The present invention relates to polymer compounds containing hemp and/or components of hemp, and methods for producing such polymer compounds.

According to the present disclosure, a method of preparing polymeric microparticles comprising further crosslinking with an organic crosslinking agent after crosslinking with metal ions, polymeric microparticles, medical compositions, cosmetic compositions, medical articles and cosmetic articles comprising the same can be provided.

The present invention provides a hydrogel platform using, as a substrate, hyaluronic acid (HA) conjugated to a pyrogallol (PG) moiety. The HA-PG conjugate of the present invention can be rapidly crosslinked by two different methods, in each of which an oxidizing agent is used or a pH is adjusted. The hydrogel of the present invention can not only have excellent biocompatibility, but also can have efficiently controlled physical characteristics such as a crosslinking rate, elasticity, and adhesive strength, depending on each crosslinking method. On the basis of such excellent stability and functionality, the hydrogel of the present invention can be used in various fields including drug delivery, biopharmaceutical materials such as a wound healing agent or anti-adhesive agent, medicines, and cosmetic products.

A method of foam production is described. The method includes providing a foam precursor including one or more components, the one or more components including at least one of chitin, chitosan, or chitosan oligosaccharide and a solvent. The method further comprises exposing the foam precursor to radiation. The radiation is of a wavelength to heat the foam precursor. A system for foam produced is described, the system including a mixer configured to output a foam precursor including one or more components. The one or more components include at least one of chitin, chitosan, or chitosan oligosaccharide. The system further includes a radiation emitting system positioned to receive the foam precursor from the mixer and expose the foam precursor to radiation to heat the foam precursor to form a solid foam.

A foam is described. The foam comprising a polymer matrix including at least one of chitin, chitosan, or chitosan oligosaccharide. The polymer matrix is porous. The foam further comprising alginate. The foam has a density of less than 1 g/cm.sup.3. A method of making foam is described. The method comprising dissolving at least one of chitin, chitosan, or chitosan oligosaccharide in a first solution, dissolving alginate in a second solution that is alkaline and separate from the first solution, mixing the first solution and the second solution together to form a foam precursor, and drying the foam precursor to form the foam.

The present disclosure discloses a preparation method and use of a crosslinked hydrogel for muscle stem cell culture, and belongs to the technical field of biological food materials. Chitosan, alginate, dextran and Ca.sup.2+ are crosslinked through physical crosslinking to form a double-network hydrogel with a high mechanical strength, the hydrogel is coated with heparin and collagen through dip coating, such that the hydrogel can immobilize growth factors and adhere to cells. Meanwhile, extracted primary muscle stem cells are inoculated onto the hydrogel and cultured in a growth medium (79% of DMEM, 10% of FBS and 1% of double antibodies) for 24 h. The cells are cultured in an incubator with a differential medium (97% of DMEM, 2% of horse serum and 1% of double antibodies) for 7 d. The hydrogel can enhance the absorption to nutrient substances by the muscle stem cells and facilitate growth of the muscle stem cells. The double-network hydrogel has the potential to be a scaffold for growth of muscle stem cells for cultured meat from stem cells.

The present application relates to the technical field of wastewater treatment and rapid pollutant detection, in particular to a chitosan-polyacrylamide composite porous hydrogel, preparation and use thereof, and a metal ion-adsorbing and detecting reagent and method. The chitosan-polyacrylamide composite porous hydrogel of the present application is prepared by in situ polymerization of a chitosan sol, an acrylamide, a crosslinking agent and a surfactant into a mixed solution comprising liquid droplets, followed by steps of curing, washing, and freeze-drying. The present application further provides a metal ion-detecting reagent, which is obtained by adsorbing a color developing agent into the chitosan-polyacrylamide composite porous hydrogel as described above, wherein the color developing agent is a dye that changes color when encountering metal ions. The chitosan-polyacrylamide composite porous hydrogel of the present application has balanced mechanical properties and porosity.

The invention discloses a modified chitosan-LZM-CA composite antibacterial cling film optimized by response surface methodology and the preparation method and application thereof, relates to the technical field of food packaging materials. The invention provides freshwater crayfish as the research object, and adopts the modified chitosan, lysozyme (LZM), a good film-forming material carrageenan (CA) as the composite antibacterial cling film materials, and through the response surface experimental design to determine the best ratio of modified chitosan-LZM-CA composite antibacterial cling film. Furthermore, the TVB-N value and the change value of the total number of bacterial colonies of the freshwater crayfish with the composite antibacterial cling film during refrigeration, can be regarded as indicators to examine the preservation effect, providing a theoretical basis of the chitosan composite film preservation technology development and application for freshwater crayfish and other aquatic products.

The invention relates to a hydrogel product comprising glycosaminoglycan molecules as the swellable polymer, wherein the glycosaminoglycan molecules are covalently crosslinked via crosslinks comprising a spacer group selected from the group consisting of di-, tri-, tetra-, and oligosaccharides.

Hydrogels that degrade under appropriate conditions of pH and temperature by virtue of crosslinking compounds that cleave through an elimination reaction are described. The hydrogels may be used for delivery of various agents, such as pharmaceuticals.