An organic light-emitting device including a first electrode; a second electrode; an organic layer between the first electrode and the second electrode and including an emission layer; and an electron transport region between the second electrode and the emission layer, the electron transport region including a charge control layer, wherein the charge control layer includes a first compound represented by Formula 1 and a second compound represented by Formula 2: ##STR00001##

The post-translational modification (PTM) and signaling molecule poly(ADP-ribose) (PAR) has an impact on diverse biological processes. PTM is regulated by a series of ADP-ribosyl glycohydrolases (PARG enzymes) that cleave polymers and/or liberate monomers from their protein targets. Disclosed herein is a substrate for monitoring PARG activity, TFMU-ADPr, which directly reports on total PAR hydrolase activity via release of a fluorophore; this substrate has excellent reactivity, generality, stability, and usability. A second substrate, TFMU-IDPr, selectively reports on PARG activity only from the enzyme ARH3. Use of these probes in whole-cell lysate experiments has revealed a mechanism by which ARH3 is inhibited by cholera toxin. TFMU-ADPr and TFMU-IDPr are versatile tools for assessing small-molecule inhibitors in vitro and probing the regulation of ADP-ribosyl catabolic enzymes.

The invention relates to novel luminescent compositions of matter containing a fluorophore, synthetic methods for making the compositions, macromolecular conjugates of the compositions, and the use of the compositions in various methods of detection. The invention also provides kits containing the compositions and their conjugates for use in the methods of detection.

The present application relates to substituted coumarin derivatives and their uses as fluorescent labels. These compounds may be used as fluorescent labels for nucleotides in nucleic acid sequencing applications.

The present application relates to substituted coumarin derivatives and their uses as fluorescent labels. These compounds may be used as fluorescent labels for nucleotides in nucleic acid sequencing applications.

Mass spectrometry (MS) active, fluorescent rapid tagging reagent is provided having three substituent groups: (a) a tertiary amino group or other MS active atom; (b) a highly fluorescent moiety; and (c) a reactive group that can react with an amine. The reactive group provides rapid tagging of desired bio-molecules. The fluorescent moiety provides the fluorescent signal. The tertiary amino group provides the MS signal.

The present invention concerns an organic dye comprising a photochromic entity, a segment -eD representing an electron donor segment and a segment -L-A with -L- representing a covalent bond or a spacer segment and particularly a pi-conjugated spacer segment, and -A representing an electron attractor segment able to form a covalent bond with a semi-conductor. The present invention concerns the use thereof as photosensitizer in a photovoltaic device and said photovoltaic device.

The present invention describes novel 7-alkylamino-3-(thienyl) coumarin fluorescent dyes of formula (I)

##STR00001##

These dyes are water soluble, can be excited by the 405 nm excitation source and exhibit a large Stokes shift (≧80 nm). Furthermore, the dyes possess a reactive group for the labeling of biomolecules or other analytes.

The present invention describes novel 7-alkylamino-3-(thienyl) coumarin fluorescent dyes of formula (I)

##STR00001##

These dyes are water soluble, can be excited by the 405 nm excitation source and exhibit a large Stokes shift (≧80 nm). Furthermore, the dyes possess a reactive group for the labeling of biomolecules or other analytes.

The present application relates to new coumarin compounds and their uses as fluorescent labels. The compounds may be used as fluorescent labels for nucleotides in nucleic acid sequencing applications.