Embodiments of the present application relate to patterned polymer sheets and processes to prepare the same for sequencing applications. In particular, flexible micro- and nano-patterned polymer sheets are prepared and used as a template surface in sequencing reaction and new polish-free methods of forming isolated hydrogel plugs in nanowells are described.

Herein is disclosed an emulsion comprising a silicone pre-elastomer, glycerol, a cyclodextrin, and a metal catalyst suitable for use in the polymerization of the silicone pre-elastomer, a silicone elastomer formed from the emulsion and dermal patches for release of octenidine formed from the silicone elastomer. Further there is dis-closed methods of forming the emulsion, the silicone elastomer and the dermal patch.

A natural composition for 3D printing comprising alginate from brown seaweed and cellulose nanofibers, wherein the cellulose nanofibers originate from cellulose from the same brown seaweed sample(s) as the alginate.

Described herein are devices for applying an alternating electric field to a living subject or an in vitro medium at a frequency between 100 kHz and 500 kHz. Also described herein are methods of using the described devices for applying an AC electric field to a target region comprising rapidly dividing cells, e.g., cells associated with a variety of disorders or conditions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.

A novel multi-arm polyethylene glycol (PEG) (I) and preparation method thereof. Active derivatives (II) based on the multi-arm PEG. Gels formed of the active derivatives. Drug conjugates formed of the active derivatives and drug molecules and uses thereof in medical preparation. The multi-arm PEG is formed by polymerizing ethylene oxide with pentaerythritol oligomers as initiator, wherein PEG is the same or different and is a —(CH2CH2O)m-, the average value of m is an integer of 3-1000, l is an integer more than or equal to 2. An 8-arm PEG is preferred, wherein l is equal to 3. The active derivatives (II) comprise link groups X attached to PEG and active end groups F attached to X.

The present invention is directed to a polymer composition (C) comprising a first propylene homopolymer (H-PP), at least one hydrocarbon oil, at least one nucleating agent and at least one antioxidant, a moulded article formed from said polymer composition, a process for gamma-ray sterilization of said moulded article and uses of hydrocarbon oil in said polymer composition for improving resistance to gamma-ray radiation and reducing discoloration after gamma-ray sterilization in said polymer composition.

The present disclosure relates to a medical silicon rubber having high mechanical property and a preparation method thereof. The medical silicon rubber comprises the following raw materials in parts by weight: 50˜90 parts of silicon rubber, 10˜50 parts of polyurethane, 10˜50 parts of fillers, 2˜6 parts of hydrogen-containing silicon oil and 2˜5 parts of a vulcanizing agent. The preparation method comprises: evenly mixing a part of fillers with silicon rubber in an internal mixer for later use, and evenly mixing the other part of fillers with polyurethane in the internal mixer; and mixing the mixed polyurethane on an open type rubber refining machine, then successively adding hydrogen-containing silicon oil, the evenly mixed silicon rubber and the vulcanizing agent into the open type rubber refining machine many times by small portions, and finally vulcanizing the mixed rubber on a plate rubber vulcanizing machine for 5˜15 min at 150˜190° C.

Disclosed are methods, compositions, reagents, systems, and kits to prepare and utilize poly (β-amino ester) (PBAE) polymers, which are synthesized via Michael addition reactions of diacrylates and amines disclosed herein. Various embodiments utilize lactones and lactone derivatives to generate the diacrylate compounds. The PBAE polymers are shown to be effective biodegradable carriers for the delivery of an agent such as an organic molecule, inorganic molecule, nucleic acid, protein, peptide, polynucleotide, targeting agent, an isotopically labeled chemical compound, vaccine, or an immunological agent.

A method for synthesising polymers through devulcanisation from waste containing elastomers, the method including: —a) contacting the waste containing elastomers with a solvent in the presence of a devulcanisation agent, b) heating the mixture produced in step a), at a temperature of between 20° C. and 250° C. for a period of between 15 minutes and 24 hours in the presence of a devulcanisation agent, the concentration of devulcanisation agent, and the ratio between the concentration of devulcanisation agent, expressed as parts per hundred of elastomer (phr) and a volume of solvent, expressed in ml, is: greater than 0.3 phr/ml of solvent or less than 0.2 phr/ml of solvent when the method is carried out in air, greater than 0.06 phr/ml of solvent when the method is carried out in an inert atmosphere.

Embodiments herein relate to compositions of and methods for live viruses. In certain embodiments, a live, attenuated virus composition includes, but is not limited to, one or more live, attenuated viruses and compositions to reduce inactivation and/or degradation of the live, attenuated virus. In other embodiments, the live, attenuated virus composition may be a vaccine composition. In yet other compositions, a live, attenuated virus composition may include at least one carbohydrate, at least one protein and at least one high molecular weight surfactants for reducing inactivation and/or degradation of the live, attenuated virus.