The present invention discloses a composition that may be extruded and/or injection moulded, comprising a chemically modified softwood lignin and a polyester selected from PBS (PolyButylene Succinate), PBAT (PolyButylene Adipate Terephthalate) and PCL (PolyCaproLactone) or mixtures thereof. The chemically modified softwood lignin constitutes 10 to 25 weight-% of the total weight of the composition.

The present invention discloses a composition that may be extruded and/or injection moulded, comprising a chemically modified softwood lignin and a polyester selected from PBS (PolyButylene Succinate), PBAT (PolyButylene Adipate Terephthalate) and PCL (PolyCaproLactone) or mixtures thereof. The chemically modified softwood lignin constitutes 10 to 25 weight-% of the total weight of the composition.

A biodegradable aqueous mixture for coating substrates is disclosed, which includes from about 35 to about 75 weight percent water and from about 25 to about 65 weight percent solids. The solids in turn are made up of from about 40 to about 99 weight percent polyhydroxyalkanoates based on the total dry weight of the solids. Moreover, the polyhydroxyalkanoates are in the form of polyhydroxyalkanoate particles having a moisture content of no less than about 1% by weight prior to mixing with the water and a Dv (90) particle size of no more than about 10 microns, as determined using ISO 8130-13:2019.

A biodegradable aqueous mixture for coating substrates is disclosed, which includes from about 35 to about 75 weight percent water and from about 25 to about 65 weight percent solids. The solids in turn are made up of from about 40 to about 99 weight percent polyhydroxyalkanoates based on the total dry weight of the solids. Moreover, the polyhydroxyalkanoates are in the form of polyhydroxyalkanoate particles having a moisture content of no less than about 1% by weight prior to mixing with the water and a Dv (90) particle size of no more than about 10 microns, as determined using ISO 8130-13:2019.

A functionally gradient material for guided periodontal hard and soft tissue regeneration includes a 3D printed scaffold layer and an electrospun fibrous membrane layer. The content of hydroxyapatite in the 3D printed scaffold layer is higher than the content of hydroxyapatite in the electrospun fibrous membrane layer. The pore size of the 3D printed scaffold layer is larger than the pore size of the electrospun fibrous membrane layer. The pore size of the 3D printed scaffold layer is 100-1000 μm, and the fiber diameter of the electrospun fibrous membrane layer is 300-5000 nm. The electrospun fibrous membrane layer is in a random distribution or an oriented arrangement or has a mesh structure. The thickness of the electrospun fibrous membrane layer is 0.08-1 mm.

A functionally gradient material for guided periodontal hard and soft tissue regeneration includes a 3D printed scaffold layer and an electrospun fibrous membrane layer. The content of hydroxyapatite in the 3D printed scaffold layer is higher than the content of hydroxyapatite in the electrospun fibrous membrane layer. The pore size of the 3D printed scaffold layer is larger than the pore size of the electrospun fibrous membrane layer. The pore size of the 3D printed scaffold layer is 100-1000 μm, and the fiber diameter of the electrospun fibrous membrane layer is 300-5000 nm. The electrospun fibrous membrane layer is in a random distribution or an oriented arrangement or has a mesh structure. The thickness of the electrospun fibrous membrane layer is 0.08-1 mm.

An implantable, autonomously growing medical device is disclosed. The device may have an outer, braided outer element that holds an inner core. Degradation and/or softening of the inner core permits the outer element to elongate, allowing the device to grow with surrounding tissue. The growth profile of the medical device can be controlled by altering the shape/material/cure conditions of the inner core, as well as the geometry of the out element.

An implantable, autonomously growing medical device is disclosed. The device may have an outer, braided outer element that holds an inner core. Degradation and/or softening of the inner core permits the outer element to elongate, allowing the device to grow with surrounding tissue. The growth profile of the medical device can be controlled by altering the shape/material/cure conditions of the inner core, as well as the geometry of the out element.

Described herein is a method of coating a prosthetic device, such as an ocular prosthetic device, the method comprising nanoelectrospraying droplets comprising an active ingredient and/or a carrier species onto a surface of the prosthetic device in a predetermined pattern, the nanoelectrospraying involving controlling the flow rate of the droplets from a nozzle of the nanoelectrospraying equipment by controlling the voltage between the nozzle and the ocular prosthetic device. Also described herein are ocular prosthetic device formable according to the method.

Described herein is a method of coating a prosthetic device, such as an ocular prosthetic device, the method comprising nanoelectrospraying droplets comprising an active ingredient and/or a carrier species onto a surface of the prosthetic device in a predetermined pattern, the nanoelectrospraying involving controlling the flow rate of the droplets from a nozzle of the nanoelectrospraying equipment by controlling the voltage between the nozzle and the ocular prosthetic device. Also described herein are ocular prosthetic device formable according to the method.