting of: a) preparing an alkaline aqueous solution comprising an amount of at least one polysaccharide, an amount of a cross-linking agent and an amount of a porogen agent b) transforming the solution into a hydrogel by placing said solution at a temperature from about 4 C. to about 80 C. for a sufficient time to allow the cross-linking of said amount of polysaccharide and c) submerging said hydrogel into an aqueous solution d) washing the porous scaffold obtained at step c).
Silicone foam compositions rapidly cross-linkable at ambient temperatures and methods of making and using same
Provided are rapidly cross-linkable silicone foam compositions, kits, and methods for filling implanted medical devices in situ or in vivo, the implanted medical devices, including for example, body implants and tissue expanders, the compositions including a platinum divinyl disiloxane complex; a low viscosity vinyl terminated polydimethylsiloxane; a low viscosity hydride terminated polydimethylsiloxane; a silicone cross-linker; and a gas and/or gas-filled microcapsules, where the rapidly cross-linkable silicone foam composition has a viscosity of 150 cPs for 1 min. post-preparation and 300 cPs5 min. post-preparation, at ambient temperature.
COMPOSITIONS AND METHODS FOR PROMOTING HEMOSTASIS
In one aspect, compositions for promoting hemostasis are provided. In some embodiments, the composition comprises a porous non-fibrous substrate impregnated with a hemostatic agent, wherein the porous non-fibrous substrate comprises a hydrophilic polyurethane foam. Methods of promoting hemostasis in a subject using such compositions, and methods of manufacturing such compositions, are also provided.
ACUTE CARE COVER FOR SEVERE INJURIES
A compound made by copolymerizing a poly(N-isopropylacrylamide) chain transfer agent, an acrylate salt, and a polyethylene glycol diacrylate. A compound made by copolymerizing a polyethylene glycol, a glycerol ethoxylate, and an aliphatic diisocyanate.
Foam body, polyolefin-based foam sheet, and complex
A foam body constituted of a 4-methyl-1-pentene-based polymer, in which one or more temperatures showing a maximum value of loss tangent (tan ) of dynamic viscoelasticity, which is obtained by dynamic viscoelasticity measurement conducted under the conditions of a temperature increase rate of 4 C./min, a frequency of 1.59 Hz, and a distortion of 0.1%, exist in at least a range of 10 C. or higher and 100 C. or lower, and the maximum value of the loss tangent is 0.5 or more and 3.5 or less. Another aspect relates to a polyolefin-based foam sheet constituted of a 4-methyl-1-pentene-based polymer, in which the difference in Shore A hardness of at least one surface at different times is defined. A further aspect relates to a complex including a foam body constituted of a 4-methyl-1-pentene-based polymer and a member which is bonded to the foam body and is different from the foam body.
FOAM MATERIALS MADE OF A COMBINATION OF POLY(BIPHENYL ETHER SULFONE) (PPSU) AND POLYETHERSULFONE (PES)
Described herein are foam materials comprising a blend of a poly(biphenyl ether sulfone) (PPSU) and a polyethersulfone polymer (PES) with improved compressive strength and impact performance, a method for their formation, and articles comprising said foam materials for use in various lightweight applications such as transport and building materials.
Peptide-based nanofibrillar materials
Disclosed herein are nanofibrillar materials and aerogel-like materials comprised of nanofibrils, and methods for making such materials.
FOAM BODY, POLYOLEFIN-BASED FOAM SHEET, AND COMPLEX
A foam body constituted of a 4-methyl-1-pentene-based polymer, in which one or more temperatures showing a maximum value of loss tangent (tan ) of dynamic viscoelasticity, which is obtained by dynamic viscoelasticity measurement conducted under the conditions of a temperature increase rate of 4 C./min, a frequency of 1.59 Hz, and a distortion of 0.1%, exist in at least a range of 10 C. or higher and 100 C. or lower, and the maximum value of the loss tangent is 0.5 or more and 3.5 or less. Another aspect relates to a polyolefin-based foam sheet constituted of a 4-methyl-1-pentene-based polymer, in which the difference in Shore A hardness of at least one surface at different times is defined. A further aspect relates to a complex including a foam body constituted of a 4-methyl-1-pentene-based polymer and a member which is bonded to the foam body and is different from the foam body.