A photobioreactor for cultivating photoautotrophs that comprises a first hatcher for containing the photoautotrophs and a first feed medium; a second hatcher for holding the photoautotrophs and a second feed medium; and a pump connected to the first hatcher, the second hatcher or both the first hatcher and the second hatcher for moving the photoautotrophs between the first hatcher and the second hatcher or vice versa.

Scalable biomaterial-based bioreactors are described. In one embodiment, the bioreactor may comprise perforated plates stacked such that the assembled bioreactor has the necessary manifolds and chambers to transport gas and liquids to a biomaterial contained within the bioreactor, and to remove the reaction products. In another embodiment, single use bioreactors are described. Methods of operating the bioreactors are also described.

The invention relates to a novel plasma induced mutation breeding device which comprises: a sample treatment system including a sterile working compartment free of bioactive contaminant; a plasma generator; a radio frequency (RF) power module connected with the plasma generator; a cooling system for cooling the plasma generator; a detection system including a gas flow controller for controlling the gas flow which generates the plasma jet and a temperature sensor for detecting the temperature of the jet emitted by the plasma generator; and a control system with an operation panel and a controller for controlling the operation of the mutation breeding device, wherein the controller is connected with the RF power module, gas flow controller, temperature sensor, cooling system as well as the operation panel, respectively, and said plasma generator stably emits the plasma jet at 37±3° C. during the biological sample processing.

A cell culture vessel including an accommodating part which is an inner space accommodating a cell culture support therein, a fixing member configured to fix the cell culture support to a lower surface of the accommodating part, wherein the fixing member includes a first adhesive layer attached to the lower surface of the accommodating part, a second adhesive layer attached to a lower surface of the cell culture support, and a support film interposed between the first adhesive layer and the second adhesive layer and configured to perform a support function, and an adhesive force between the second adhesive layer and the cell culture support is higher than an adhesive force between the first adhesive layer and the lower surface of the accommodating part.

A mixing device for an application in a container including a rotatable shaft; a drive device through which the rotatable shaft is drivable; and at least one mixing element arranged at the shaft, wherein the mixing element is rotatable together with the shaft, wherein the shaft includes a support device connected with the shaft, wherein the support device is arranged in an end portion of the shaft that is oriented away from the drive device, wherein the shaft is rotatable about its longitudinal axis relative to the support device, wherein the mixing device is supportable through the support device in a receiving device connected with the container, wherein the support device is moveable by a straight bearing or a rolling element bearing along a guide device into the receiving device, wherein the straight bearing includes at least one sliding surface that is moveable on a corresponding sliding surface.

A cell culture device includes a main body and a plug element. The main body includes a slot, an open groove and a fluid chamber. The open groove is connected with one side of the slot. The fluid chamber is disposed inside the main body and connected with another side of the slot. The plug element includes a first cell culture chamber and a first porous membrane. The first porous membrane is disposed at one side of the first cell culture chamber. The plug element is detachably plugged into the slot. When the plug element is plugged into the slot, the first cell culture chamber is communicated with the open groove to form an open space, and the open space and the fluid chamber are separated by the first porous membrane.

The cultivation, by optimized growth and harvesting of algae derived bio-mass may provide useful feedstock for various products and processes. The present invention provides an apparatus that allows for the optimized growth and harvesting of algae within a photo-bioreactor. The photo-bioreactor may include a channel and a propulsion unit for circulating an algae mixture through a channel while exposing the algae mixture to light to support photosynthesis and growth of the algae. A method is also provided for the optimizing the growth and harvesting of algae utilizing a number of different input streams. Further, a system including a programmable control assembly is provided for the growth and harvesting of algae.

A cell culture apparatus including cell culture units U and a measurement part (5). The measurement part (5) is provided with an imaging part (51) and is disposed so as to be capable of moving up and down between a back panel part (21) of a casing (2) and a culture container accommodating shelf (32). When the measurement unit (5) reaches a measurement position of each cell culture unit U which is a measurement subject, the culture container accommodating shelf (32) slides toward the measurement unit (5) so that portions to be measured of culture containers U20, U30 in each cell culture unit U come in an imaging range of the imaging part (51).

A embryo culture dish comprising: a first sidewall; a second sidewall attached to the first sidewall; a third sidewall attached to the second sidewall; a fourth sidewall attached to the third and first sidewalls, the four sidewalls forming an outer perimeter that forms a generally rectangular shape; a dish floor that is generally in communication with the four sidewalls, the dish floor comprising: a top surface that is at a first elevation; at least one rectangular shaped embryo culture well, the at least one rectangular shaped embryo culture well comprising: an outer perimeter that has generally a rectangular shape; a first slanted wall that comprises a first side of the rectangular shaped embryo culture well; a second slanted wall that comprises an opposite side from the first side of the rectangular shaped embryo culture well, the first and second slanted walls extend downward and towards each other until they both intersect with a well floor of the rectangular shaped embryo culture well, the well floor having a well top surface, and where the well top surface is at a second elevation, the second elevation being below the first elevation; at least one shaped well, the shaped well comprising: an outer perimeter that has generally a shape; a shaped well floor, the shaped well floor having a shaped well floor top surface, and where the shaped well floor top surface is at a third elevation, the third elevation being below the first elevation. A method of using a square time-lapse dish, the method comprising: adding a medium to a square time lapse dish; tilting the square time-lapse dish to an angle α; removing excess medium from a large well in the time-lapse dish, with the square time-lapse dish at angle α; and returning the square time-lapse dish to a horizontal orientation.

Microfluidic devices, systems, and methods.