A medical device and a method of manufacturing the same which excels in lubricity under severe conditions are provided. The medical device according to the present disclosure is inserted into a living body. The medical device includes a resin coating layer that includes a maleic acid polymer substance and is provided on a surface of a base member. The resin coating layer is formed by covalently bonding the maleic acid polymer substance to a reactive functional group which exists on at least the surface of the base member of the medical device. A ratio of a peak height of carboxylate with respect to a total peak height of carboxylic acid ester and a carboxylic acid in the maleic acid polymer substance ranges from 1.2 to 1.7 when being measured through infrared spectroscopy (IR method).

A medical elongated body including a tubular main body and a hub connected to the tubular main body. The medical elongated body includes a strain relief supported by a distal portion of the hub. The strain relief surrounds a predetermined range of the proximal portion of the tubular main body. The medical elongated body includes a hydrophilic lubricating coating layer and a temperature responsive lubricating coating layer on the outer surface of the tubular main body, the temperature responsive lubricating coating layer being proximal to the hydrophilic lubricating coating layer. The hydrophilic lubricating coating layer exhibits lubricating characteristics when wet. The temperature responsive lubricating coating layer exhibits hydrophilic characteristics and lubricating characteristics at a temperature lower than a critical temperature when wet and exhibits hydrophobic characteristics and non-lubricating characteristics at a temperature equal to or higher than the critical temperature when wet.

A medical elongated body including a tubular main body and a hub connected to the tubular main body. The medical elongated body includes a strain relief supported by a distal portion of the hub. The strain relief surrounds a predetermined range of the proximal portion of the tubular main body. The medical elongated body includes a hydrophilic lubricating coating layer and a temperature responsive lubricating coating layer on the outer surface of the tubular main body, the temperature responsive lubricating coating layer being proximal to the hydrophilic lubricating coating layer. The hydrophilic lubricating coating layer exhibits lubricating characteristics when wet. The temperature responsive lubricating coating layer exhibits hydrophilic characteristics and lubricating characteristics at a temperature lower than a critical temperature when wet and exhibits hydrophobic characteristics and non-lubricating characteristics at a temperature equal to or higher than the critical temperature when wet.

A biocompatible material, which has excellent film formation properties and resistance to water dissolution, and is easily applied on various bases as a coating, while having excellent antithrombotic properties, and to provide an antithrombotic coating agent and an antithrombotic coating film produced by using the biocompatible material, and a medical device provided with the antithrombotic coating film. A copolymer, containing at least one repeating unit (A) represented by formula (1) (wherein, n represents an integer of 2 to 10 and R.sup.1 represents a methyl group or an ethyl group), and at least one repeating unit (B) represented by formula (2) (wherein R.sup.2 represents an aliphatic hydrocarbon group); an antithrombotic coating agent containing the copolymer and an organic solvent; an antithrombotic coating film formed of the copolymer; and a medical device provided with the coating film.

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A biocompatible material, which has excellent film formation properties and resistance to water dissolution, and is easily applied on various bases as a coating, while having excellent antithrombotic properties, and to provide an antithrombotic coating agent and an antithrombotic coating film produced by using the biocompatible material, and a medical device provided with the antithrombotic coating film. A copolymer, containing at least one repeating unit (A) represented by formula (1) (wherein, n represents an integer of 2 to 10 and R.sup.1 represents a methyl group or an ethyl group), and at least one repeating unit (B) represented by formula (2) (wherein R.sup.2 represents an aliphatic hydrocarbon group); an antithrombotic coating agent containing the copolymer and an organic solvent; an antithrombotic coating film formed of the copolymer; and a medical device provided with the coating film.

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The invention relates to fine and uniform copolymer powders of partial mixed metal salts of lower alkyl vinyl ether-maleic acid copolymers having a defined particle size distribution. In particular; it relates to powders that are suitably used in the areas of oral care and pharmaceuticals and to methods for preparing the powders. Provided is a composition of powders of partial mixed metal salts of lower alkyl vinyl ether-maleic acid copolymers having: (i) a Dv50 of less than or equal to 25 microns; a Dv90 of less than or equal to 50 microns; and (ii) a particle uniformity reflected by a Dv90/Dv10 ratio of less than or equal to 10.

The invention relates to fine and uniform copolymer powders of partial mixed metal salts of lower alkyl vinyl ether-maleic acid copolymers having a defined particle size distribution. In particular; it relates to powders that are suitably used in the areas of oral care and pharmaceuticals and to methods for preparing the powders. Provided is a composition of powders of partial mixed metal salts of lower alkyl vinyl ether-maleic acid copolymers having: (i) a Dv50 of less than or equal to 25 microns; a Dv90 of less than or equal to 50 microns; and (ii) a particle uniformity reflected by a Dv90/Dv10 ratio of less than or equal to 10.

To provide a curable composition capable of obtaining a cured product excellent in outer appearance and abrasion resistance; a cured product excellent in outer appearance and abrasion resistance; a prepreg capable of obtaining a fiber-reinforced molded product excellent in outer appearance and abrasion resistance; and a fiber-reinforced molded product excellent in outer appearance and abrasion resistance. The curable composition comprises a thermosetting resin, a fluororesin powder and a curing agent, wherein the fluororesin powder is made of a resin material containing a melt-moldable fluororesin having a melting point of from 100 to 325? C. and having functional groups of at least one type selected from the group consisting of carbonyl group-containing groups, hydroxy groups, epoxy groups and isocyanate groups, and in 100 mass % of the total of the thermosetting resin and the fluororesin powder, the proportion of the thermosetting resin is from 70.0 to 99.9 mass % and the proportion of the fluororesin powder is from 0.1 to 30 mass %.

To provide a curable composition capable of obtaining a cured product excellent in outer appearance and abrasion resistance; a cured product excellent in outer appearance and abrasion resistance; a prepreg capable of obtaining a fiber-reinforced molded product excellent in outer appearance and abrasion resistance; and a fiber-reinforced molded product excellent in outer appearance and abrasion resistance. The curable composition comprises a thermosetting resin, a fluororesin powder and a curing agent, wherein the fluororesin powder is made of a resin material containing a melt-moldable fluororesin having a melting point of from 100 to 325? C. and having functional groups of at least one type selected from the group consisting of carbonyl group-containing groups, hydroxy groups, epoxy groups and isocyanate groups, and in 100 mass % of the total of the thermosetting resin and the fluororesin powder, the proportion of the thermosetting resin is from 70.0 to 99.9 mass % and the proportion of the fluororesin powder is from 0.1 to 30 mass %.

A medical elongated body including a tubular main body and a hub connected to the tubular main body. The medical elongated body includes a strain relief supported by a distal portion of the hub. The strain relief surrounds a predetermined range of the proximal portion of the tubular main body. The medical elongated body includes a hydrophilic lubricating coating layer and a temperature responsive lubricating coating layer on the outer surface of the tubular main body, the temperature responsive lubricating coating layer being proximal to the hydrophilic lubricating coating layer. The hydrophilic lubricating coating layer exhibits lubricating characteristics when wet. The temperature responsive lubricating coating layer exhibits hydrophilic characteristics and lubricating characteristics at a temperature lower than a critical temperature when wet and exhibits hydrophobic characteristics and non-lubricating characteristics at a temperature equal to or higher than the critical temperature when wet.