This invention relates to the design and function of a compressible valve replacement prosthesis, collared or uncollared, which can be deployed into a beating heart without extracorporeal circulation using a transcatheter delivery system. The design as discussed focuses on the deployment of a device via a minimally invasive fashion and by way of example considers a minimally invasive surgical procedure preferably utilizing the intercostal or subxyphoid space for valve introduction. In order to accomplish this, the valve is formed in such a manner that it can be compressed to fit within a delivery system and secondarily ejected from the delivery system into the annulus of a target valve such as a mitral valve or tricuspid valve.

The invention concerns a polymer composite comprising: a. polymer in an amount of 1-99% by weight of the overall weight; b. biscuit cereal meal in an amount of at least 1% by weight of the overall weight; c. optional plasticizer in an amount from 0-50% w/w of component b); d. optional filler, and e. optional additive.

The invention also concerns a process for its preparation, an intermediate, and a solid article comprising the polymer composite.

The invention concerns a polymer composite comprising: a. polymer in an amount of 1-99% by weight of the overall weight; b. biscuit cereal meal in an amount of at least 1% by weight of the overall weight; c. optional plasticizer in an amount from 0-50% w/w of component b); d. optional filler, and e. optional additive.

The invention also concerns a process for its preparation, an intermediate, and a solid article comprising the polymer composite.

The invention concerns a polymer composite comprising: a. polymer in an amount of 1-99% by weight of the overall weight; b. biscuit cereal meal in an amount of at least 1% by weight of the overall weight; c. optional plasticizer in an amount from 0-50% w/w of component b); d. optional filler, and e. optional additive.

The invention also concerns a process for its preparation, an intermediate, and a solid article comprising the polymer composite.

The present specification provides a polymer resin compound, a method for preparing the same, a photosensitive resin composition including the polymer resin compound, and a photosensitive material formed using the photosensitive resin composition.

The present specification provides a polymer resin compound, a method for preparing the same, a photosensitive resin composition including the polymer resin compound, and a photosensitive material formed using the photosensitive resin composition.

A method of producing an osteoinductive bone graft formed of a plurality of electrospun biodegradable fibers is disclosed. The method includes preparing a fibrous scaffold material formed of the plurality of electrospun biodegradable fibers, wherein the plurality of electrospun biodegradable fibers are entangled with each other to form a cotton-wool like structure having inter-fiber spaces forming a microenvironment for cell growth therein, and immersing the fibrous scaffold in a solution containing BMP-2 so that the BMP-2 is bound to the calcium particles exposed on the surface of the fibers. Area of binding site for BMP-2 on calcium particles exposed on a surface of the electrospun biodegradable fibers is adjusted by an amount of the calcium particles contained in the electrospun biodegradable fibers.

A method of producing an osteoinductive bone graft formed of a plurality of electrospun biodegradable fibers is disclosed. The method includes preparing a fibrous scaffold material formed of the plurality of electrospun biodegradable fibers, wherein the plurality of electrospun biodegradable fibers are entangled with each other to form a cotton-wool like structure having inter-fiber spaces forming a microenvironment for cell growth therein, and immersing the fibrous scaffold in a solution containing BMP-2 so that the BMP-2 is bound to the calcium particles exposed on the surface of the fibers. Area of binding site for BMP-2 on calcium particles exposed on a surface of the electrospun biodegradable fibers is adjusted by an amount of the calcium particles contained in the electrospun biodegradable fibers.

A demineralized bone matrix (DBM) scaffold product comprising a plurality of elongate demineralised bone fibres mechanically interconnected with one another in a regular and repeating pattern.

A demineralized bone matrix (DBM) scaffold product comprising a plurality of elongate demineralised bone fibres mechanically interconnected with one another in a regular and repeating pattern.