Provided are dyes and compositions which are useful in a number of applications, such as the detection and monitoring protein aggregation, kinetic studies of protein aggregation, neurofibrillary plaques analysis, evaluation of protein formulation stability, and analysis of molecular chaperone activity.

According to the present teachings, compositions, kits, and methods for protein melt analysis are provided that utilizing one or more fluorophore dyes. In some embodiments, a method comprises preparing a sample by mixing at least one protein with two or more dyes, and applying a controlled heating, while recording the fluorescence emission of the sample. The methods can be used, for example, for screening conditions for optimized protein stability, screening for ligands that bind and enhance protein stability (e.g., protein-protein interactions), screening for mutations for enhanced stability, screening crystallization conditions for protein stability, screening storage conditions for protein stability, and screening conditions in which a protein will be used (e.g., production conditions, treatment conditions, etc.) for protein stability.

A dye composition dissolvable within a liquid crystal host device (including: polymer dispersed liquid crystal, polymer network liquid crystal, polymer stabilized liquid crystal, liquid crystal displays and similar devices), comprising eutectic mixtures of dichroic metallomesogen molecules. The aforesaid metallomesogen molecules comprise chromophore groups synthesized by physical and chemical mixing methods.

A yellow toner which provides, even in small amounts, a sharper color and brighter gloss, and higher reflection density than ever before, and which has excellent light resistance. The yellow toner contains a binder resin and a yellow colorant, wherein, as the yellow colorant, at least one of the compound A represented by the following general formula (1) and the compound B represented by the following general formula (2), and the compound C represented by the following formula (3) are contained:

##STR00001##

Provided are a protective sheet and a spectacle lens including at least one dye selected from the group consisting of a dye represented by Formula (1) and a dye represented by Formula (2), and application thereof. In Formula (1), R.sup.71 to R.sup.74 each independently represent a hydrogen atom, an alkyl group, an alkoxy group, or the like. In Formula (2), R.sup.21 represents an alkyl group, an aryl group, a heterocyclic group, or the like, R.sup.22 represents a hydrogen atom, a halogen atom, an alkyl group, or the like, and at least one of R.sup.21 or R.sup.22 is an alkyl group having 4 or more carbon atoms. n represents 0 or 1, and m represents an integer of 1 to 5. ##STR00001##

The present invention discloses a adhesive sheet effectively blocking light in the ultraviolet light region without deteriorating the transmittance with respect to the visible light region and the adhesiveness and a adhesive composition including binder resin and light absorption dye dispersed in the binder resin, and it is possible to effectively block light under the 410 nm wavelength region and to be applied to a various kinds of display devices.

[This] charge transport material which comprises a compound expressed by the following formula has a high efficiency and drive durability after high-temperature storage and resists the occurrence of dark spots (X.sup.101 represents a sulfur atom or an oxygen atom; R.sup.101 and R.sup.102 represent each independently an alkyl group, an aryl group, a heteroaryl group, a fluorine atom, or a silyl group, and may further be substituted with these groups; n101 represents an integer from 0 to 11; n102 represents an integer from 0 to 7; a plurality of R.sup.101 and R.sup.102 [groups] may be the same or different; and L.sup.101 represents a single bond or a divalent linking group; however, one of R.sup.101, L.sup.101, and R.sup.102 includes a fluorine atom, a fluoroalkyl group, a cycloalkyl group, a cycloalkylene group, a silyl group, an alkylsilyl group, an arylsilyl group, or a silicon atom linking group.) ##STR00001##

Novel fluorescent whitening agents, compositions or mixtures thereof with known fluorescent whitening agents, their preparation, and their use. The novel fluorescent whitening agents (FWAs) contain three structural subunits derived from 4,4-diamino-2,2-stilbenedisulfonic acid. The novel compounds and their mixtures with known FWAs show very good effectiveness as fluorescent whitening agents for cellulosic materials, in particular for paper.

Fluorescence quenching nitrodiarylethene analogs are useful in oligonucleotide conjugates and probes. These analogs, whose absorption spectra are substantially blue-shifted relatively to emission spectra of common fluorophores (such as fluorescein), do not need to rely on spectral overlap of quencher absorbance and fluorophore's emission for their quenching abilities. The oligonucleotide-quencher conjugates may be used in detection methods for nucleic acid targets.

The present invention discloses the spiropyran compound of formula (I), process for preparation thereof and a composition comprising spiropyran compound of formula (I) on a support, wherein said support selected from polymers such as Poly (ethylene oxide), Polydimethylsiloxane (PDMS), Ethylene propylene diene monomer (EPDM).