C12M1/22

Stacked Recirculating Bioreactor

The instant disclosure provides a system comprising a plurality of stacked bioreactors, wherein the system is configured to provide a substantially equal flow rate of fluid and pressure drop through each of the plurality of bioreactors. In some embodiments, the flow of the fluid through each of the plurality of bioreactors is configured to generate physiological shear rates to induce a biological source material in the bioreactors to produce target biological products.

Device for in vitro culture of embryos and fabrication method thereof

A device for in vitro culture of embryos includes: an array having at least one well formed therein; and a bottom surface formed in the well and made of polydimethylsiloxane (PDMS). The use of the culture vessel having the well bottom surface made of PDMS has the effect of further increasing the blastocyst formation rate of embryos compared to the use of conventional arrays made of plastic.

Sample processing method and sample culturing method
11124820 · 2021-09-21 · ·

Provided is a sample processing method that liquefies a medium solution by making a liquid that liquefies the medium solution act on a sample formed by gelating or solidifying the medium solution that is supported by a substrate while an observation subject is included therein, while maintaining a state in which the medium solution is supported by the substrate while the observation subject is included therein.

POLYLACTIDE CELL CULTURE CONTAINERS AND USE IN CELL CULTURE WITHOUT SURFACE MODIFICATION
20210171891 · 2021-06-10 ·

2D and 3D cell culture containers formed from blends of poly-L-lactide and poly-D-lactide provide growth surfaces for adherent cells and do not require surface treatment or coating to support mammalian cell growth. The cell culture containers are transparent, heat tolerant, and are environmentally degradable and suitable for composting in landfills.

Device and Method for Automatic Processing of Culture Plates for Microbiological Samples
20210115386 · 2021-04-22 · ·

An automatic processing device of culture plates (2) for microbiological samples, wherein the processing device (1) includes a support frame (3); a slide (4) provided with a seating (5) configured for removably housing a culture plate (2) and movably mounted on the support frame (3) so as to be selectively displaceable between a first loading position, a plurality of image-acquiring positions, and a first unloading; a camera (6) of a linear type, provided with an optic (7) of a telecentric type and a trilinear sensor, and arranged according to a vertical axis (8) such as to acquire, at an image-acquiring zone, a multiplicity of linear images of corresponding linear portions of an upper surface of the culture plate (2), during the displacing of the slide (4); a first lighting device (11) orientated such as to illuminate the linear portions of an upper surface of the culture plate (2); an advancing device (14) of the slide (4) configured such as to enable obtaining a constant and substantially vibration-free advancing speed of the slide (4) in the image-acquiring zone; and an electronic control device (9) of a functioning of the camera (6), of the lighting device and of the advancing device (14).

MICROPLATES FOR MAGNETIC 3D CULTURE
20210163881 · 2021-06-03 ·

Devices for magnetic 3d culture are described including magnetic lids/bases for single Petri plates and adjustable height cap for same. Similar devices for multi-magnet culture plates wherein multiwell plates have all adjacent magnets orientated in the opposite polarity, and methods of making same.

System for analyzing and sorting of petri dishes

A system for analyzing and sorting of petri dishes comprising an analysis tool, a control unit, a first elevator movable along a first elevator axis, a conveyor with a conveyor plane, and at least one carrier built to carry the petri dishes along a carrier axis. The analysis tool is built to assign information to the petri dish, and in case of a first information assigned to the petri dish the control unit is built to move the first elevator into a carrier position, wherein, as soon as the first elevator reaches the carrier position, the control unit is built to move a substantially flat first plate along the first elevator axis from a first neutral position located in the conveyor plane into a first transfer position.

Prepared plated media product
11028354 · 2021-06-08 · ·

The present invention relates to systems and methods involving interconnected plate components, including bases, lids and covers, interconnected in a manner such that a continuous strip of each component is prepared. The continuous strips may be stored as rollstock in a reel style. The physical properties of each continuous strip allow the base, lid and/or cover to include means for positive control. In one embodiment, the continuous strip of bases is advanced and processed through an automated system with positive control, and remains in the form of a continuous strip until agar in the bases is cured, at which time the bases are singulated. When a lid is applied to a base using methods described herein, an airtight seal is formed improving the quality of culture media used in testing.

PORTABLE INCUBATION DEVICE
20210147785 · 2021-05-20 ·

The invention relates to portable incubation device comprising a device housing (14) accommodating an incubation chamber housing (3) defining an incubation chamber (9) with an opening (4) together with a feed system (1) and a temperature control system of the heating module (2), characterised in that in the incubation chamber (9) there is at least one heating system (6) comprising at least one heating module (7), preferably two, wherein on the heating system (6) there is a supported a frame (10) supporting a culturing dish (11), and wherein the temperature control system of the heating module (2) provides continuous real time regulation of the desired incubation temperature in the incubation chamber (9).

Culture device for lactic acid bacteria

The present disclosure provides a culture device for enumerating colonies of microorganisms. The device can comprise a base, a coversheet, and a nonporous spacer member disposed therebetween. The spacer member comprises an aperture that defines a growth compartment. Disposed in the growth compartment are a cold water-soluble gelling agent, a dry oxygen-scavenging reagent, a dry buffer system, and an effective amount of a dry carbon dioxide-generating reagent. The buffer system is selected such that, when the growth compartment is hydrated with a predetermined volume of deionized water, an aqueous mixture with a pH less than or equal to 6.35 is formed.