Provided are a near-infrared absorbing composition including a near-infrared absorbing pigment having an oxocarbon skeleton, a coloring agent derivative, a resin, and a solvent, in which the coloring agent derivative is a compound having a cation and an anion in a molecule, and the near-infrared absorbing composition contains 0.5 to 25 parts by mass of the coloring agent derivative with respect to 100 parts by mass of the near-infrared absorbing pigment; a method for producing a dispersion liquid; a film; an optical filter; a method for forming a pattern; a laminate; a solid-state imaging element; an image display device; and an infrared sensor.

The present disclosure provides SWIR-active small molecule polymethine dyes with improved properties for use in optical imaging, photothermal therapy, photodynamic therapy, and SWIR-promoted drug delivery.

There are provided a wavelength selective absorption filter including a resin, and four types of dyes A to D each having a main absorption wavelength range in different specific wavelength regions, in which an absorbance Ab (λ) of the wavelength selective absorption filter at a wavelength λ nm satisfies specific Relational Expressions (I) to (VI), and an organic electroluminescent display device.

Disclosed herein are compounds or salts and/or solvates of formula I, II and III, where the compounds or salts and/or solvates have the following structures: (X).sub.a—Y—(Z).sub.b I; II; or X′—Y′ III; where X, Y, Z, Y′, a, b, R.sub.4, R.sub.6 and R.sub.7 are as defined herein.

##STR00001##

Neurokinin-1 (NK-1) receptor-binding agent delivery conjugates, compositions comprising NK-1 receptor-binding agent delivery conjugates, and methods for making and administering NK-1 receptor-binding agent delivery conjugates are provided. A conjugate may include an NK-1 receptor-binding moiety, a tinker group containing at least one linker selected from the group of a releasable linker and a spacer linker, and an active agent linked to the linker group. The active agent may be selected from the group of fluorophore-containing compounds, radionuclide-containing compounds, and therapeutic agents for treatment of tumor cells characterized by over-expression of the NK-1 receptor.

Neurokinin-1 (NK-1) receptor-binding agent delivery conjugates, compositions comprising NK-1 receptor-binding agent delivery conjugates, and methods for making and administering NK-1 receptor-binding agent delivery conjugates are provided. A conjugate may include an NK-1 receptor-binding moiety, a linker group containing at least one linker selected from the group of a releasable linker and a spacer linker, and an active agent linked to the linker group. The active agent may be selected from the group of fluorophore-containing compounds, radionuclide-containing compounds, and therapeutic agents for treatment of tumor cells characterized by over-expression of the NK-1 receptor.

Hydrogels that degrade under appropriate conditions of pH and temperature by virtue of crosslinking compounds that cleave through an elimination reaction are described. The hydrogels may be used for delivery of various agents, such as pharmaceuticals.

The instant invention provides near-infrared fluorescent biological contrast agents and methods of using them.

Near-infrared activatable fluorescent small molecules for the photodynamic treatment of cancer are provided. Methods of treatment include contacting a plurality of cells of the cancer with a near-infrared activatable fluorescent small molecule and directing a near-IR light to the molecule for an amount of time sufficient to induce release of the active platinum species and a reactive oxygen species.

A luminescent solar concentrator (LSC) device is provided. The LSC device has an active layer including a modified luminophore having a polymethine component including a plurality of methine groups (═CH—).sub.n, where n is an odd integer greater than 1. A hydrogen atom (H) of one of the plurality of methine groups is replaced by one of -AR.sub.1R.sub.2 or -DR.sub.3, where A is selected from nitrogen (N), phosphorus (P), arsenic (As) and antimony (Sb) and D is selected from oxygen (O), sulfur (S), selenium (Se), and tellurium (Te), R.sub.1 and R.sub.2 are independently selected from H, aliphatic groups, and aromatic groups bound to A through a carbon atom, or R.sub.1 and R.sub.2 together form an alicyclic ring containing A, and R.sub.3 is selected from H, aliphatic groups, aromatic groups, and alicyclic groups bound to D through a carbon atom.